GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma by Wenliang Tan, Kelin Zhang, Xinming Chen, Lei Yang, Sicong Zhu, Yingcheng Wei, Zhiqin Xie, Yajin Chen, Changzhen Shang

“…Methods: Gene expression microarrays, flow cytometry, western blot, qRT-PCR, immunohistochemistry and immunofluorescence were used to study the response of HCC cells to lenvatinib. …”
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Synergy of the microRNA Ratio as a Promising Diagnosis Biomarker for Mucinous Borderline and Malignant Ovarian Tumors by Enora Dolivet, Léopold Gaichies, Corinne Jeanne, Céline Bazille, Mélanie Briand, Mégane Vernon, Florence Giffard, Frédéric Leprêtre, Laurent Poulain, Christophe Denoyelle, Nicolas Vigneron, Raffaèle Fauvet

“…In this study, the comparison of miRNA microarray expression profiles between malignant and borderline tumor FFPE samples identified 10 down-regulated and 5 up-regulated malignant miRNAs, which were validated by individual RT-qPCR. …”
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Positive regulation of innate immune response by miRNA-let-7a-5p by Mayumi Ueta, Hiromi Nishigaki, Seitaro Komai, Katsura Mizushima, Risa Tamagawa-Mineoka, Yuji Naito, Norito Katoh, Chie Sotozono, Shigeru Kinoshita

“…In this study, to investigate the pathogenesis of AD with and without severe ACD, we performed comprehensive plasma miRNA analysis and studied the function of some miRNAs which were significantly up-regulated in ACD.Methods: Transcriptomics analysis of miRNA was performed using the microarray platform from the plasma of nine individuals (AD, severe ACD, controls: n = 3 each). …”
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Variants of Streptococcus pneumoniae Serotype 14 from Papua New Guinea with the Potential to Be Mistyped and Escape Vaccine-Induced Protection by Sam Manna, Leena Spry, Ashleigh Wee-Hee, Belinda D. Ortika, Laura K. Boelsen, Steven Batinovic, Nadia Mazarakis, Rebecca L. Ford, Stephanie W. Lo, Stephen D. Bentley, Fiona M. Russell, Christopher C. Blyth, William S. Pomat, Steve Petrovski, Jason Hinds, Paul V. Licciardi, Catherine Satzke

“…Swabs containing pneumococci (n = 1,226) were serotyped by microarray to identify pneumococci with a divergent serotype 14 capsule locus. …”
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Proteoglycans: Systems-Level Insight into Their Expression in Healthy and Diseased Placentas by Orsolya Oravecz, Andrea Balogh, Roberto Romero, Yi Xu, Kata Juhasz, Zsolt Gelencser, Zhonghui Xu, Gaurav Bhatti, Roger Pique-Regi, Balint Peterfia, Petronella Hupuczi, Ilona Kovalszky, Padma Murthi, Adi L. Tarca, Zoltan Papp, Janos Matko, Nandor Gabor Than

“…To fill this gap, herein, we provide an overview of the proteoglycans’ expression and role in the placenta, in trophoblast development, and in pregnancy complications (pre-eclampsia, fetal growth restriction), highlighting one of the most important members of this family, syndecan-1 (<i>SDC1</i>). Microarray data analysis showed that of 34 placentally expressed proteoglycans, <i>SDC1</i> production is markedly the highest in the placenta and that <i>SDC1</i> is the most upregulated gene during trophoblast differentiation into the syncytiotrophoblast. …”
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The Oncogenic and Tumor Suppressive Long Non-Coding RNA–microRNA–Messenger RNA Regulatory Axes Identified by Analyzing Multiple Platform Omics Data from Cr(VI)-Transformed Cells an... by Osama Sweef, Chengfeng Yang, Zhishan Wang

“…To explore the mechanism of Cr(VI) lung carcinogenesis, we performed lncRNA, mRNA, and miRNA microarray analysis using total RNAs from our previously established chronic Cr(VI) exposure malignantly transformed and passage-matched control human bronchial epithelial BEAS-2B cells. …”
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LINC00173 facilitates tumor progression by stimulating RAB1B‐mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma by Shi‐Wei He, Ye‐Lin Liang, Yuan Zhang, Xu Liu, Sha Gong, Ming‐Liang Ye, Sheng‐Yan Huang, Xi‐Rong Tan, Shi‐Qing Zhou, Yin Zhao, Na Liu, Ying‐Qing Li

