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8621
A Bayesian variable selection procedure to rank overlapping gene sets
Published 2012-05-01“…<p>Abstract</p> <p>Background</p> <p>Genome-wide expression profiling using microarrays or sequence-based technologies allows us to identify genes and genetic pathways whose expression patterns influence complex traits. …”
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Article -
8622
Functional immune-genomics of severe mental illness
Published 2023-04-01“…Results of screening of individuals with psychotic disorder using planar protein microarrays containing 42,100 human antigens representing 18,914 proteins will be presented. …”
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Article -
8623
RRM2 expression in different molecular subtypes of breast cancer and its prognostic significance
Published 2022-01-01“…Material and methods This study was performed by investigating RRM2 protein expression in breast cancer and correlating the results with other clinicopathological variables using immunohistochemistry and tissue microarrays. Results About 77% of cases were RRM2 positive. …”
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Article -
8624
Expression of Calretinin, Marker of Mesothelial Differentiation, in Pancreatic Ductal Adenocarcinoma: A Potential Diagnostic Pitfall
Published 2021-05-01“…Materials and Methods: Calretinin immunohistochemical staining was performed on the tissue microarrays (TMAs), which were created using three 0.6 mm diameter punches per tumor (n=113). …”
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Article -
8625
The HP0256 gene product is involved in motility and cell envelope architecture of <it>Helicobacter pylori</it>
Published 2010-04-01“…Interestingly, whole genome microarrays of an HP0256 mutant revealed transcriptional changes in a number of genes associated with the flagellar regulon and the cell envelope, such as outer membrane proteins and adhesins. …”
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Article -
8626
Classical, Molecular, and Genomic Cytogenetics of the Pig, a Clinical Perspective
Published 2021-04-01“…The next-generation of clinical cytogenetics include the implementation of DNA microarrays, and next-generation sequencing (NGS) technologies such as DNA sequencing to better explore tentative genome architecture changes. …”
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Article -
8627
Self-similar cuspidal formation by runaway thermocapillary forces in thin liquid films
Published 2019-01-01“…More practically, the system examined here introduces a potentially novel lithographic method for one-step non-contact fabrication of cuspidal microarrays.…”
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Article -
8628
Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue.
Published 2012-01-01“…These methods both enable rediscovery of RNA biomarkers for disease recurrence risk that were previously identified by RT-PCR analysis of a cohort of 136 patients, and also identify a high percentage of recurrence risk markers that were previously discovered using DNA microarrays in a separate cohort of patients, evidence that this RNA-Seq technology has sufficient precision and sensitivity for biomarker discovery. …”
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Article -
8629
Temporal transcriptomic response during arsenic stress in <it>Herminiimonas arsenicoxydans</it>
Published 2010-12-01“…</p> <p>Results</p> <p>Microarrays were designed to compare gene transcription profiles under a temporal As(III) exposure. …”
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Article -
8630
Toward functional profiling for eDNA‐based monitoring in coastal environments: A comparison of three approaches
Published 2024-01-01“…The methodologies included inference from 16S metabarcoding data using Tax4Fun, GeoChip microarrays, and shotgun metagenomics. Results revealed significant functional diversity across all sampling sites, irrespective of their environmental status. …”
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Article -
8631
Expression of Amine Oxidase Proteins in Adrenal Cortical Neoplasm and Pheochromocytoma
Published 2023-07-01“…We delved into the expression of amine oxidase family proteins and their potential significance in adrenal gland neoplasm. Tissue microarrays were prepared for 132 cases of adrenal cortical neoplasm (ACN) consisting of 115 cases of adrenal cortical adenoma (ACA), 17 cases of adrenal cortical carcinoma (ACC), and 163 cases of pheochromocytoma (PCC). …”
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Article -
8632
Getting everyone to agree on gene signatures for murine macrophage polarization in vitro.
Published 2024-01-01“…RNA sequencing (RNA-Seq) has revolutionized molecular biology, offering a comprehensive view of transcriptomes. Unlike microarrays, RNA-Seq detects known and novel transcripts, alternative splicing, and rare transcripts, providing a deeper understanding of genome complexity. …”
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Article -
8633
Multiplexed smFRET Nucleic Acid Sensing Using DNA Nanotweezers
Published 2023-01-01“…Although significant efforts have been made to develop more sensitive and rapid multiplexed screening methods, such as microarrays and electrochemical sensors, their limitations include their intricate sensing designs and semi-quantitative detection capabilities. …”
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Article -
8634
A genome-wide analysis reveals that the <it>Drosophila </it>transcription factor Lola promotes axon growth in part by suppressing expression of the actin nucleation factor Spire
Published 2011-11-01“…</p> <p>Results</p> <p>We use expression microarrays to identify the <it>lola</it>-dependent transcriptome in the <it>Drosophila </it>embryo. …”
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8635
Exploring the Roles of lncRNAs in GBM Pathophysiology and Their Therapeutic Potential
Published 2020-10-01“…The increased accessibility of next generation sequencing technologies and the advent of lncRNA-specific microarrays have facilitated the study of lncRNA etiology. …”
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Article -
8636
Quantification and signaling of alternatively spliced GFRα2 isoforms
Published 2003“…Transcriptional profiling with DNA microarrays demonstrated that the spliced isoforms do not share similar profiles. …”
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8637
Study of tumor-associated macrophages in triple-negative breast cancer and their correlation with clinicopathological parameters
Published 2014“…The expression levels of TAMs in both stromal (CD68S) and tumor nest (CD68T) regions were evaluated by performing immunohistochemistry using CD68 biomarker in tissue microarrays with tumors from 183 TNBC cancer cases. …”
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Final Year Project (FYP) -
8638
PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.
Published 2012“…METHODS: Immunohistochemical staining for PIM kinases and CXCR4 was performed on tissue microarrays from a cohort of 101 DLBCL cases, and the effects of PIM inhibitors on the survival and migration of DLBCL cell lines were determined. …”
Journal article -
8639
Isolation and characterization of human adipocyte-derived extracellular vesicles using filtration and ultracentrifugation
Published 2021“…Isolated EVs from this protocol can be used for downstream analysis, including transmission electron microscopy, proteomics, metabolomics, small RNA-sequencing, microarrays and can be utilized in functional in vitro/in vivo studies.…”
Journal article -
8640
Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor
Published 2005“…The CD200-COMP gave strong signals in protein microarrays, suggesting that such reagents may be valuable in high throughput detection of weak interactions. © 2005 Blackwell Publishing Ltd.…”
Journal article