Showing 641 - 660 results of 8,722 for search '"medicinal chemistry"', query time: 0.28s Refine Results
  1. 641
    Synthesis and evaluation of hydrogen peroxide sensitive tofacitinib prodrugs

    Synthesis and evaluation of hydrogen peroxide sensitive tofacitinib prodrugs by Viola Previtali, Ulrik Bering Keiding, Asger Hegelund Olsen, Jorge Peiró Cadahía, Anne Skovsbo Clausen, Andreas Kjaer, Thomas Lars Andresen, Anders Elias Hansen, Mads Hartvig Clausen

    Published 2022-04-01
    “…European Journal of Medicinal Chemistry Reports…”
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  2. 642
    Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases

    Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases by Weiwei An, Katrina J. Holly, Alessio Nocentini, Ryan D. Imhoff, Chad. S. Hewitt, Nader S. Abutaleb, Xufeng Cao, Mohamed N. Seleem, Claudiu T. Supuran, Daniel P. Flaherty

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  3. 643
    Coumarins effectively inhibit bacterial α-carbonic anhydrases

    Coumarins effectively inhibit bacterial α-carbonic anhydrases by Simone Giovannuzzi, Chad S. Hewitt, Alessio Nocentini, Clemente Capasso, Daniel P. Flaherty, Claudiu T. Supuran

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  4. 644
    The discovery of a novel series of potential ERRα inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo

    The discovery of a novel series of potential ERRα inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo by Zhipei Gao, Tianxiao Wang, Rui Li, Yongli Du, Han Lv, Liudi Zhang, Haifei Chen, Xiaojin Shi, Qunyi Li, Jingkang Shen

    Published 2022-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  5. 645
    Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition

    Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition by Ester Colarusso, Marianna Potenza, Gianluigi Lauro, Maria Giovanna Chini, Valentina Sepe, Angela Zampella, Katrin Fischer, Robert K. Hofstetter, Oliver Werz, Giuseppe Bifulco

    Published 2022-08-01
    “…European Journal of Medicinal Chemistry Reports…”
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  6. 646
    Cyclic N-locked indolicidin analogues with antimicrobial activity: Effect of ring size and fatty acid acylation

    Cyclic N-locked indolicidin analogues with antimicrobial activity: Effect of ring size and fatty acid acylation by Abdullah Lone, Josefine Eilsø Nielsen, Peter W. Thulstrup, Reidar Lund, Paul Robert Hansen, Håvard Jenssen

    Published 2022-12-01
    “…European Journal of Medicinal Chemistry Reports…”
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  7. 647
    Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase

    Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase by Linda J. Urbanski, Silvia Bua, Andrea Angeli, Marianne Kuuslahti, Vesa. P. Hytönen, Claudiu T. Supuran, Seppo Parkkila

    Published 2020-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  8. 648
    Designing a bis-azide photoaffinity probe in labeling influenza nucleoprotein trimer to give an insight into the binding mode

    Designing a bis-azide photoaffinity probe in labeling influenza nucleoprotein trimer to give an insight into the binding mode by Pin-Hsuan Chiu, Wei Huang, Hua-Ting Hsu, Wen-Feng Huang, Ying-Ta Wu, Ting-Jen Rachel Cheng, Jim-Min Fang

    Published 2022-12-01
    “…European Journal of Medicinal Chemistry Reports…”
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    Article
  9. 649
    Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study

    Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking... by Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Nawaf A. AlSaif, Mohammed M. Alanazi, Manal A. El-Gendy, Ahmad J. Obaidullah, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Ibrahim A. Al-Suwaidan

    Published 2020-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  10. 650
    Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines

    Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines by Filipe N. Franco, Júlia T. Oliveira, Kimberly B. Tecchio, Flaviana A. Santos, Moacyr J.B.M. Rêgo, Francisco J.B. Mendonça-Júnior, Maira G.R. Pitta, Michelly C. Pereira, Rosy I.M.A. Ribeiro, Vanessa J.S.V. Santos, Fabio V. Santos

    Published 2022-04-01
    “…European Journal of Medicinal Chemistry Reports…”
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  11. 651
    Diversely substituted sulfamides for fragment-based drug discovery of carbonic anhydrase inhibitors: synthesis and inhibitory profile

    Diversely substituted sulfamides for fragment-based drug discovery of carbonic anhydrase inhibitors: synthesis and inhibitory profile by Tatiana Sharonova, Petr Zhmurov, Stanislav Kalinin, Alessio Nocentini, Andrea Angeli, Marta Ferraroni, Mikhail Korsakov, Claudiu T. Supuran, Mikhail Krasavin

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  12. 652
    Piperazine tethered heterocyclic hybrids: Synthesis, characterization, and in vitro studies from potent proteinase inhibitors to antiproliferative activity

    Piperazine tethered heterocyclic hybrids: Synthesis, characterization, and in vitro studies from potent proteinase inhibitors to antiproliferative activity by Lairikyengbam Deepti Roy, Sajitha Remady, Adarsh KS, Jyotsna Kumar

    Published 2024-04-01
    “…European Journal of Medicinal Chemistry Reports…”
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  13. 653
    An overview on natural farnesyltransferase inhibitors for efficient cancer therapy

    An overview on natural farnesyltransferase inhibitors for efficient cancer therapy by Xiaohan Dai, Yingni Sun, Ting Zhang, Yongfei Ming, Gao Hongwei

    Published 2020-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  14. 654
    Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships

    Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships by Marialuigia Fantacuzzi, Ilaria D’Agostino, Simone Carradori, Francesco Liguori, Fabrizio Carta, Mariangela Agamennone, Andrea Angeli, Filomena Sannio, Jean-Denis Docquier, Clemente Capasso, Claudiu T. Supuran

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  15. 655
    Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells

    Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells by Rania H. Abd El-Hameed, Mosaad S. Mohamed, Samir M. Awad, Bardes B. Hassan, Marwa Abd El-Fattah Khodair, Yara E. Mansour

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  16. 656
    Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity

    Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity by Felicia D'Andrea, Stefania Sartini, Ilaria Piano, Matteo Franceschi, Luca Quattrini, Lorenzo Guazzelli, Lidia Ciccone, Elisabetta Orlandini, Claudia Gargini, Concettina La Motta, Susanna Nencetti

    Published 2020-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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  17. 657
    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase by Dres Damgaard, Mads Emil Bjørn, Peter Østrup Jensen, Claus Henrik Nielsen

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  18. 658
    Multicomponent synthesis of some new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki, MDA-MB-231 and SK-Lu-1 tumour cells as apoptosis inducing agents without necrosis

    Multicomponent synthesis of some new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki, MDA-MB-231 and SK-Lu-1 tu... by Sujay Laskar, Luis Sánchez-Sánchez, Manuel López-Ortiz, Hugo López-Muñoz, María L. Escobar-Sánchez, Arturo T. Sánchez, Ignacio Regla

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  19. 659
    Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R

    Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R by Cornelius Hempel, Frank Totzke, Christoph Schächtele, Abdulkarim Najjar, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  20. 660
    Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer’s disease

    Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer’s disease by Wen-Yu Wu, Yu-Chen Dai, Nian-Guang Li, Ze-Xi Dong, Ting Gu, Zhi-Hao Shi, Xin Xue, Yu-Ping Tang, Jin-Ao Duan

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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