Upregulation of iNOS Protects Cyclic Mechanical Stretch-Induced Cell Death in Rat Aorta Smooth Muscle Cells by Jing Zhao, Kiichi Nakahira, Akihiko Kimura, Yoji Kyotani, Masanori Yoshizumi

“…The current study investigated the effects of inducible nitric oxide synthase (iNOS) on CMS-induced RASMC death. cDNA microarrays for CMS-treated RASMCs showed that iNOS expression levels were increased in response to CMS. …”
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Enhancement of Tumor Cell Immunogenicity and Antitumor Properties Derived from Platinum-Conjugated Iron Nanoparticles by Ángela-Patricia Hernández, Laura Iglesias-Anciones, José Javier Vaquero-González, Rafael Piñol, Julio J. Criado, Emilio Rodriguez, Pablo Juanes-Velasco, Marina L. García-Vaquero, Carlota Arias-Hidalgo, Alberto Orfao, Ángel Millán, Manuel Fuentes

“…Secondly, functional proteomics techniques based on microarrays have proven to be a successful method for high throughput screening of proteins and profiling of biomolecule mechanisms of action. …”
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Overexpression of RAB27A in Oral Squamous Cell Carcinoma Promotes Tumor Migration and Invasion via Modulation of EGFR Membrane Stability by Jue Huang, Jie-Gang Yang, Jian-Gang Ren, Hou-Fu Xia, Gao-Hong Chen, Qiu-Yun Fu, Lin-Zhou Zhang, Hai-Ming Liu, Kui-Ming Wang, Qi-Hui Xie, Gang Chen

“…The expression of RAB27A was assessed through immunohistochemical analysis utilizing tissue microarrays. In vitro experiments were conducted using RAB27A-knockdown cells to investigate its impact on OSCC tumor cells. …”
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The Platelet-Activating Factor Receptor’s Association with the Outcome of Ovarian Cancer Patients and Its Experimental Inhibition by Rupatadine by Eileen Deuster, Ivi Hysenaj, Maja Kahaly, Elisa Schmoeckel, Doris Mayr, Susanne Beyer, Thomas Kolben, Anna Hester, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla

“…In this study, we aimed to evaluate the prognostic value of PAFR in epithelial ovarian cancer (EOC) and the potential use of its antagonist, rupatadine, as an experimental treatment. Tissue microarrays of ovarian cancer patients, most markedly those with a non-mucinous subtype, immunohistochemically overexpressed PAFR. …”
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Analysis of LexA binding sites and transcriptomics in response to genotoxic stress in Leptospira interrogans by Schons-Fonseca, Luciane, da Silva, Josefa B., Milanez, Juliana S., Domingos, Renan H., Smith, Janet L., Nakaya, Helder I., Ho, Paulo L., da Costa, Renata MA, Grossman, Alan Davis

“…We determined the effects of DNA damage caused by ultraviolet radiation on gene expression in Leptospira interrogans using DNA microarrays. These data were integrated with DNA binding in vivo of LexA1, a regulator of the DNA damage response, assessed by chromatin immunoprecipitation and massively parallel DNA sequencing (ChIP-seq). …”
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Objective sequence-based subfamily classifications of mouse homeodomains reflect their in vitro DNA-binding preferences by Santos, Miguel A., Turinsky, Andrei L., Ong, Serene, Tsai, Jennifer, Berger, Michael F., Badis, Gwenael, Talukder, Shaheynoor, Gehrke, Andrew R., Hughes, Timothy R., Wodak, Shoshana J., Bulyk, Martha L.

“…Recently, in vitro DNA-binding preferences to all possible 8-nt DNA sequences have been measured for 178 mouse homeodomains using protein-binding microarrays, offering the unprecedented opportunity of evaluating the classification methods against quantitative measures of molecular function. …”
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Capillary-bridge controlled patterning of stable double-perovskite microwire arrays for non-toxic photodetectors by Pi, Yueyang, Zhao, Jinjin, Zhao, Yingjie, Feng, Jiangang, Zhang, Chi, Gao, Hanfei, Wu, Yuchen, Jiang, Lei

“…Our strategy provides a new perception to fabricate stable perovskite microarrays for the integration of non-toxic optoelectronic devices.…”
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Gene expression in human oral squamous cell carcinoma is influenced by risk factor exposure by Cheong, S.C., Chandramouli, G.V., Saleh, A., Zain, R.B., Lau, S.H., Sivakumaren, S., Pathmanathan, R., Prime, S.S., Teo, S.H., Patel, V., Gutkind, J.S.

“…In this study, we compared the gene expression patterns of oral cancers associated with BQ chewing to those caused by smoking using Affymetrix microarrays. We found that 281 genes were differentially expressed between OSCC and normal oral mucosa regardless of aetiological factors including MMP1, PLAU, MAGE-D4, GNA12, IFITM3 and NMU. …”
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Integrin-linked kinase expression in myeloid cells promotes colon tumorigenesis by Afsar U. Ahmed, Saleh Almasabi, Ron Firestein, Bryan R.G. Williams

“…In patient CRC tissue microarrays we observed elevated ILK+ myeloid (ILK+ CD11b+) cells in tumour sections compared to adjacent normal tissues, suggesting a conserved role for myeloid-ILK in CRC development in both human and animal models. …”
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Effects of aging and calorie restriction on the global gene expression profiles of mouse testis and ovary by Longo Dan L, Zonderman Alan B, Becker Kevin G, Poosala Suresh, Piao Yulan, Falco Geppino, Sharov Alexei A, Schlessinger David, Ko Minoru SH

