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MicroRNAs in Metastasis and the Tumour Microenvironment
Published 2021-05-01“…Consequently, there is a clear need to better understand metastasis in order to develop new tools to combat this process. MicroRNAs (miRNAs) regulate gene expression and play an important role in cancer development and progression including in the metastatic process. …”
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Circulating microRNAs in Hidradenitis Suppurativa
Published 2022-08-01“…The molecular basis of the inflammatory network remains unclear; however, since microRNAs (miRNAs) are involved in the modulation of inflammation, the composition of a micro-transcriptome RNA library using the blood of HS patients was analysed here. …”
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MicroRNAs in the Regulation of MMPs and Metastasis
Published 2014-03-01Subjects: “…microRNAs…”
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Diagnostic significance of microRNAs in sepsis
Published 2023-01-01“…Many studies have focused on the diagnostic accuracy of microRNAs (miRNAs) for sepsis in recent years, particularly miR-155-5p, miR-21, miR-223-3p, miR-146a, and miR-125a. …”
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Roles of microRNAs in atherosclerosis and restenosis
Published 2012-08-01“…Although the pathophysiological mechanisms underlying atherosclerosis and restenosis have been well established, new signaling molecules that control the progress of these pathologies have continuously been discovered. MicroRNAs (miRs) have recently emerged as a novel class of gene regulators that work via transcriptional degradation and translational inhibition or activation. …”
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Angioregulatory microRNAs in Colorectal Cancer
Published 2019-12-01“…Angiogenesis-related genes can be regulated post-transcriptionally by microRNAs (miRNAs) and some miRNAs have been shown to shuttle between tumor cells and the tumor microenvironment (TME). …”
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107
Exosomal microRNAs in hepatocellular carcinoma
Published 2021-05-01“…In this review, we summarized the composition, active mechanism and function of exosomal microRNAs in hepatocellular carcinoma, and elaborated on their potential application value of early diagnosis and treatment in hepatocellular carcinoma.…”
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microRNAs and Their Roles in Plant Development
Published 2022-02-01“…Small RNAs are short non-coding RNAs with a length ranging between 20 and 24 nucleotides. Of these, microRNAs (miRNAs) play a distinct role in plant development. miRNAs control target gene expression at the post-transcriptional level, either through direct cleavage or inhibition of translation. miRNAs participate in nearly all the developmental processes in plants, such as juvenile-to-adult transition, shoot apical meristem development, leaf morphogenesis, floral organ formation, and flowering time determination. …”
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The world of microRNAs of the hepatobiliary system
Published 2021-03-01“…Changes in some microRNAs in serum or liver tissue have been shown to be highly diagnostic markers of some liver diseases. …”
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Identification of <it>Schistosoma mansoni </it>microRNAs
Published 2011-01-01“…<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs) constitute a class of single-stranded RNAs which play a crucial role in regulating development and controlling gene expression by targeting mRNAs and triggering either translation repression or messenger RNA (mRNA) degradation. miRNAs are widespread in eukaryotes and to date over 14,000 miRNAs have been identified by computational and experimental approaches. …”
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The role of microRNAs in bone metastasis
Published 2016-09-01“…Among the variety of molecules that participate in the metastatic cascade, microRNAs are a class of small non-coding RNA that play an important role in the development of metastatic bone lesions. …”
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MicroRNAs expressed by human cytomegalovirus
Published 2020-03-01“…Abstract Background MicroRNAs (miRNAs) are small non-coding RNAs about 22 nucleotides in length, which play an important role in gene regulation of both eukaryotes and viruses. …”
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MicroRNAs and Apoptosis in Colorectal Cancer
Published 2020-07-01“…Treatment resistance is a major challenge in the development of effective therapies. The microRNAs (miRNAs) play important roles in CRC treatment resistance and CRC progression and apoptosis. …”
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Footprints of microRNAs in Cancer Biology
Published 2021-10-01“…MicroRNAs (miRNAs) are short non-coding RNAs involved in post-transcriptional gene regulation. …”
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MicroRNAs : An Emerging Player In Autophagy
Published 2014-11-01“…A better understanding of interaction between microRNAs and cellular autophagy may ultimately benefit future cancer diagnostic and anticancer therapeutics.…”
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MicroRNAs and Polycystic Kidney Disease
Published 2020-11-01“…Recently, the role of noncoding RNAs, in particular microRNAs, has been described in polycystic kidney diseases. microRNAs are involved in the regulation of gene expression, in which PKD1, PKD2, and other genes that contribute to the pathogenesis of polycystic kidney diseases are considerable participants. …”
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