A Machine-learning Approach for the Assessment of the Proliferative Compartment of Solid Tumors on Hematoxylin-Eosin-Stained Sections by Francesco Martino, Silvia Varricchio, Daniela Russo, Francesco Merolla, Gennaro Ilardi, Massimo Mascolo, Giovanni Orabona dell’Aversana, Luigi Califano, Guglielmo Toscano, Giuseppe De Pietro, Maria Frucci, Nadia Brancati, Filippo Fraggetta, Stefania Staibano

“…Finally, we tested our digital framework on a case series of oral squamous cell carcinomas (OSCC), arranged in tissue microarrays; we selected two consecutive sections of each OSCC FFPE TMA (tissue microarray) block, respectively stained with H&E and immuno-stained for Ki67/MIB1. …”
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Cardiovascular Involvement in Pediatric <i>FLNC</i> Variants: A Case Series of Fourteen Patients by Anwar Baban, Viola Alesi, Monia Magliozzi, Giovanni Parlapiano, Silvia Genovese, Marianna Cicenia, Sara Loddo, Valentina Lodato, Luca Di Chiara, Fabiana Fattori, Adele D’Amico, Paola Francalanci, Antonio Amodeo, Antonio Novelli, Fabrizio Drago

“…In one patient, we identified a deletion encompassing <i>FLNC</i> detected by microarray, which was overlooked by next generation sequencing. …”
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Mitochondrial Respiration in Peripheral Blood Mononuclear Cells Negatively Correlates with Disease Severity in Pulmonary Arterial Hypertension by Natascha Sommer, Finn Fabian Theine, Oleg Pak, Khodr Tello, Manuel Richter, Henning Gall, Jochen Wilhelm, Rajkumar Savai, Norbert Weissmann, Werner Seeger, Hossein A. Ghofrani, Matthias Hecker

“…However, when directly comparing mitochondrial respiration to the hemodynamic parameters of an inpatient PAH cohort, mitochondrial respiration negatively correlated with pulmonary vascular resistance (PVR) and positively correlated with the cardiac index (CI). Furthermore, microarray analysis shows upregulation of mitochondrial erythroid-specific 5-aminolevulinate synthase 2 (ALAS2), as well as the regulation of genes involved in iron and heme metabolism, in the PBMC of patients with PAH, with ALAS2 upregulation in PAH patients being confirmed on the protein level. …”
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Expression pattern and diagnostic value of ferroptosis-related genes in acute myocardial infarction by Jiahe Wu, Jiahe Wu, Huanhuan Cai, Huanhuan Cai, Zhe Lei, Zhe Lei, Chenze Li, Chenze Li, Yushuang Hu, Yushuang Hu, Tong Zhang, Tong Zhang, Haoyan Zhu, Haoyan Zhu, Yi Lu, Yi Lu, Jianlei Cao, Jianlei Cao, Xiaorong Hu, Xiaorong Hu

“…Therefore, it is helpful to identify ferroptosis related genes (FRGs) involved in AMI and explore their expression patterns and molecular mechanisms.MethodsThe AMI-related microarray datasets GSE66360 and GSE61144 were obtained using the Gene Expression Omnibus (GEO) online database. …”
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Fetal hyperechoic kidney cohort study and a meta-analysis by Wei Yang, Wei Yang, Shujing Zu, Qiu Jin, Yu Liu, Chao Wang, Huimin Shen, Ruijing Wang, Hui Zhang, Meimei Liu

“…The positive rate of (chromosome microarray analysis) CMA in IHK was 59% and that in NIHK was 32%, with the ORs of 1.46 (95% CI 1.33–1.62) and 0.48 (95% CI, 0.28–0.85), respectively. …”
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Predictive model, miRNA-TF network, related subgroup identification and drug prediction of ischemic stroke complicated with mental disorders based on genes related to gut microbiom... by Jing Shen, Yu Feng, Yu Feng, Minyan Lu, Jin He, Huifeng Yang