“…As a first step to understand this phenomenon, we examine global changes in gene expression patterns by DNA microarrays in ovaries and testes of C57BL/6 mice at 1, 6, 16, and 24 months of age. …”
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REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker. by Laura Lehtinen, Pia Vesterkvist, Pia Roering, Taina Korpela, Liisa Hattara, Katja Kaipio, John-Patrick Mpindi, Johanna Hynninen, Annika Auranen, Ben Davidson, Caj Haglund, Kristiina Iljin, Seija Grenman, Harri Siitari, Olli Carpen

“…Candidate biomarker validation was done using qRT-PCR, western blotting and immunohistochemical staining of tumor tissue microarrays. The expression level of the candidate gene in serum was compared to the serum CA125 and HE4 levels in a patient cohort of prospectively collected advanced ovarian cancer. …”
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Gene expression in cortex and hippocampus during acute pneumococcal meningitis by Wittwer Matthias, Lindberg Raija LP, de Saizieu Antoine B, Voisin Veronique, Coimbra Roney S, Leppert David, Leib Stephen L

“…To analyze the biological significance of the data generated by Affymetrix DNA microarrays, a bioinformatics pipeline was used combining (i) a literature-profiling algorithm to cluster genes based on the vocabulary of abstracts indexed in MEDLINE (NCBI) and (ii) the self-organizing map (SOM), a clustering technique based on covariance in gene expression kinetics.…”
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Presence of activating <it>KRAS </it>mutations correlates significantly with expression of tumour suppressor genes <it>DCN </it>and <it>TPM1 </it>in colorectal cancer by Rems Miran, Štor Zdravko, Volavšek Metka, Berginc Gašper, Mlakar Vid, Glavač Damjan

“…</p> <p>Methods</p> <p>We used microarrays to identify novel genes involved in the development of CRC. …”
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Identification of proteins involved in neural progenitor cell targeting of gliomas by Honeth Gabriella, Zuchner Thole, Staflin Karin, Darabi Anna, Lundberg Cecilia

“…</p> <p>Methods</p> <p>Using microarrays we screened for candidate genes involved in the functional mechanism of tumor inhibition by comparing glioma cell lines to neural progenitor cells with or without anti-tumor activity. …”
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Comprehensive analysis of PRPF19 immune infiltrates, DNA methylation, senescence-associated secretory phenotype and ceRNA network in bladder cancer by YaXuan Wang, Jinfeng Wang, JiaXing He, Bo Ji, ZhongQi Pang, JianShe Wang, Yang Liu, MingHua Ren

“…However, the predictive value and biological function of PRPF19 in bladder urothelial carcinoma (BLCA) require further investigation.MethodsIn this study, we utilized transcriptomic data and bladder cancer tissue microarrays to identify the high expression of PRPF19 in BLCA, suggesting its potential as a prognostic biomarker. …”
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Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin by Sherman-Baust Cheryl A, Becker Kevin G, Wood III William H, Zhang Yongqing, Morin Patrice J

“…</p> <p>Methods</p> <p>To better understand mechanisms of drug resistance, and possibly identify novel targets for therapy, we generated a series of drug resistant ovarian cancer cell lines through repeated exposure to three chemotherapeutic drugs (cisplatin, doxorubicin, or paclitaxel), and identified changes in gene expression patterns using Illumina whole-genome expression microarrays. Validation of selected genes was performed by RT-PCR and immunoblotting. …”
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Profiling Antibiotic Resistance in <i>Acinetobacter calcoaceticus</i> by Janiece S. Glover, Taylor D. Ticer, Melinda A. Engevik

“…To profile the resistance patterns of <i>A. calcoaceticus</i>, strains were examined by Kirby–Bauer disk diffusion and phenotypic microarrays. We found that <i>Acinetobacter</i> strains were moderately to highly resistant to certain antibiotics within fluoroquinolones, aminoglycosides, tetracyclines, and other antibiotic classes. …”
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Fast rank-based normalization of miRNA qPCR arrays using support vector regression by Ali Mohammadian, Zahra Mortezaei, Yaser NejatyJahromy

“…Most normalization methods for continous expression data have been developed for mRNA microarrays and new and modified methods should be used for miRNA studies in general and RT-qPCR miRNA arrays in particular. …”
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Synaptic and genomic responses to JNK and AP-1 signaling in <it>Drosophila </it>neurons by Bohmann Dirk, Patel Chirag, Navratilova Zaneta, Narayanan Radhakrishnan, Etter Paul D, Jasper Heinrich, Ramaswami Mani

“…Here, we further investigated the role of JNK signaling at this model synapse employing an activated form of JNK-kinase; and using Serial Analysis of Gene Expression and oligonucleotide microarrays, searched for candidate early targets of JNK or AP-1 dependent transcription in neurons.…”
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Identification and differential expression of microRNAs during metamorphosis of the Japanese flounder (Paralichthys olivaceus). by Yuanshuai Fu, Zhiyi Shi, Minglin Wu, Junling Zhang, Liang Jia, Xiaowu Chen

“…We also demonstrated evolutionary conservation of Japanese flounder miRNAs and miRNA* in the animal evolution process. Using miRNA microarrays, we identified 66 differentially expressed miRNAs at two metamorphic stages (17 and 29 days post hatching) of Japanese flounder. …”
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