Novel <i>Antrodia cinnamomea</i> Extract Reduced Cancer Stem-Like Phenotype Changes and Resensitized <i>KRAS</i>-Mutant Colorectal Cancer via a MicroRNA-27a Pathway by Tsung-Jen Lin, Kuo-Chu Lai, An-Sheng Lee, Chien-Hsin Chang, Chiung-Lin Liu, Ching-Hu Chung

“…Using messenger RNA (mRNA) and microRNA (miRNA) microarrays, we found that <i>KRAS</i> gene expression was also regulated by AC009, possibly through specific miRNAs. …”
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Gene expression profiles and cytokine environments determine the in vitro proliferation and expansion capacities of human hematopoietic stem and progenitor cells by Roberto Dircio-Maldonado, Rosario Castro-Oropeza, Patricia Flores-Guzman, Alberto Cedro-Tanda, Fredy Omar Beltran-Anaya, Alfredo Hidalgo-Miranda, Hector Mayani

“…Their gene expression profiles were determined by RNA microarrays right after cell-sorting, before culture.Results HSCs showed the highest proliferation and expansion capacities in culture, and were found to be more closely related, in transcriptional terms, to MPCs than to EPCs. …”
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Immunohistochemical Glucagon-like Peptide-1 Receptor Expression in Human Insulinomas by Tiina Vesterinen, Elina Peltola, Helena Leijon, Päivi Hannula, Heini Huhtala, Markus J. Mäkinen, Lasse Nieminen, Elina Pirinen, Mikko Rönty, Mirva Söderström, Pia Jaatinen, Johanna Arola

“…After histological re-evaluation, formalin-fixed paraffin-embedded tissue samples were processed into tissue microarrays and stained immunohistochemically with a monoclonal GLP-1R antibody. …”
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Marginal zone lymphoma expression of histidine‐rich glycoprotein correlates with improved survival by Tor Persson Skare, Elin Sjöberg, Mattias Berglund, Ross O Smith, Francis P Roche, Cecilia Lindskog, Birgitta Sander, Ingrid Glimelius, Alex R Gholiha, Gunilla Enblad, Rose‐Marie Amini, Lena Claesson‐Welsh

“…Findings Immunohistochemical (IHC) analysis and RNA hybridization of tissue microarrays showed that (i) HRG was expressed by tumor cells in marginal zone lymphoma (MZL), in 36% of 59 cases. …”
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RFX6 facilitates aerobic glycolysis‐mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1 by Zhiyu Qiu, Chenwei Wang, Pinzhu Huang, Yichuan Yuan, Yunxing Shi, Zhu Lin, Zhenkun Huang, Dinglan Zuo, Jiliang Qiu, Wei He, Jingxian Shen, Yi Niu, Yunfei Yuan, Binkui Li

“…Although regulatory factor X6 (RFX6) is aberrantly expressed in different cancers, its precise role in cancer development remains ambiguous. Methods Microarrays of HCC tissues were employed to investigate the expression of RFX6 in tumour and adjacent non‐neoplastic tissues. …”
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The Calcium-Sensing Receptor is A Marker and Potential Driver of Neuroendocrine Differentiation in Prostate Cancer by Fanny Bery, Mathilde Cancel, Aurélie Chantôme, Roseline Guibon, Franck Bruyère, François Rozet, Karine Mahéo, Gaëlle Fromont

“…CaSR expression was evaluated by immunohistochemistry—together with NE markers—on tissue microarrays containing samples of normal prostate, localized PCa, metastatic castration resistant PCa (MCRPC) and NEPC. …”
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A Genome-Scale Metabolic Reconstruction of Phytophthora infestans With the Integration of Transcriptional Data Reveals the Key Metabolic Patterns Involved in the Interaction of Its... by David Botero, Iván Valdés, María-Juliana Rodríguez, Diana Henao, Giovanna Danies, Andrés F. González, Silvia Restrepo