“…Five genes related to mental disorders and GM were extracted from Gene cards and other databases. Linear models for microarray data (Limma) analysis was utilized to identify differentially expressed genes (DEGs) and perform functional enrichment analysis. …”
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Identification of potential therapeutic targets for COVID-19 through a structural-based similarity approach between SARS-CoV-2 and its human host proteins by Alvea Tasneem, Armiya Sultan, Prithvi Singh, Hridoy R. Bairagya, Hassan Hussain Almasoudi, Abdulfattah Yahya M. Alhazmi, Abdulkarim S. Binshaya, Mohammed Ageeli Hakami, Bader S. Alotaibi, Alaa Abdulaziz Eisa, Abdulaziz Saleh I. Alolaiqy, Mohammad Raghibul Hasan, Kapil Dev, Ravins Dohare

“…Structure-based virtual screening with antiviral compounds was performed to identify potential hits against target gene-encoded protein.Results: This study predicted 19,051 unique target human proteins that interact with hCoV-2, and compared to the microarray dataset, 1,120 target and infected group differentially expressed genes (TIG-DEGs) were identified. …”
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Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families by Isaac Baldwin, Robin L. Shafer, Waheeda A. Hossain, Sumedha Gunewardena, Olivia J. Veatch, Matthew W. Mosconi, Merlin G. Butler

“…The 15q11.2 BP1-BP2 deletion (Burnside-Butler) syndrome is emerging as the most common cytogenetic finding in patients with neurodevelopmental or autism spectrum disorders (ASD) presenting for microarray genetic testing. Clinical findings in Burnside-Butler syndrome include developmental and motor delays, congenital abnormalities, learning and behavioral problems, and abnormal brain findings. …”
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Significant Enrichment and Diversity of the Staphylococcal Arginine Catabolic Mobile Element ACME in Staphylococcus epidermidis Isolates From Subgingival Peri-implantitis Sites and... by Aoife M. O’Connor, Brenda A. McManus, Peter M. Kinnevey, Gráinne I. Brennan, Tanya E. Fleming, Phillipa J. Cashin, Michael O’Sullivan, Ioannis Polyzois, David C. Coleman

“…The arginine catabolic mobile element (ACME), thought to enhance colonization and survival of S. aureus, was detected in 100/179 S. epidermidis and 0/83 S. aureus isolates screened using multiplex PCR and DNA microarray profiling. Five distinct ACME types, including the recently described types IV and V (I; 14, II; 60, III; 10, IV; 15, V; 1) were identified. …”
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Effects of progesterone concentrations and follicular wave during growth of the ovulatory follicle on conceptus and endometrial transcriptome in dairy cows by R.S. Bisinotto, E.S. Ribeiro, L.F. Greco, D. Taylor-Rodriguez, A.D. Ealy, H. Ayres, F.S. Lima, N. Martinez, W.W. Thatcher, J.E.P. Santos

“…Transcriptome was evaluated by microarray using the Affymetrix Bovine Array. Orthogonal contrasts were built to assess the effects of progesterone concentration during follicle growth (FW vs. …”
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The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs by Roberto Stabile, Mario Román Cabezas, Mathijs P. Verhagen, Francesco A. Tucci, Thierry P. P. van den Bosch, Maria J. De Herdt, Berdine van der Steen, Alex L. Nigg, Meng Chen, Cristina Ivan, Masayoshi Shimizu, Senada Koljenović, Jose A. Hardillo, C. Peter Verrijzer, Robert J. Baatenburg de Jong, George A. Calin, Riccardo Fodde

“…We also developed a novel approach to the combined ISH/IF tissue microarray analysis to study the expression patterns of miRs and their target genes in the context of tumor architecture. …”
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Homogeneity in immune features between colorectal liver metastases better identifies patients with good prognosis compared to pathological response to preoperative chemotherapy by David Henault, David Stephen, Pierre-Antoine St-Hilaire, Nouredin Messaoudi, Franck Vandenbroucke-Menu, Eve Simoneau, Zhixia Rong, Marylène Plasse, Richard Létourneau, André Roy, Michel Dagenais, Réal Lapointe, Bich Nguyen, Anne-Marie Mes-Masson, G. Soucy, Simon Turcotte

