Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–2 by Diego Muñoz-Torrero, Arduino A. Mangoni, Hong Liu, Christopher Hulme, Jarkko Rautio, Rafik Karaman, Maria Emília de Sousa, Katalin Prokai-Tatrai, Jean-Marc Sabatier, Carlo Siciliano, F. Javier Luque, George Kokotos, Rino Ragno, Simona Collina, Catherine Guillou, Michael Gütschow, Luigi A. Agrofoglio

“…Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of Editorials, which are published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]…”
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Liquid Chromatography on the Different Methods for the Determination of Lipophilicity: An Essential Analytical Tool in Medicinal Chemistry by José X. Soares, Álvaro Santos, Carla Fernandes, Madalena M. M. Pinto

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Development of small molecule CREBBP bromodomain ligands using medicinal chemistry-based approaches by Moroglu, M

“…<p>This work explores medicinal chemistry-based approaches to develop CREBBP bromodomain ligands, using protein-ligand X-ray crystallography to enable structure-guided drug design. …”

4th Russian Conference on Medicinal Chemistry with International Participants «MedChem Russia 2019» by article Editorial

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Machine Learning Application for Medicinal Chemistry: Colchicine Case, New Structures, and Anticancer Activity Prediction by Damian Nowak, Adam Huczyński, Rafał Adam Bachorz, Marcin Hoffmann

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Vascular Endothelial Growth Factor Receptor (VEGFR-2)/KDR Inhibitors: Medicinal Chemistry Perspective by Siddharth J. Modi, Vithal M. Kulkarni

“…The review articles published before were based on the structure and biology of VEGFR-2 rather than medicinal chemistry. While the emphasis of the current review article is to summarise, the recent advancement regarding VEGFR-2 inhibitors concerning medicinal chemistry approaches. …”
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Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents by Rosalba Leuci, Leonardo Brunetti, Antonio Laghezza, Fulvio Loiodice, Paolo Tortorella, Luca Piemontese

“…This review is focused on the significance of zinc (II) chelating agents in past and future medicinal chemistry research, and on the importance of selectivity in order to revamp the possibility of their use in therapy, often hindered by possible side effects.…”
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Approaches to the Potential Therapy of COVID-19: A General Overview from the Medicinal Chemistry Perspective by J. Carlos Menéndez

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Organic dyes in contemporary medicinal chemistry and biomedicine. I. From the chromophore to the bioimaging/bioassay agent by Zvezdelina Yaneva, Donika Ivanova, Nevena Nikolova, Monika Toneva

“…AbstractThe present review was provoked by the demand of a comprehensive overview on the recent scientific achievements revealing new horizons for advanced applications of organic dyes in service of contemporary medicinal chemistry, pharmacy and biomedicine. The review outlines the basic structural characteristics, physicochemical properties and biological activity of various dye families and suggests modified classifications of dyes according to their structural moieties and bioorganic functionalities serving the necessities of modern analytical chemistry and biochemistry. …”
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How Can Deep Eutectic Systems Promote Greener Processes in Medicinal Chemistry and Drug Discovery? by Luis Domingues, Ana Rita C. Duarte, Ana Rita Jesus

“…Chemists in the medicinal chemistry field are constantly searching for alternatives towards more sustainable and eco-friendly processes for the design and synthesis of drug candidates. …”
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From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design by Rita Turnaturi, Silvia Piana, Salvatore Spoto, Giuliana Costanzo, Lorena Reina, Lorella Pasquinucci, Carmela Parenti

“…To optimize their tolerability profiles, medicinal chemistry continues to study novel ligands and innovative approaches. …”
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Selective Ligands for Non-Canonical DNA Structures: Do They Have a Future in Medicinal Chemistry? by Manlio Palumbo, Claudia Sissi

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Comparative Analyses of Medicinal Chemistry and Cheminformatics Filters with Accessible Implementation in Konstanz Information Miner (KNIME) by Sebastjan Kralj, Marko Jukič, Urban Bren

“…We collected the most common filters in medicinal chemistry (PAINS, REOS, Aggregators, van de Waterbeemd, Oprea, Fichert, Ghose, Mozzicconacci, Muegge, Egan, Murcko, Veber, Ro3, Ro4, and Ro5) to facilitate their open access use and compared them. …”
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Team-based learning-adopted strategy in pharmacy education: pharmacology and medicinal chemistry students’ perceptions by Reem T. Attia, Asmaa A. Mandour

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Heteroleptic Copper(I)-Based Complexes Incorporating BINAP and π-Extended Diimines: Synthesis, Catalysis and Biological Applications by Corentin Cruché, Sayak Gupta, Jeremy Kodanko, Shawn K. Collins

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Development of chemical tools to probe the functions of TRIM proteins by Reynolds, J

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Targeting the Ras superfamily via their regulatory GEF complexes by Gray, J

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Characterisation of novel evasins by Eaton, J

Subjects: “…Medicinal Chemistry…”

Boronic acid and nitrofuranyl derivatives as potential therapeutics by Dey, AL

Subjects: “…Medicinal Chemistry…”

Mutate & conjugate: a method for rapid in-cell validation of epigenetic targets by Thomas, AM

Subjects: “…Medicinal chemistry…”