-
8541
Mucosal circadian rhythm pathway genes altered by aging and periodontitis.
Published 2022-01-01“…Gingival tissue samples were obtained from healthy, diseased, and resolved sites in four groups: young (≤3 years), adolescent (3-7 years), adult (12-26) and aged (18-23 years). Microarrays targeted circadian rhythm (n = 42), inflammation/tissue destruction (n = 11), bone biology (n = 8) and hypoxia pathway (n = 7) genes.…”
Get full text
Article -
8542
A Literature Review to Evaluate the Impact of Machine Learning and Artificial Intelligence for Lung Cancer Patient in COVID-19 Pandemic
Published 2024-01-01“…Artificial intelligence and machine learning can be used to predict lung cancer using data from microarrays, pictures, and other sources. Limited data on COVID-19 patients with a relatively small sample, information regarding the implementation of machine learning and artificial intelligence for the treatment of COVID-19 patients with lung cancer is still limited. …”
Get full text
Article -
8543
A novel technique for measuring variations in DNA copy-number: competitive genomic polymerase chain reaction
Published 2007-07-01“…Characterization of these changes is important for both basic understanding and diagnosis of these diseases. Microarrays have recently become the standard technique and are commercially available. …”
Get full text
Article -
8544
Identification and Characterization of als Genes Involved in D-Allose Metabolism in Lineage II Strain of Listeria monocytogenes
Published 2018-04-01“…Recombinant strain ICDC-LM188 containing these genes showed utilization of D-allose by growth assays and Biolog phenotype microarrays. Moreover, lmo0734 to 0736 were verified to be essential for D-allose metabolism, lmo0737 and 0738 affected the growth rate of L. monocytogenes in D-allose medium, while lmo0739 was dispensable in the metabolism of D-allose in L. monocytogenes. …”
Get full text
Article -
8545
The roles of long noncoding RNA-mediated macrophage polarization in respiratory diseases
Published 2023-01-01“…In recent decades, with the advent of broad-range profiling methods such as microarrays and next-generation sequencing, the discovery of RNA transcripts that do not encode proteins termed “noncoding RNAs (ncRNAs)” has become more easily accessible. …”
Get full text
Article -
8546
Transcriptional Basis of Psoriasis from Large Scale Gene Expression Studies: The Importance of Moving towards a Precision Medicine Approach
Published 2022-05-01“…Transcriptome profiling techniques, such as microarrays and RNA sequencing (RNA-seq), are valuable tools for deciphering the regulatory network underlying psoriasis and have revealed large number of differentially expressed genes in lesional and non-lesional skin. …”
Get full text
Article -
8547
What Can We Learn from -Omics Approaches to Understand Clubroot Disease?
Published 2022-06-01“…While only a few proteome studies and metabolome analyses were performed, the majority of studies used microarrays and RNAseq approaches to study transcriptomes. …”
Get full text
Article -
8548
Validation Processes of Protein Biomarkers in Serum—A Cross Platform Comparison
Published 2012-09-01“…This review will focus on three main multi-analyte immunoassay platforms: planar microarrays, multiplex bead systems and, array-based surface plasmon resonance (SPR) chips. …”
Get full text
Article -
8549
Milk production in the post-genomic era
Published 2004-12-01“…The availability of genomic DNA sequences for a number of potential candidate genes with an impact on production traits allowed construction of cattle genome microarrays. Functional studies of milk protein genes revealed the impact of different genetic variants on technological properties of milk. …”
Get full text
Article -
8550
microRNA-203 inhibits migration and invasion of canine tonsillar squamous cell carcinoma cells by targeting SLUG
Published 2023-08-01“…This study aimed to elucidate the molecular mechanisms underlying the migration and invasion of TSCC cells in vitro.Materials and methodsThis study focused on differential microRNA (miRNA) expression using microRNA microarrays and quantitative polymerase chain reaction in canine TSCC and NTSCC tissues and cell lines. …”
Get full text
Article -
8551
DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast.
