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8181
GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma
Published 2023-02-01“…Methods: Gene expression microarrays, flow cytometry, western blot, qRT-PCR, immunohistochemistry and immunofluorescence were used to study the response of HCC cells to lenvatinib. …”
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Article -
8182
Synergy of the microRNA Ratio as a Promising Diagnosis Biomarker for Mucinous Borderline and Malignant Ovarian Tumors
Published 2023-11-01“…In this study, the comparison of miRNA microarray expression profiles between malignant and borderline tumor FFPE samples identified 10 down-regulated and 5 up-regulated malignant miRNAs, which were validated by individual RT-qPCR. …”
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Article -
8183
Positive regulation of innate immune response by miRNA-let-7a-5p
Published 2023-01-01“…In this study, to investigate the pathogenesis of AD with and without severe ACD, we performed comprehensive plasma miRNA analysis and studied the function of some miRNAs which were significantly up-regulated in ACD.Methods: Transcriptomics analysis of miRNA was performed using the microarray platform from the plasma of nine individuals (AD, severe ACD, controls: n = 3 each). …”
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8184
Variants of Streptococcus pneumoniae Serotype 14 from Papua New Guinea with the Potential to Be Mistyped and Escape Vaccine-Induced Protection
Published 2022-08-01“…Swabs containing pneumococci (n = 1,226) were serotyped by microarray to identify pneumococci with a divergent serotype 14 capsule locus. …”
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8185
Proteoglycans: Systems-Level Insight into Their Expression in Healthy and Diseased Placentas
Published 2022-05-01“…To fill this gap, herein, we provide an overview of the proteoglycans’ expression and role in the placenta, in trophoblast development, and in pregnancy complications (pre-eclampsia, fetal growth restriction), highlighting one of the most important members of this family, syndecan-1 (<i>SDC1</i>). Microarray data analysis showed that of 34 placentally expressed proteoglycans, <i>SDC1</i> production is markedly the highest in the placenta and that <i>SDC1</i> is the most upregulated gene during trophoblast differentiation into the syncytiotrophoblast. …”
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Article -
8186
The Oncogenic and Tumor Suppressive Long Non-Coding RNA–microRNA–Messenger RNA Regulatory Axes Identified by Analyzing Multiple Platform Omics Data from Cr(VI)-Transformed Cells an...
Published 2022-09-01“…To explore the mechanism of Cr(VI) lung carcinogenesis, we performed lncRNA, mRNA, and miRNA microarray analysis using total RNAs from our previously established chronic Cr(VI) exposure malignantly transformed and passage-matched control human bronchial epithelial BEAS-2B cells. …”
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8187
LINC00173 facilitates tumor progression by stimulating RAB1B‐mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma
Published 2023-03-01“…An increasing number of studies have found that long non‐coding RNA (lncRNA) play important roles in driving the progression of nasopharyngeal carcinoma (NPC). Our microarray screening revealed that expression of the lncRNA long intergenic non‐protein coding RNA 173 (LINC00173) was upregulated in NPC. …”
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Article -
8188
Urinary MicroRNAs of Prostate Cancer: Virus-Encoded hsv1-miRH18 and hsv2-miR-H9-5p Could Be Valuable Diagnostic Markers
Published 2015-06-01“…A urine-based miRNA microarray analysis suggested the presence of differentially expressed urinary miRNAs in patients with PCa, and these were further validated in three independent PCa cohorts, using a quantitative reverse transcriptionpolymerase chain reaction analysis. …”
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8189
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8190
Smart surfaces using functional polymer brushes prepared via organocatalyzed living radical polymerization
Published 2024“…Such rewritable smart surfaces may be exploited for rewritable microarray technologies and sensing interfaces. Chapter 4 presents the syntheses of an AIE-bearing fluorescent polymer brush, i.e., poly(4-(1,2,2-triphenylvinyl)phenyl methacrylate) polymer brush. …”
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Thesis-Doctor of Philosophy -
8191
Fast and scalable data mining algorithms for clustering using graphics processors
Published 2014“…Astounding speed gains up to 140 times on GPU 8800GTX and up to 73 times on GPU 8500GT are realized using real-life microarray gene expressions. In the third part of this thesis, we explore the use of Nvidia’s Compute Unified Device Architecture (CUDA) based framework to develop efficient low-cost, high performance implementation of the Hierarchical Agglomerative Clustering (HAC) and Partially Overlapping Partitioning (PoP) based HAC on the GPU. …”
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Thesis -
8192
Meta-cognitive sequential learning in RBF network for diagnosis of neurodegenerative diseases
Published 2014“…PBL-McRBFN classifier is used to predict PD using microarray gene expression data. Next, PBL-McRBFN classifier is used to predict PD from MRI scans. …”
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Thesis -
8193
Mechanism of anti-cancer activity of (z)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenylprop–2–en-1-one (DK1) in human osteosarcoma cells and subchronic toxicity evaluation in BALB/C mice...
Published 2021“…Additionally, DK1 also possessed an anti-angiogenic potential that was proven by the finding that the percentage of tube formation and microvessels sprouting were significantly (p<0.05) reduced. From the microarray analysis several cancer pathways such as PI3K/Akt, MAPK, NF-κB, P53 and cell cycle were successfully modulated by the DK1. …”
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Thesis -
8194
Gli1-mediated tumor cell-derived bFGF promotes tumor angiogenesis and pericyte coverage in non-small cell lung cancer
Published 2024-03-01“…Angiogenic antibody microarray analysis, ELISA, luciferase reporte, chromatin immunoprecipitation (ChIP), bFGF protein stability and ubiquitination assay were performed to explore how Gli1 regulate bFGF expression. …”
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Article -
8195
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop
Published 2022-02-01“…Methods Strand‐specific RNA‐sequencing (RNA‐seq) and microarray datasets were used to profile the dynamic circRNAome landscape during skeletal muscle development and myogenic differentiation. …”
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Article -
8196
Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples
Published 2023-06-01“…Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters. Chromosomal microarray (CMA) and rapid aneuploidy detection (QF-PCR and FISH) were performed on placental villi and uncultured amniotic fluid. …”
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Article -
8197
A novel lncRNA FPASL regulates fibroblast proliferation via the PI3K/AKT and MAPK signaling pathways in hypertrophic scar
Published 2022-09-01“…In this study, a novel fibroblast proliferation-associated lncRNA, named lncRNA FPASL (MSTRG.389905.1), which is mainly localized in the cytoplasm, is found to be downregulated in hypertrophic scar, as detected by lncRNA microarray and qRT-PCR. The full-length FPASL is characterized and further investigation confirms that it has no protein-coding potential. …”
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Article -
8198
Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma
Published 2024-01-01“…In addition, tissue microarray (TMA) and immunohistochemistry (IHC) staining were performed on 228 samples of PDAC tissue and 10 samples of normal pancreatic tissue to assess the expression levels of the markers. …”
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Article -
8199
Utilizing Andrographis paniculata leaves and roots by effective usage of the bioactive andrographolide and its nanodelivery: investigation of antikindling and antioxidant activitie...
Published 2023-05-01“…In this study, we used GSE28674 as a microarray expression profiling dataset to identify DEGs associated with andrographolide and those with fold changes >1 and p-value <0.05 GEO2R. …”
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Article -
8200
FLI1 regulates radiotherapy resistance in nasopharyngeal carcinoma through TIE1-mediated PI3K/AKT signaling pathway
Published 2023-02-01“…Gene expression with clinical information from tissue microarray of NPC were analyzed for associations between FLI1/TIE1 expression and NPC prognosis. …”
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Article