Showing 541 - 560 results of 8,722 for search '"medicinal chemistry"', query time: 0.76s Refine Results
  1. 541
    Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging

    Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging by Zhengxing Zhang, Joseph Lau, Chengcheng Zhang, Nadine Colpo, Alessio Nocentini, Claudiu T. Supuran, François Bénard, Kuo-Shyan Lin

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  2. 542
    Design and synthesis of 4-piperazinyl quinoline derived urea/thioureas for anti-breast cancer activity by a hybrid pharmacophore approach

    Design and synthesis of 4-piperazinyl quinoline derived urea/thioureas for anti-breast cancer activity by a hybrid pharmacophore approach by Raja Solomon Viswas, Sheetal Pundir, Hoyun Lee

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  3. 543
    Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer

    Exploration of novel heterofused 1,2,4-triazine derivative in colorectal cancer by Justyna Magdalena Hermanowicz, Anna Szymanowska, Beata Sieklucka, Robert Czarnomysy, Krystyna Pawlak, Anna Bielawska, Krzysztof Bielawski, Joanna Kalafut, Alicja Przybyszewska, Arkadiusz Surazynski, Adolfo Rivero-Muller, Mariusz Mojzych, Dariusz Pawlak

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  4. 544
    Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents

    Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents by Sudong Liang, Yifei Geng, Miao-Miao Niu, Yan Zhang, Weiping He, Jindong Li, Li Yang, Zhen Xu

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  5. 545
    Polymeric microspheres redefining the landscape of colon-targeted delivery: A contemporary update

    Polymeric microspheres redefining the landscape of colon-targeted delivery: A contemporary update by Raosaheb S. Shendge, Tejas S. Zalte, Shubhangi B. Khade

    Published 2024-08-01
    “…European Journal of Medicinal Chemistry Reports…”
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  6. 546
    Discovery of novel anaplastic lymphoma kinase (ALK) and histone deacetylase (HDAC) dual inhibitors exhibiting antiproliferative activity against non-small cell lung cancer

    Discovery of novel anaplastic lymphoma kinase (ALK) and histone deacetylase (HDAC) dual inhibitors exhibiting antiproliferative activity against non-small cell lung cancer by Kang-Li Wang, Tsung-Yu Yeh, Pei-Chen Hsu, Tzu-Hsuan Wong, Jia-Rong Liu, Ji-Wang Chern, Miao-Hsia Lin, Chao-Wu Yu

    Published 2024-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  7. 547
    Diaryl azo derivatives as anti-diabetic and antimicrobial agents: synthesis, in vitro, kinetic and docking studies

    Diaryl azo derivatives as anti-diabetic and antimicrobial agents: synthesis, in vitro, kinetic and docking studies by Tehreem Tahir, Mirza Imran Shahzad, Rukhsana Tabassum, Muhammad Rafiq, Muhammad Ashfaq, Mubashir Hassan, Katarzyna Kotwica-Mojzych, Mariusz Mojzych

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  8. 548
    The effect of Pd(II) and Pt(II) coordination on the affinity of avibactam to OXA-48 β-lactamase

    The effect of Pd(II) and Pt(II) coordination on the affinity of avibactam to OXA-48 β-lactamase by Jakub Brzeski, Paulina Nowicka, Sergey A. Samsonov

    Published 2023-12-01
    “…European Journal of Medicinal Chemistry Reports…”
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  9. 549
    Investigating the effects of a FAAH inhibitor in the laterodorsal tegmental nucleus using a new ex vivo mouse preparation

    Investigating the effects of a FAAH inhibitor in the laterodorsal tegmental nucleus using a new ex vivo mouse preparation by Bala Krishna Prabhala, Jiwan Chettri, Nagalakshmi Irrinki, Abhroop Garg, Rosa Jersie-Christensen, Håvard Jenssen, Biljana Mojsoska, Neeraj Soni, Kristi A. Kohlmeier

    Published 2023-12-01
    “…European Journal of Medicinal Chemistry Reports…”
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  10. 550
    Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae

    Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae by Alessio Nocentini, Chad S. Hewitt, Margaret D. Mastrolorenzo, Daniel P. Flaherty, Claudiu T. Supuran

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  11. 551
    The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10

    The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10 by Jan Moritz Seliger, Livia Misuri, Edmund Maser, Jan Hintzpeter

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  12. 552
    Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cells

    Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cells by Hyeong jae Kim, Jeong Hee Hong

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  13. 553
    Discovery of (phenylureido)piperidinyl benzamides as prospective inhibitors of bacterial autolysin E from Staphylococcus aureus

    Discovery of (phenylureido)piperidinyl benzamides as prospective inhibitors of bacterial autolysin E from Staphylococcus aureus by Jure Borišek, Sara Pintar, Mitja Ogrizek, Simona Golič Grdadolnik, Vesna Hodnik, Dušan Turk, Andrej Perdih, Marjana Novič

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  14. 554
    Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents

    Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells a... by Wagdy M. Eldehna, Hadia Almahli, Ghada H. Al-Ansary, Hazem A. Ghabbour, Mohamed H. Aly, Omnia E. Ismael, Abdullah Al-Dhfyan, Hatem A. Abdel-Aziz

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  15. 555
    Design, synthesis of new 2,4-thiazolidinediones: In-silico, in-vivo anti-diabetic and anti-inflammatory evaluation

    Design, synthesis of new 2,4-thiazolidinediones: In-silico, in-vivo anti-diabetic and anti-inflammatory evaluation by Shankar Gharge, Shankar G. Alegaon, Shriram D. Ranade, N.A. Khatib, Rohini S. Kavalapure, B.R. Prashantha Kumar, Vinod D, Nandkishor B. Bavage

    Published 2024-08-01
    “…European Journal of Medicinal Chemistry Reports…”
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  16. 556
    Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action

    Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action by Srinivas Angapelly, P. V. Sri Ramya, Rohini Sodhi, Andrea Angeli, Krishnan Rangan, Narayana Nagesh, Claudiu T. Supuran, Mohammed Arifuddin

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  17. 557
    Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group

    Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group by Pasquale Linciano, Luca Pinzi, Silvia Belluti, Ugo Chianese, Rosaria Benedetti, Davide Moi, Lucia Altucci, Silvia Franchini, Carol Imbriano, Claudia Sorbi, Giulio Rastelli

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  18. 558
    Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity

    Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity by Marilia Barreca, Virginia Spanò, Maria Valeria Raimondi, Chiara Tarantelli, Filippo Spriano, Francesco Bertoni, Paola Barraja, Alessandra Montalbano

    Published 2021-07-01
    “…European Journal of Medicinal Chemistry Reports…”
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  19. 559
    Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations

    Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations by Alaa Elwan, Helmy Sakr, Abdel-Ghany A. El-Helby, Ahmed El-morsy, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Mohamed El-Sherbiny, Khaled El-Adl

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  20. 560
    Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, in vitro and in silico studies

    Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, in vitro and in silico studies by Dina I. A. Othman, Abdelrahman Hamdi, Samar S. Tawfik, Abdullah A. Elgazar, Amany S. Mostafa

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article

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