“…An increasing number of studies have found that long non‐coding RNA (lncRNA) play important roles in driving the progression of nasopharyngeal carcinoma (NPC). Our microarray screening revealed that expression of the lncRNA long intergenic non‐protein coding RNA 173 (LINC00173) was upregulated in NPC. …”
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Urinary MicroRNAs of Prostate Cancer: Virus-Encoded hsv1-miRH18 and hsv2-miR-H9-5p Could Be Valuable Diagnostic Markers by Seok Joong Yun, Pildu Jeong, Ho Won Kang, Ye-Hwan Kim, Eun-Ah Kim, Chunri Yan, Young-Ki Choi, Dongho Kim, Jung Min Kim, Seon-Kyu Kim, Seon-Young Kim, Sang Tae Kim, Won Tae Kim, Ok-Jun Lee, Gou-Young Koh, Sung-Kwon Moon, Isaac Yi Kim, Jayoung Kim, Yung-Hyun Choi, Wun-Jae Kim

“…A urine-based miRNA microarray analysis suggested the presence of differentially expressed urinary miRNAs in patients with PCa, and these were further validated in three independent PCa cohorts, using a quantitative reverse transcriptionpolymerase chain reaction analysis. …”
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Discovery of miRNA-regulated processes in mammalian development by Young, Amanda Garfinkel

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Smart surfaces using functional polymer brushes prepared via organocatalyzed living radical polymerization by Sim, Xuan Ming

“…Such rewritable smart surfaces may be exploited for rewritable microarray technologies and sensing interfaces. Chapter 4 presents the syntheses of an AIE-bearing fluorescent polymer brush, i.e., poly(4-(1,2,2-triphenylvinyl)phenyl methacrylate) polymer brush. …”
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Fast and scalable data mining algorithms for clustering using graphics processors by Salli Aruliah Arul Shalom.

“…Astounding speed gains up to 140 times on GPU 8800GTX and up to 73 times on GPU 8500GT are realized using real-life microarray gene expressions. In the third part of this thesis, we explore the use of Nvidia’s Compute Unified Device Architecture (CUDA) based framework to develop efficient low-cost, high performance implementation of the Hierarchical Agglomerative Clustering (HAC) and Partially Overlapping Partitioning (PoP) based HAC on the GPU. …”
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Meta-cognitive sequential learning in RBF network for diagnosis of neurodegenerative diseases by Giduthuri Sateesh Babu

“…PBL-McRBFN classifier is used to predict PD using microarray gene expression data. Next, PBL-McRBFN classifier is used to predict PD from MRI scans. …”
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Mechanism of anti-cancer activity of (z)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenylprop–2–en-1-one (DK1) in human osteosarcoma cells and subchronic toxicity evaluation in BALB/C mice... by Aziz, Muhammad Nazirul Mubin

“…Additionally, DK1 also possessed an anti-angiogenic potential that was proven by the finding that the percentage of tube formation and microvessels sprouting were significantly (p<0.05) reduced. From the microarray analysis several cancer pathways such as PI3K/Akt, MAPK, NF-κB, P53 and cell cycle were successfully modulated by the DK1. …”
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Gli1-mediated tumor cell-derived bFGF promotes tumor angiogenesis and pericyte coverage in non-small cell lung cancer by Xueping Lei, Zhan Li, Manting Huang, Lijuan Huang, Yong Huang, Sha Lv, Weisong Zhang, Zhuowen Chen, Yuanyu Ke, Songpei Li, Jingfei Chen, Xiangyu Yang, Qiudi Deng, Junshan Liu, Xiyong Yu

“…Angiogenic antibody microarray analysis, ELISA, luciferase reporte, chromatin immunoprecipitation (ChIP), bFGF protein stability and ubiquitination assay were performed to explore how Gli1 regulate bFGF expression. …”
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circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop by Junyu Yan, Yalan Yang, Xinhao Fan, Guoming Liang, Zishuai Wang, Jiju Li, Liyuan Wang, Yun Chen, Adeyinka Abiola Adetula, Yijie Tang, Kui Li, Dazhi Wang, Zhonglin Tang