“…Subsequently, transcriptional data (microarrays, RNA-seq) was integrated into the metabolic reconstruction to obtain context-specific (metabolic) models (CSMs) of the infection process, using constraint-based reconstruction and analysis. …”
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Analysis of Peripheral Blood Mononuclear Cells Gene Expression Highlights the Role of Extracellular Vesicles in the Immune Response following Hematopoietic Stem Cell Transplantatio... by Wojciech Strojny, Kinga Kwiecińska, Przemysław Hałubiec, Wojciech Kowalczyk, Karol Miklusiak, Agnieszka Łazarczyk, Szymon Skoczeń

“…Blood samples were obtained before HSCT and 6 months after the procedure. Microarrays were used to analyze gene expressions in peripheral blood mononuclear cells. …”
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Rapid Production and Genetic Stability of Human Mesenchymal Progenitor Cells Derived from Human Somatic Cell Nuclear Transfer-Derived Pluripotent Stem Cells by Soo Kyung Jung, Jeoung Eun Lee, Chang Woo Lee, Sung Han Shim, Dong Ryul Lee

“…Additionally, the analysis of gene expression patterns using microarrays showed very similar patterns. Moreover, array CGH analysis showed that both SCNT-PSC-Direct-MPCs and SCNT-PSC-EB-MPCs exhibited no significant differences in copy number variation (CNV) or single-nucleotide polymorphism (SNP) frequency. …”
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High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth by Marieke A. de Graaff, Shruti Malu, Irma Guardiola, Alwine B. Kruisselbrink, Yvonne de Jong, Willem E. Corver, H. Gelderblom, Patrick Hwu, Torsten O. Nielsen, Alexander J. Lazar, Neeta Somaiah, Judith V.M.G. Bovée

“…Cell lines and tissue microarrays were used for validation. As expected, all cell lines revealed a strong growth inhibition to conventional chemotherapeutic agents, such as anthracyclines and taxanes. …”
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ZNF768 Expression Associates with High Proliferative Clinicopathological Features in Lung Adenocarcinoma by Audrey Poirier, Andréanne Gagné, Philippe Laflamme, Meagan Marcoux, Michèle Orain, Sophie Plante, David Joubert, Philippe Joubert, Mathieu Laplante

“…Here, using tissue microarrays of clinical LUAD surgical specimens collected from 364 patients, we observed that high levels of ZNF768 is a common characteristic of LUAD. …”
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Identification of Cancer Stem Cell Molecular Markers and Effects of hsa-miR-21-3p on Stemness in Esophageal Squamous Cell Carcinoma by Zhikui Gao, Hui Liu, Yajuan Shi, Lihong Yin, Yong Zhu, Ran Liu

“…We further explored possible roles that microRNAs played in stem cells. Using microarrays, we identified that has-miR-21-3p was highly expressed in positive sorted cells, and further functional and Luciferase reporter assays verified that has-miR-21-3p promoted proliferation and anti-apoptosis by regulating TRAF4. …”
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Grapefruit Juice Flavanones Modulate the Expression of Genes Regulating Inflammation, Cell Interactions and Vascular Function in Peripheral Blood Mononuclear Cells of Postmenopausa... by Irena Krga, Karla Fabiola Corral-Jara, Nicolas Barber-Chamoux, Claude Dubray, Christine Morand, Dragan Milenkovic, Dragan Milenkovic

“…Modulated genes and microRNAs (miRNAs) were identified using microarrays. Bioinformatics analyses assessed their functions, interactions and correlations with previously observed changes in PWV. …”
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Comprehensive analysis of the gene expression profile of wheat at the crossroads of heat, drought and combined stress by Alsamman M. Alsamman, Ratiba Bousba, Michael Baum, Aladdin Hamwieh, Nourhan Fouad