Published 2013-01-01“…Using chromatin immunoprecipitation and tiling microarrays, we show that Top3, unlike Top1 and Top2, is highly enriched at centromeric central domains, demonstrating that Top3 is the major topoisomerase in this region. …”
Get full text
Article -
8552
Role of microRNA in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH): a comprehensive review
Published 2023-09-01“…The results from the present review imply that miRNA microarrays and sequencing may be helpful diagnostic tools, and miRNAs may be a possible treatment target for patients with NAFLD.…”
Get full text
Article -
8553
PRR11 Is a Prognostic Marker and Potential Oncogene in Patients with Gastric Cancer.
Published 2015-01-01“…PRR11 was found to be overexpressed in 107 (49.5%) patients by immunohistochemistry of tissue microarrays generated using the patient samples. Furthermore, PRR11 overexpression was found to correlate significantly with clinicopathologic features such as tumor invasion, tumor differentiation, and disease stage. …”
Get full text
Article -
8554
Genetic Reprogramming of Human Mammary Cells by Environmental Carcinogens Released into Breast Milk
Published 2008-05-01“…High-density oligonucleotide microarrays were used to monitor global transcriptional profiles in a human cell line (MCF7) that represents one of the most frequently used model systems to study breast cancer biology. …”
Get full text
Article -
8555
DNA topoisomerase IIα and mitosin expression predict meningioma recurrence better than histopathological grade and MIB-1 after initial surgery.
Published 2017-01-01“…METHODS:The expression of MIB-1, topoisomerase IIα, and mitosin were determined as proliferation indices in tissue microarrays using immunohistochemistry. The accuracy of prognostication was assessed with receiver operating characteristic (ROC) analyses and standard survival analyses. …”
Get full text
Article -
8556
Diagnostically misleading aberrant terminal deoxynucleotidyl transferase expression in germ cell tumors
Published 2022-10-01“…We included 173 cases of testicular GCTs, 5 ovarian dysgerminomas, and one gonadoblastoma in the study. Tissue microarrays containing representative tumor samples were constructed and subsequently stained with anti-TdT monoclonal rabbit antibody EP266 (Dako) and TdT rabbit polyclonal antibody (Cell Marque). …”
Get full text
Article -
8557
Expression of EMP 1, 2, and 3 in Adrenal Cortical Neoplasm and Pheochromocytoma
Published 2023-08-01“…The purpose of this study is to investigate the expression of the epithelial membrane proteins (EMP) 1, 2, and 3 in adrenal gland neoplasm and to explore the broader implications of this. Tissue microarrays were constructed for 132 cases of adrenal cortical neoplasms (ACN) (adrenal cortical adenoma (115 cases), and carcinoma (17 cases)) and 189 cases of pheochromocytoma. …”
Get full text
Article -
8558
Measuring Escherichia coli Gene Expression during Human Urinary Tract Infections
Published 2016-01-01“…To answer this question, we examined the transcriptome of E. coli CFT073 in the murine model of urinary tract infection (UTI) as well as for E. coli strains collected and analyzed directly from the urine of patients attending either a urology clinic or a university health clinic for symptoms of UTI. Using microarrays and RNA-seq, we measured in vivo gene expression for these uropathogenic E. coli strains, identifying genes upregulated during murine and human UTI. …”
Get full text
Article -
8559
Studying Müllerian duct anomalies - from cataloguing phenotypes to discovering causation
Published 2021“…The current knowledge in this field predominantly derives from loss-of-function experiments in mouse and chicken models, as well as from human genetic association studies using traditional approaches, such as microarrays and Sanger sequencing, limiting the discovery of causal factors to few genetic entities from the coding genome. …”
Journal article -
8560
Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle.
Published 2003“…Here we examined the expression patterns of synchronized HeLa cells in G1 or G2, after exposure to 2Gy of X-rays on microarrays allowing evaluation of over 12,000 human genes. …”
Journal article