“…Methods Strand‐specific RNA‐sequencing (RNA‐seq) and microarray datasets were used to profile the dynamic circRNAome landscape during skeletal muscle development and myogenic differentiation. …”
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Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples by Lingping Li, Lingping Li, Lingping Li, Xijing Liu, Xijing Liu, Xijing Liu, Qinqin Li, Qinqin Li, Qinqin Li, Lili Zhang, Lili Zhang, Lili Zhang, Yueyue Xiong, Yueyue Xiong, Yueyue Xiong, Shanling Liu, Shanling Liu, Shanling Liu, He Wang, He Wang, He Wang, Hongmei Zhu, Hongmei Zhu, Hongmei Zhu, Xuemei Zhang, Xuemei Zhang, Xuemei Zhang

“…Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid.Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters. Chromosomal microarray (CMA) and rapid aneuploidy detection (QF-PCR and FISH) were performed on placental villi and uncultured amniotic fluid. …”
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A novel lncRNA FPASL regulates fibroblast proliferation via the PI3K/AKT and MAPK signaling pathways in hypertrophic scar by Ma Fang, Shen Jiangyong, Zhang Hui, Zhang Zhenghao, Yang Anning, Xiong Jiantuan, Jiao Yun, Bai Zhigang, Ma Shengchao, Zhang Huiping, Jiang Yideng

“…In this study, a novel fibroblast proliferation-associated lncRNA, named lncRNA FPASL (MSTRG.389905.1), which is mainly localized in the cytoplasm, is found to be downregulated in hypertrophic scar, as detected by lncRNA microarray and qRT-PCR. The full-length FPASL is characterized and further investigation confirms that it has no protein-coding potential. …”
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Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma by Fereshteh Rezagholizadeh, Fereshteh Rezagholizadeh, Fereshteh Rezagholizadeh, Fatemeh Tajik, Morteza Talebi, Morteza Talebi, Morteza Talebi, Seyed Reza Taha, Mahdieh Shariat Zadeh, Pooya Farhangnia, Pooya Farhangnia, Pooya Farhangnia, Hamideh Sadat Hosseini, Aram Nazari, Aram Nazari, Shabnam Mollazadeh Ghomi, Shabnam Mollazadeh Ghomi, Shabnam Mollazadeh Ghomi, Seyede Mahtab Kamrani Mousavi, Seyede Mahtab Kamrani Mousavi, Niloofar Haeri Moghaddam, Niloofar Haeri Moghaddam, Hossein Khorramdelazad, Hossein Khorramdelazad, Mohammad Taghi Joghataei, Mohammad Taghi Joghataei, Elahe Safari, Elahe Safari

“…In addition, tissue microarray (TMA) and immunohistochemistry (IHC) staining were performed on 228 samples of PDAC tissue and 10 samples of normal pancreatic tissue to assess the expression levels of the markers. …”
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Utilizing Andrographis paniculata leaves and roots by effective usage of the bioactive andrographolide and its nanodelivery: investigation of antikindling and antioxidant activitie... by Ramana Baru Venkata, Dintakurthi Sree Naga Bala Krishna Prasanth, Praveen Kumar Pasala, Siva Prasad Panda, Vinay Bharadwaj Tatipamula, Sirisha Mulukuri, Ravi Kumar Kota, Mithun Rudrapal, Johra Khan, Johra Khan, Sahar Aldosari, Sahar Aldosari, Bader Alshehri, Bader Alshehri, Saeed Banawas, Saeed Banawas, Saeed Banawas, Madhusudan Chetty Challa, Jithendra Kumar Kammili

“…In this study, we used GSE28674 as a microarray expression profiling dataset to identify DEGs associated with andrographolide and those with fold changes &gt;1 and p-value &lt;0.05 GEO2R. …”
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FLI1 regulates radiotherapy resistance in nasopharyngeal carcinoma through TIE1-mediated PI3K/AKT signaling pathway by Enni Chen, Jiajia Huang, Miao Chen, Jiawei Wu, Puyun Ouyang, Xiaonan Wang, Dingbo Shi, Zhiqiao Liu, Wancui Zhu, Haohui Sun, Shanshan Yang, Baoyu Zhang, Wuguo Deng, Huijuan Qiu, Fangyun Xie

“…Gene expression with clinical information from tissue microarray of NPC were analyzed for associations between FLI1/TIE1 expression and NPC prognosis. …”
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