“…We analyzed data from the Gene Expression Omnibus database (GEO) microarrays containing 24 samples of wheat, which were categorized by different treatments (control: ctrl, drought: D, heat: H, and mixed: HD). …”
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Synergistic Autophagy Effect of miR-212-3p in Zoledronic Acid-Treated In Vitro and Orthotopic In Vivo Models and in Patient-Derived Osteosarcoma Cells by Ju Yeon Oh, Eun Ho Kim, Yeon-Joo Lee, Sei Sai, Sun Ha Lim, Jang Woo Park, Hye Kyung Chung, Joon Kim, Guillaume Vares, Akihisa Takahashi, Youn Kyoung Jeong, Mi-Sook Kim, Chang-Bae Kong

“…ZOL induced autophagy by repressing the protein kinase B/mammalian target of rapamycin/p70S6 kinase pathway and extracellular signal-regulated kinase signaling-dependent autophagy in OS cell lines and patient-derived OS cells. Microarrays of miRNA showed that ZOL increased the levels of miR-212-3p, which is known to play an important role in autophagy, in OS in vitro and in vivo systems. …”
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Novel DNA methylation changes in mouse lungs associated with chronic smoking by Chinonye Doris Onuzulu, Samantha Lee, Sujata Basu, Jeannette Comte, Yan Hai, Nikho Hizon, Shivam Chadha, Maria Shenna Fauni, Andrew J. Halayko, Christopher D. Pascoe, Meaghan J. Jones

“…Finally, we carried out epigenome-wide DNAm analyses using the newly released Illumina mouse methylation microarrays. Our results recapitulate some of the phenotypes and DNAm patterns observed in human studies but reveal 32 differentially methylated genes specific to the lungs which have not been previously associated with smoking. …”
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Profiling Immune Escape in Hodgkin’s and Diffuse large B-Cell Lymphomas Using the Transcriptome and Immunostaining by Sarah Péricart, Marie Tosolini, Pauline Gravelle, Cédric Rossi, Alexandra Traverse-Glehen, Nadia Amara, Camille Franchet, Elodie Martin, Christine Bezombes, Guy Laurent, Pierre Brousset, Jean-Jacques Fournié, Camille Laurent

“…Thus, we explored the transcriptomic profiles of ~1000 HL and DLBCL using a comparative meta-analysis of their bulk microarrays. Relative to DLBCL, the HL co-clustered at the advanced stage of immune escape, displaying significant enrichment of both IE and T-cell activation genes. …”
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Uridine Inhibits Hepatocellular Carcinoma Cell Development by Inducing Ferroptosis by Liuliu Zi, Wangbin Ma, Lilong Zhang, Boyang Qiao, Zhendong Qiu, Junhui Xu, Jiacheng Zhang, Yahong Ye, Yueyuan Yang, Keshuai Dong, Chen Chen, Weixing Wang, Qingyan Zhao

“…In this study, the detection of genes associated with de novo uridine synthesis, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, dihydroorotase (CAD) (n = 115), and dihydroorotate dehydrogenase (DHODH) (n = 115) in HCC tissues through tissue microarrays revealed that the expression of CAD and DHODH was higher in tumor compared with paraneoplastic tissues. …”
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Hypoxia-responsive circular RNA circAAGAB reduces breast cancer malignancy by activating p38 MAPK and sponging miR-378 h by Kuan-Yi Lee, Chia-Ming Liu, Li-Han Chen, Chien-Yueh Lee, Tzu-Pin Lu, Li-Ling Chuang, Liang-Chuan Lai

“…Lastly, the functions of circAAGAB were explored by identifying its down-stream genes using Affymetrix microarrays and validated by in vitro assays. Results The results showed that circAAGAB reduced cell colony formation, cell migration, and signaling through p38 MAPK pathway, as well as increased radiosensitivity. …”
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Computational Strategies for the Identification of a Transcriptional Biomarker Panel to Sense Cellular Growth States in <i>Bacillus subtilis</i> by Yiming Huang, Wendy Smith, Colin Harwood, Anil Wipat, Jaume Bacardit

“…Patterns of gene expression, revealed using technologies such as microarrays or RNA-seq, can provide useful biomarkers of different gene regulatory states indicative of a bacterium’s physiological status. …”
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