“…However, the prognostic significance of the heterogeneity of these features in patients with multiple CRLMs remains under investigation. We used a tissue microarray of 220 mismatch repair-gene proficient CRLMs resected in 97 patients followed prospectively to quantify CD3+ T cells and MHC-I by immunohistochemistry. …”
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Transcriptomic meta‐analysis of disuse muscle atrophy vs. resistance exercise‐induced hypertrophy in young and older humans by Colleen S. Deane, Craig R.G. Willis, Bethan E. Phillips, Philip J. Atherton, Lorna W. Harries, Ryan M. Ames, Nathaniel J. Szewczyk, Timothy Etheridge

“…Methods Integrated gene‐level and network‐level meta‐analysis was performed on publicly available microarray data sets generated from young (18–35 years) m. vastus lateralis muscle subjected to disuse (unilateral limb immobilization or bed rest) lasting ≥7 days or RET lasting ≥3 weeks, and resistance‐trained older (≥60 years) muscle. …”
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Predictive and Prognostic Significance of mRNA Expression and DNA Copies Aberrations of <i>ERCC1</i>, <i>RRM1</i>, <i>TOP1</i>, <i>TOP2A</i>, <i>TUBB3</i>, <i>TYMS</i>, and <i>GSTP... by Matvey M. Tsyganov, Marina K. Ibragimova, Evgeniy Yu. Garbukov, Irina A. Tsydenova, Kseniya A. Gaptulbarova, Daria S. Dolgasheva, Ekaterina A. Zdereva, Anastasia A. Frolova, Elena M. Slonimskaya, Nikolai V. Litviakov

“…DNA and RNA were isolated from samples of tumor tissue before and after treatment. Microarray analysis was performed for all samples on high-density microarrays (DNA chips) of Affymetrix (USA) CytoScanTM HD Array and Clariom™ S Assay, human. …”
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Bone-Metabolism-Related Serum microRNAs to Diagnose Osteoporosis in Middle-Aged and Elderly Women by Sheng-Li Zhao, Zhen-Xing Wen, Xiao-Yi Mo, Xiao-Yan Zhang, Hao-Nan Li, Wing-Hoi Cheung, Dan Fu, Shi-Hong Zhang, Yong Wan, Bai-Ling Chen

“…The miRNA expression profiles in the serum of PMOP patients were evaluated via miRNA microarray (six PMOP patients and four postmenopausal women without osteoporosis (n-PMOP) as controls). …”
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Construction of Potential Glioblastoma Multiforme-Related miRNA-mRNA Regulatory Network by Weiyang Lou, Weiyang Lou, Weiyang Lou, Bisha Ding, Bisha Ding, Bisha Ding, Liang Xu, Liang Xu, Liang Xu, Weimin Fan, Weimin Fan, Weimin Fan, Weimin Fan

“…However, a comprehensive miRNA-mRNA regulatory network has still not been established.Methods: A miRNA microarray dataset (GSE90603) was obtained from GEO database. …”
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Carbon nanotube-based optical sensors for pharmaceutical applications : theory and experiment by Salem, Daniel P. (Daniel Parker)

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Molecular pathogenesis of Helicobacter hepaticus induced liver disease by Boutin, Samuel R., 1952-

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Regulation of Drosophila eye development by the transcription factors : eyes absent and Spenito by Jemc, Jennifer Colleen

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Genes implicated in phorbol ester (PE) biosynthesis and interception through downregulation of casbene synthase genes by Ng, Ailing

“…A boutique array consisting of 112 candidate genes was constructed using an in house microarray facility. Expression level of these genes in subjects that have high PE content was compared against embryo and cotyledon that has non-detectable PE level. …”
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