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17541
Deciphering the role of a miRNA in rice domestication
Published 2017-10-01“…MicroRNAs (miRNAs) are a class of 21 nt non-coding small RNAs (sRNAs) produced from endogenously expressed MIR genes. miRNAs are mostly involved in development and disease resistance. …”
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17542
Quantitative proteomic analysis of gene regulation by miR-34a and miR-34c.
Published 2014-01-01“…microRNAs (miRNAs) repress target genes by destabilizing mRNAs and/or by inhibiting translation. …”
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17543
Extracellular microRNA 3’ end modification across diverse body fluids
Published 2021-09-01“…microRNAs (miRNAs) are small non-coding RNAs that play critical roles in gene regulation. …”
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17544
MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARα and TIMP2
Published 2023-03-01“…MicroRNAs (miRNAs) are small non-coding RNA molecules that bind with the 3′ untranslated regions (UTRs) of genes to regulate expression. …”
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17545
MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies <i>miRNA92a</i> as a Regulator of the <i>LRIG1</i> Stem Cell Gene
Published 2020-04-01“…MicroRNAs (miRNAs) have a critical role in regulating stem cells (SCs) during development, and because aberrant expression of miRNAs occurs in various cancers, our goal was to determine if dysregulation of miRNAs is involved in the SC origin of colorectal cancer (CRC). …”
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17546
miRNA expression profile analysis in kidney of different porcine breeds.
Published 2013-01-01“…microRNAs (miRNAs) are important post-transcriptional regulators in eukaryotes that target mRNAs repressing their expression. …”
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17547
Circulating miRNAs as footprints for liver fibrosis grading in schistosomiasisResearch in context
Published 2018-11-01“…Keywords: Biomarker, schistosome, Schistosoma japonicum, hepatic fibrosis, microRNAs…”
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17548
miR-34c is downregulated in prostate cancer and exerts tumor suppressive functions.
Published 2010“…MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression. …”
Journal article -
17549
Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development
Published 2018“…MicroRNAs (miRNAs) have been shown to be key modulators of post-transcriptional gene silencing in many cellular processes. …”
Journal article -
17550
microRNA as a potential vector for the propagation of robustness in protein expression and oscillatory dynamics within a ceRNA network.
Published 2013-01-01“…microRNAs (miRNAs) are small noncoding RNAs that are important post-transcriptional regulators of gene expression. miRNAs can induce thresholds in protein synthesis. …”
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17551
A genome-wide analysis of the RNA-guided silencing pathway in coffee reveals insights into its regulatory mechanisms.
Published 2017-01-01“…microRNAs (miRNAs) are derived from self-complementary hairpin structures, while small-interfering RNAs (siRNAs) are derived from double-stranded RNA (dsRNA) or hairpin precursors. …”
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17552
Identification of novel miRNAs and miRNA dependent developmental shifts of gene expression in Arabidopsis thaliana.
Published 2010-01-01“…microRNAs (miRNAs) are small, endogenous RNAs of 20 approximately 25 nucleotides, processed from stem-loop regions of longer RNA precursors. …”
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17553
Improving Bioinformatics Prediction of microRNA Targets by Ranks Aggregation
Published 2020-01-01“…microRNAs are noncoding RNAs which downregulate a large number of target mRNAs and modulate cell activity. …”
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17554
SPOROS: A pipeline to analyze DISE/6mer seed toxicity.
Published 2022-03-01“…microRNAs (miRNAs) are (18-22nt long) noncoding short (s)RNAs that suppress gene expression by targeting the 3' untranslated region of target mRNAs. …”
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17555
Sustained Effectiveness and Safety of Therapeutic miR-10a/b in Alleviating Diabetes and Gastrointestinal Dysmotility without Inducing Cancer or Inflammation in Murine Liver and Col...
Published 2024-02-01“…microRNAs (miRNAs) are key regulators of both physiological and pathophysiological mechanisms in diabetes and gastrointestinal (GI) dysmotility. …”
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17556
A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions.
Published 2012-01-01“…microRNAs (miRNAs) are short non-coding RNAs with regulatory functions in various biological processes including cell differentiation, development and oncogenic transformation. …”
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17557
miRLAB: An R Based Dry Lab for Exploring miRNA-mRNA Regulatory Relationships.
Published 2015-01-01“…microRNAs (miRNAs) are important gene regulators at post-transcriptional level, and inferring miRNA-mRNA regulatory relationships is a crucial problem. …”
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17558
miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2.
Published 2012-01-01“…microRNAs (miRNAs) are small noncoding RNAs that regulate genes and contribute to many kinds of human diseases, including cancer. …”
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17559
E2F7 Transcriptionally Inhibits MicroRNA-199b Expression to Promote USP47, Thereby Enhancing Colon Cancer Tumor Stem Cell Activity and Promoting the Occurrence of Colon Cancer
Published 2021-01-01“…microRNAs (miRNAs) can modulate the expression level of genes in a post-transcription manner, which are closely related to growth and metastasis of colon cancer. …”
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17560
The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas.
Published 2009-01-01“…microRNAs (miRNAs) are known to play an essential role in controlling a broad range of biological processes including animal development. …”
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Article