Showing 561 - 580 results of 8,722 for search '"medicinal chemistry"', query time: 0.28s Refine Results
  1. 561
    Investigation of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates as carbonic anhydrase inhibitors

    Investigation of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates as carbonic anhydrase inhibitors by Morteza Abdoli, Alessandro Bonardi, Claudiu T. Supuran, Raivis Žalubovskis

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  2. 562
    Multitargeting approaches involving carbonic anhydrase inhibitors: hybrid drugs against a variety of disorders

    Multitargeting approaches involving carbonic anhydrase inhibitors: hybrid drugs against a variety of disorders by Claudiu T. Supuran

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  3. 563
    Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase

    Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase by Bo Ram Kim, Ji-Young Park, Hyung Jae Jeong, Hyung-Jun Kwon, Su-Jin Park, In-Chul Lee, Young Bae Ryu, Woo Song Lee

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  4. 564
    Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study

    Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular... by Salma Fares, Khalid B. Selim, Fatma E. Goda, Magda A. A. El-Sayed, Nawaf A. AlSaif, Mohamed M. Hefnawy, Alaa A.-M. Abdel-Aziz, Adel S. El-Azab

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  5. 565
    Selective inhibition of carbonic anhydrase IX by sulphonylated 1,2,3-triazole incorporated benzenesulphonamides capable of inducing apoptosis

    Selective inhibition of carbonic anhydrase IX by sulphonylated 1,2,3-triazole incorporated benzenesulphonamides capable of inducing apoptosis by Kiran Siwach, Amit Kumar, Harish Panchal, Rajiv Kumar, Jitender Kumar Bhardwaj, Andrea Angeli, Claudiu T. Supuran, Pawan K. Sharma

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  6. 566
    Targeting allosteric sites of human aromatase: a comprehensive in-silico and in-vitro workflow to find potential plant-based anti-breast cancer therapeutics

    Targeting allosteric sites of human aromatase: a comprehensive in-silico and in-vitro workflow to find potential plant-based anti-breast cancer therapeutics by Hani A. Alhadrami, Ahmed M. Sayed, Sami A. Melebari, Asem A. Khogeer, Wesam H. Abdulaal, Mohamed B. Al-Fageeh, Mohammad Algahtani, Mostafa E. Rateb

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  7. 567
    Rapidly screening of α-glucosidase inhibitors from Dioscorea opposita Thunb. peel based on rGO@Fe3O4 nanocomposites microreactor

    Rapidly screening of α-glucosidase inhibitors from Dioscorea opposita Thunb. peel based on rGO@Fe3O4 nanocomposites microreactor by Songsong Zhang, Beibei Qiu, Jinhua Zhu, Weiping Hu, Fanyi Ma, M. Z. H. Khan, Xiuhua Liu

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  8. 568
    Hydroxyl-substituted double Schiff-base condensed 4-piperidone/cyclohexanones as potential anticancer agents with biological evaluation

    Hydroxyl-substituted double Schiff-base condensed 4-piperidone/cyclohexanones as potential anticancer agents with biological evaluation by Lianshuang Zhang, Qin Chen, Guige Hou, Wei Zhao, Yun Hou

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  9. 569
    Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis

    Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis by Ivana Nemčovičová, Katarína Lopušná, Iveta Štibrániová, Fabio Benedetti, Federico Berti, Fulvia Felluga, Sara Drioli, Mattia Vidali, Jaroslav Katrlík, Lucia Pažitná, Alena Holazová, Jana Blahutová, Simona Lenhartová, Monika Sláviková, Boris Klempa, Miroslav Ondrejovič, Daniela Chmelová, Barbora Legerská, Stanislav Miertuš, Mária Klacsová, Daniela Uhríková, Lukáš Kerti, Vladimír Frecer

    Published 2024-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  10. 570
    Discovery of novel ATAD2 bromodomain inhibitors that trigger apoptosis and autophagy in breast cells by structure-based virtual screening

    Discovery of novel ATAD2 bromodomain inhibitors that trigger apoptosis and autophagy in breast cells by structure-based virtual screening by Dahong Yao, Jin Zhang, Jinhui Wang, Dabo Pan, Zhendan He

    Published 2020-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  11. 571
    Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers

    Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers by Chao Wang, Yuelin Li, Zi Liu, Zeyu Wang, Zihan Liu, Shuai Man, Yujing Zhang, Kai Bao, Yingliang Wu, Qi Guan, Daiying Zuo, Weige Zhang

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  12. 572
    Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core

    Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core by Ravi Tripathi, Abiodun Anifowose, Wen Lu, Xiaoxiao Yang, Binghe Wang

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  13. 573
    Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

    Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities by Zofia Chrienova, Eugenie Nepovimova, Rudolf Andrys, Rafael Dolezal, Jana Janockova, Lubica Muckova, Lenka Fabova, Ondrej Soukup, Patrik Oleksak, Martin Valis, Jan Korabecny, José Marco-Contelles, Kamil Kuca

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  14. 574
    Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation

    Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation by Mohamed Hagras, Moshira A. El Deeb, Heba S. A. Elzahabi, Eslam B. Elkaeed, Ahmed B. M. Mehany, Ibrahim H. Eissa

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  15. 575
    Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors

    Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors by Ibrahim M. Salem, Samia M. Mostafa, Ismail Salama, Osama I. El-Sabbagh, Wael A. H. Hegazy, Tarek S. Ibrahim

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  16. 576
    Zinc binding groups for histone deacetylase inhibitors

    Zinc binding groups for histone deacetylase inhibitors by Lei Zhang, Jian Zhang, Qixiao Jiang, Li Zhang, Weiguo Song

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  17. 577
    Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents

    Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents by Chao Wang, Yujing Zhang, Lingyu Shi, Shanbo Yang, Jing Chang, Yingjie Zhong, Qian Li, Dongming Xing

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  18. 578
    Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani

    Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani by Alessio Nocentini, Sameh M. Osman, Igor A. Rodrigues, Veronica S. Cardoso, Fatmah Ali S. Alasmary, Zeid AlOthman, Alane B. Vermelho, Paola Gratteri, Claudiu T. Supuran

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  19. 579
    Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M

    Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M by Moustafa O. Aboelez, Amany Belal, Guangya Xiang, Xiang Ma

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  20. 580
    Correction to: Inhibitors of alanine racemase enzyme: a review

    Correction to: Inhibitors of alanine racemase enzyme: a review

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article

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