Showing 641 - 660 results of 9,722 for search '"medicinal chemistry"', query time: 0.47s Refine Results
  1. 641
    Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core

    Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core by Ravi Tripathi, Abiodun Anifowose, Wen Lu, Xiaoxiao Yang, Binghe Wang

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  2. 642
    Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

    Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities by Zofia Chrienova, Eugenie Nepovimova, Rudolf Andrys, Rafael Dolezal, Jana Janockova, Lubica Muckova, Lenka Fabova, Ondrej Soukup, Patrik Oleksak, Martin Valis, Jan Korabecny, José Marco-Contelles, Kamil Kuca

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  3. 643
    Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation

    Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation by Mohamed Hagras, Moshira A. El Deeb, Heba S. A. Elzahabi, Eslam B. Elkaeed, Ahmed B. M. Mehany, Ibrahim H. Eissa

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  4. 644
    Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors

    Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors by Ibrahim M. Salem, Samia M. Mostafa, Ismail Salama, Osama I. El-Sabbagh, Wael A. H. Hegazy, Tarek S. Ibrahim

    Published 2023-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  5. 645
    Zinc binding groups for histone deacetylase inhibitors

    Zinc binding groups for histone deacetylase inhibitors by Lei Zhang, Jian Zhang, Qixiao Jiang, Li Zhang, Weiguo Song

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  6. 646
    Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents

    Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents by Chao Wang, Yujing Zhang, Lingyu Shi, Shanbo Yang, Jing Chang, Yingjie Zhong, Qian Li, Dongming Xing

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  7. 647
    Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani

    Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani by Alessio Nocentini, Sameh M. Osman, Igor A. Rodrigues, Veronica S. Cardoso, Fatmah Ali S. Alasmary, Zeid AlOthman, Alane B. Vermelho, Paola Gratteri, Claudiu T. Supuran

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  8. 648
    Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents

    Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents by Xian-yu Sun, Chun-yan Zhong, Qing-qing Qiu, Zhen-wang Li, Mei-yu Liu, Xin Wang, Cheng-hao Jin

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  9. 649
    Current trends in silica based drug delivery systems

    Current trends in silica based drug delivery systems by Rozhan Khoz, Fateme Yazdian, Mehrab Pourmadadi, Abbas Rahdar, Sonia Fathi-karkan, Sadanand Pandey

    Published 2024-12-01
    “…European Journal of Medicinal Chemistry Reports…”
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    Article
  10. 650
    Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M

    Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M by Moustafa O. Aboelez, Amany Belal, Guangya Xiang, Xiang Ma

    Published 2022-12-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  11. 651
    Correction to: Inhibitors of alanine racemase enzyme: a review

    Correction to: Inhibitors of alanine racemase enzyme: a review

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  12. 652
    Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis

    Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis by Jiří Dostál, Jiří Brynda, Lucie Vaňková, Syeda Rehana Zia, Iva Pichová, Olga Heidingsfeld, Martin Lepšík

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  13. 653
    Correction to: Synthesis, antitumor screening and cell cycle analysis of novel benzothieno[3,2-b]pyran derivatives

    Correction to: Synthesis, antitumor screening and cell cycle analysis of novel benzothieno[3,2-b]pyran derivatives

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  14. 654
    Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity

    Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity by Simonetta Caira, Antonio Iannelli, Rosaria Sciarrillo, Gianluca Picariello, Giovanni Renzone, Andrea Scaloni, Pietro Addeo

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  15. 655
    Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators

    Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators by Andrea Angeli, Niccolò Chiaramonte, Dina Manetti, Maria Novella Romanelli, Claudiu T. Supuran

    Published 2018-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  16. 656
    Matrine family derivatives: Synthesis, reactions procedures, mechanism, and application in medicinal, agricultural, and materials chemistry

    Matrine family derivatives: Synthesis, reactions procedures, mechanism, and application in medicinal, agricultural, and materials chemistry by Jamal A.H. Kowah, Ruobing Gao, Fu Li, Chenxi Guang, Meiyan Jiang, Xiaolin Wu, Lisheng Wang, Xu Liu

    Published 2023-04-01
    “…European Journal of Medicinal Chemistry Reports…”
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    Article
  17. 657
    Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFRwt-TK inhibitor

    Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFRwt-TK inhibitor by Yaling Zhang, Li Chen, Xiabing Li, Li Gao, Yunxia Hao, Baolin Li, Yaping Yan

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  18. 658
    New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives

    New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives by Olga Ciupak, Mateusz Daśko, Karol Biernacki, Janusz Rachon, Maciej Masłyk, Konrad Kubiński, Aleksandra Martyna, Sebastian Demkowicz

    Published 2021-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  19. 659
    Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase

    Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase by Maria Luisa Di Paolo, Manuela Cervelli, Paolo Mariottini, Alessia Leonetti, Fabio Polticelli, Michela Rosini, Andrea Milelli, Filippo Basagni, Rina Venerando, Enzo Agostinelli, Anna Minarini

    Published 2019-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article
  20. 660
    Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates

    Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates by Alessio Nocentini, Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Fatmah A.S. Alasmary, Zeid AlOthman, Clemente Capasso, Fabrizio Carta, Paola Gratteri, Claudiu T. Supuran

    Published 2017-01-01
    “…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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    Article

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