Photoimmunotherapy targeting biliary‐pancreatic cancer with humanized anti‐TROP2 antibody by Takashi Nishimura, Makoto Mitsunaga, Ryoichi Sawada, Masayuki Saruta, Hisataka Kobayashi, Noriko Matsumoto, Toru Kanke, Hiroyuki Yanai, Koji Nakamura

“…Immunohistochemistry on PC and CC tissue microarrays confirmed that TROP2 is overexpressed in about half of PC and CC specimens. …”
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Fatty Acid Receptor CD36 Functions as a Surrogate Parameter for Lymph Node Metastasis in Oral Squamous Cell Carcinoma by Selgai Haidari, Matthias Tröltzsch, Thomas Knösel, Paris Liokatis, Anastasia Kasintsova, Marian Eberl, Florian Ortner, Sven Otto, Florian Fegg, Marko Boskov, Florian A. Probst

“…CD36 expression patterns were assessed by immunohistochemistry on tissue microarrays (TMA). Logistic regression analysis, survival analysis and Cox proportional hazards model were performed. …”
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Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide by Aleksandra Majchrzak-Celińska, Robert Kleszcz, Elżbieta Studzińska-Sroka, Agnieszka Łukaszyk, Anna Szoszkiewicz, Ewelina Stelcer, Karol Jopek, Marcin Rucinski, Judyta Cielecka-Piontek, Violetta Krajka-Kuźniak

“…Flow cytometry was applied to the analysis of oxidative stress, cell cycle distribution, and apoptosis, whereas qPCR and microarrays detected the induced transcriptomic changes. …”
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Molecular Biological Comparison of Dental Pulp- and Apical Papilla-Derived Stem Cells by Martyna Smeda, Kerstin M. Galler, Melanie Woelflick, Andreas Rosendahl, Christoph Moehle, Beate Lenhardt, Wolfgang Buchalla, Matthias Widbiller

“…Transcriptome-wide gene expression was profiled by microarrays and validated by quantitative reverse transcription PCR (qRT-PCR). …”
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GEO data mining identifies potential immune-related genes in hypertrophic scar and verities in a rabbit model by Hong Cai, Xuan Liu, Dingbin Liu, Bin Liu

“…Methods: We first screened out the potential immune-related genes in HTS microarrays via bioinformatics analysis using public datasets. …”
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Interferon-Alpha Decreases Cancer Stem Cell Properties and Modulates Exosomes in Malignant Melanoma by María Belén García-Ortega, Ernesto Aparicio, Carmen Griñán-Lisón, Gema Jiménez, Elena López-Ruiz, José Luis Palacios, Gloria Ruiz-Alcalá, Cristina Alba, Antonio Martínez, Houria Boulaiz, Macarena Perán, Michael Hackenberg, José Bragança, Sofia M. Calado, Juan A. Marchal, María Ángel García

“…Additionally, we investigated genomic modulations related to stemness properties using microRNA sequencing and microarrays. The effect of IFN-α on CSCs-derived exosomes was also analyzed using NanoSight and liquid chromatography (LC-HRMS)-based metabolomic analysis, among others. …”
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Experimental validation and bioinformatics analysis of hub genes in myocardial infarction by Li-Jun Wang, Bai-Quan Qiu, Hua-Xi Zou, Cheng-Wu Gong, Song-Qing Lai, Jian-Jun Xu, Yong-Bing Wu, Ji-Chun Liu

“…Dysregulated microRNAs (miRNAs) and messenger RNAs (mRNAs) based on two Gene Expression Omnibus microarrays were analyzed using bioinformatics technology and experiments. …”
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PD-L1 Testing and Squamous Cell Carcinoma of the Head and Neck: A Multicenter Study on the Diagnostic Reproducibility of Different Protocols by Simona Crosta, Renzo Boldorini, Francesca Bono, Virginia Brambilla, Emanuele Dainese, Nicola Fusco, Andrea Gianatti, Vincenzo L’Imperio, Patrizia Morbini, Fabio Pagni

“…The study applied 5 different protocols on 40 tissue microarrays from HNSCC. The error rate of the individual protocols ranged from a minimum of 7% to a maximum of 21%, the sensitivity from 79% to 96%, and the specificity from 50% to 100%. …”
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Expression Pattern of Leptin and Its Receptors in Endometrioid Endometrial Cancer by Dariusz Boroń, Robert Nowakowski, Beniamin Oskar Grabarek, Nikola Zmarzły, Marcin Opławski

“…The study material included tissue samples and whole blood collected from 30 patients with endometrial cancer and 30 without cancer. Microarrays were used to assess the expression profile of leptin-related genes. …”
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Oncobox Bioinformatical Platform for Selecting Potentially Effective Combinations of Target Cancer Drugs Using High-Throughput Gene Expression Data by Maxim Sorokin, Roman Kholodenko, Maria Suntsova, Galina Malakhova, Andrew Garazha, Irina Kholodenko, Elena Poddubskaya, Dmitriy Lantsov, Ivan Stilidi, Petr Arhiri, Andreyan Osipov, Anton Buzdin

“…We investigated gene expression profiles of intact and resistant cells by microarrays and analyzed alterations in 378 cancer-related signaling pathways using the bioinformatical platform Oncobox. …”
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Integument-Specific Transcriptional Regulation in the Mid-Stage of Flax Seed Development Influences the Release of Mucilage and the Seed Oil Content by Fabien Miart, Jean-Xavier Fontaine, Gaëlle Mongelard, Christopher Wattier, Michelle Lequart, Sophie Bouton, Roland Molinié, Nelly Dubrulle, Françoise Fournet, Hervé Demailly, Romain Roulard, Loïc Dupont, Arezki Boudaoud, Brigitte Thomasset, Laurent Gutierrez, Olivier Van Wuytswinkel, François Mesnard, Karine Pageau

“…Metabolite and transcript profiling (1H NMR and DNA oligo-microarrays) was performed on the seeds during seed development. …”
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S100A5 Attenuates Efficiency of Anti‐PD‐L1/PD‐1 Immunotherapy by Inhibiting CD8+ T Cell‐Mediated Anti‐Cancer Immunity in Bladder Carcinoma by Huihuang Li, Jinbo Chen, Zhenghao Li, Minfeng Chen, Zhenyu Ou, Miao Mo, Ruizhe Wang, Shiyu Tong, Peihua Liu, Zhiyong Cai, Chunyu Zhang, Zhi Liu, Dingshan Deng, Jinhui Liu, Chunliang Cheng, Jiao Hu, Xiongbing Zu

“…Clinically, there was a spatially exclusive relationship between S100A5+ tumor cells and CD8+ T cells in tissue microarrays. Moreover, S100A5 negatively correlated with immunotherapy efficacy in our real‐world and several public immunotherapy cohorts. …”
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A CD276-Targeted Antibody-Drug Conjugate to Treat Non-Small Lung Cancer (NSCLC) by Jiashuai Zhang, Zhuoxin (Zora) Zhou, Kai Chen, Seulhee Kim, Irene Soohyun Cho, Tanvi Varadkar, Hailey Baker, Ju Hwan Cho, Lufang Zhou, Xiaoguang (Margaret) Liu

“…Specifically, the CD276 receptor was evaluated and confirmed as an ideal surface target of NSCLC in the immunohistochemistry (IHC) staining of seventy-three patient tumor microarrays and western blotting analysis of eight cell lines. …”
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Influence of Tumor Stroma on the Aggressiveness of Poorly Cohesive Gastric Carcinoma by Giorgio Malpeli, Federica Filippini, Fabrizio Tedone, Lorena Torroni, Mariella Alloggio, Claudia Castelli, Mariagiulia Dal Cero, Roberto Perris, Anna Tomezzoli, Giovanni De Manzoni, Maria Bencivenga

“…We assessed the quantitative and qualitative impact of intralesional stroma on clinic-pathological features and the prognosis of poorly cohesive gastric cancer (PCGC) variants. Tissue microarrays including 75 PCGC specimens were immunostained for cytokeratin 8/18 and α-smooth muscle actin to assess the relative proportion of neoplastic cells versus stromal components and the cases were subsequently divided into stroma-rich (SR) and stroma-poor (SP) tumors. …”
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A Novel Artificially Humanized Anti-Cripto-1 Antibody Suppressing Cancer Cell Growth by Hiroko Ishii, Maram H. Zahra, Atushi Takayanagi, Masaharu Seno

“…The antibody was available to detect the immunoreactivity in tissue microarrays of malignant tumors as well as in Cripto-1 overexpressing cells. …”
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The Positive Correlations between the Expression of Histopathological Ubiquitin-Conjugating Enzyme 2O Staining and Prostate Cancer Advancement by Jae-Heon Kim, Hee-Jo Yang, Chang-Ho Lee, Youn-Soo Jeon, Jae-Joon Park, Kwang-Woo Lee, Jae-Ho Kim, Su-Yeon Park, Su-Jung Song, Yon-Hee Kim, Ah-Rim Moon, Ji-Hye Lee, Yun-Seob Song

“…Examination was also carried out into tissue microarrays (TMA) of human prostate cancer (<i>n</i> = 382) and adjacent non-neoplastic tissues around prostate cancer (<i>n</i> = 61). …”
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A Challenge for Allergologist: Application of Allergy Diagnostic Methods in Mast Cell Disorders by Jan Romantowski, Aleksandra Górska, Marek Niedoszytko, Theo Gulen, Marta Gruchała-Niedoszytko, Bogusław Nedoszytko, Magdalena Lange, Knut Brockow, Michel Arock, Cem Akin, Peter Valent

“…In the current article, we discuss the diagnosis and management of patients suffering from mastocytosis and concomitant MCAS, with special emphasis on novel diagnostic tests and management, including allergen microarrays, recombinant allergen analysis, basophil activation tests, optimal prophylaxis, and specific therapies.…”
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Tumoral Neuroligin 1 Promotes Cancer–Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor by Laura Bizzozero, Margherita Pergolizzi, Davide Pascal, Elena Maldi, Giulia Villari, Jessica Erriquez, Marco Volante, Guido Serini, Caterina Marchiò, Federico Bussolino, Marco Arese

“…Through immunohistochemistry on human tissue microarrays, we showed that NLGN1 is expressed by prostatic and pancreatic cancer tissues in discrete stages and tumor districts. …”
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DNA Methylation Analysis to Unravel Altered Genetic Pathways Underlying Early Onset and Late Onset Neonatal Sepsis. A Pilot Study by Sheila Lorente-Pozo, Sheila Lorente-Pozo, Paula Navarrete, María José Garzón, Inmaculada Lara-Cantón, Inmaculada Lara-Cantón, Jesús Beltrán-García, Jesús Beltrán-García, Rebeca Osca-Verdegal, Rebeca Osca-Verdegal, Salvador Mena-Mollá, Salvador Mena-Mollá, Eva García-López, Máximo Vento, Máximo Vento, Federico V. Pallardó, Federico V. Pallardó, Federico V. Pallardó, José Luis García-Giménez, José Luis García-Giménez, José Luis García-Giménez

“…The methylome analysis was performed in DNA from blood using Infinium Human Methylation EPIC microarrays to uncover methylation marks.Results: Methylation differential analysis revealed an alteration of methylation levels in genomic regions involved in inflammatory pathways which participate in both the innate and the adaptive immune response. …”
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Broad Environmental Tolerance for a <i>Salicola</i> Host-Phage Pair Isolated from the Cargill Solar Saltworks, Newark, CA, USA by Meghan L. Rodela, Shereen Sabet, Allison Peterson, Jesse G. Dillon

“…The host utilized 61 of 190 substrates tested using BIOLOG Phenotype MicroArrays. The CG&#966;29 phage, one of only four reported <i>Salicola</i> phages, is a DNA virus of the <i>Siphoviridae</i> family. …”
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