Children, Adolescents, and Young Adults with Borderline Intellectual Functioning: Etiological, Neurophysiological, and Mri Findings in a Cohort of 651 Patients by Heli Sätilä, Laura Mirjami Jolma, Mikko Koivu-Jolma

“…The best etiologic yield leading to a diagnosis in this study population was with exome sequencing, a specific gene panel, microarrays, electroneuromyography, and brain magnetic resonance imaging (MRI). …”
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A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancer by Xin You, Lingling Huang, Ouxiang Huang, Yujie Deng, Xi Shi

“…The protein expression levels were validated in tissue microarrays, and the effects on tumor cell lines were accessed through MTS and colony formation assays. …”
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Tumor immune cell clustering and its association with survival in African American women with ovarian cancer. by Christopher Wilson, Alex C Soupir, Ram Thapa, Jordan Creed, Jonathan Nguyen, Carlos Moran Segura, Travis Gerke, Joellen M Schildkraut, Lauren C Peres, Brooke L Fridley

“…This approach was then applied to epithelial ovarian cancer (EOC) using mIF collected on intra-tumoral regions of interest (ROIs) and tissue microarrays (TMAs) from 160 high-grade serous ovarian carcinoma patients in the African American Cancer Epidemiology Study (AACES) (94 subjects on TMAs resulting in 263 tissue cores; 93 subjects with 260 ROIs; 27 subjects with both TMA and ROI data). …”
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Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells. by Cecilia Morell, Alicia Bort, Diana Vara-Ciruelos, Ágata Ramos-Torres, Manuel Altamirano-Dimas, Inés Díaz-Laviada, Nieves Rodríguez-Henche

“…Serum deprivation increased the expression of NE markers such as neuron-specific enolase (NSE) and βIII tubulin (βIII tub) and decreased the expression of the androgen receptor protein in LNCaP cells. Using cDNA microarrays, we compared gene expression profiles of NE cells and non-differentiated LNCaP cells. …”
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Spatiotemporal expression profiling of proteins in rat sciatic nerve regeneration using reverse phase protein arrays by Bryan David J, Litchfield C, Manchio Jeffrey V, Logvinenko Tanya, Holway Antonia H, Austin John, Summerhayes Ian C, Rieger-Christ Kimberly M

“…Reverse phase protein microarrays were used to identify the spatial and temporal expression profile of multiple proteins implicated in peripheral nerve regeneration including growth factors, extracellular matrix proteins, and proteins involved in adhesion and migration. …”
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The Mitochondrial Protein VDAC1 at the Crossroads of Cancer Cell Metabolism: The Epigenetic Link by Zohar Amsalem, Tasleem Arif, Anna Shteinfer-Kuzmine, Vered Chalifa-Caspi, Varda Shoshan-Barmatz

“…As the epigenome is sensitive to cellular metabolism, this study was designed to assess whether depleting VDAC1 affects the metabolism–epigenetics axis. Using DNA microarrays, q-PCR, and specific antibodies, we analyzed the effects of si-VDAC1 treatment of U-87MG-derived tumors on histone modifications and epigenetic-related enzyme expression levels, as well as the methylation and acetylation state, to uncover any alterations in epigenetic properties. …”
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Chemerin and Chemokine-like Receptor 1 Expression in Ovarian Cancer Associates with Proteins Involved in Estrogen Signaling by Florian Weber, Susanne Schueler-Toprak, Christa Buechler, Olaf Ortmann, Oliver Treeck

“…To further approach the role of this adipokine in ovarian cancer (OC), intratumoral protein levels of chemerin and its receptor chemokine-like receptor 1 (CMKLR1) were examined by immunohistochemistry analyzing tissue microarrays with tumor samples from 208 OC patients. …”
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MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma by Wang Rong, Liu Xiaoping, Xiao Lan, Lu Hongmei, Liu Wei, Zhang Baoxin, Wang Zeyou, Tang Hailin, Zhang Zuping, Li Xiaoling, Wu Minghua, Li Guiyuan

“…To determine how DNA methylation is modified in the genome of primary glioma, we used Methyl-DNA immunoprecipitation (MeDIP) and Nimblegen CpG promoter microarrays to identify differentially DNA methylation sequences between primary glioma and normal brain tissue samples.…”
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Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells by Santosh Kumar Singh, Manoj Kumar Mishra, Rajesh Singh

“…Hypoxia-induced genes are involved in metastasis-associated functions and in the epithelial-to-mesenchymal transition (EMT). Results Tissue microarrays of human OvCa showed elevated expression of CX3CR1 and HIF-1α compared to normal cells, and their levels were higher in adenocarcinoma stages II and III. …”
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Detection of condition-specific marker genes from RNA-seq data with MGFR by Khadija El Amrani, Gregorio Alanis-Lobato, Nancy Mah, Andreas Kurtz, Miguel A. Andrade-Navarro

“…We have previously developed MGFM, a tool for marker gene detection from microarrays, that is particularly useful in the latter case. …”
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Transcriptome Profiling of Peripheral Blood in 22q11.2 Deletion Syndrome Reveals Functional Pathways Related to Psychosis and Autism Spectrum Disorder. by Maria Jalbrzikowski, Maria T Lazaro, Fuying Gao, Alden Huang, Carolyn Chow, Daniel H Geschwind, Giovanni Coppola, Carrie E Bearden

“…Whole-genome transcriptional profiling was performed using Illumina Human HT-12 microarrays. Data mining techniques were used to validate our results against independent samples of both peripheral blood and brain tissue from idiopathic psychosis and ASD cases.Eighty-five percent of 22q11DS individuals (N = 39) carried the typical 3 Mb deletion, with significant variability in deletion characteristics in the remainder of the sample (N = 7). …”
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A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors. by Mai Isosaka, Takeshi Niinuma, Masanori Nojima, Masahiro Kai, Eiichiro Yamamoto, Reo Maruyama, Takayuki Nobuoka, Toshirou Nishida, Tatsuo Kanda, Takahiro Taguchi, Tadashi Hasegawa, Takashi Tokino, Koichi Hirata, Hiromu Suzuki, Yasuhisa Shinomura

“…The functions of miRNAs were examined using MTT assays, wound-healing assays, Boyden chamber assays and Matrigel invasion assays. Gene expression microarrays were analyzed to assess effect of ectopic miRNA expression in GIST-T1 cells.Of the 754 miRNAs analyzed, 61 were significantly upregulated in GIST-T1 cells treated with 5-aza-dC plus PBA. …”
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Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection. by Drew J Schwartz, Matt S Conover, Thomas J Hannan, Scott J Hultgren

“…Intracellular bacterial replication, regulated hemolysin (HlyA) expression, and caspase 1/11 activation were essential for this increase. Microarrays conducted at four weeks post inoculation in both mouse strains revealed upregulation of IL-1 and antimicrobial peptides during chronic cystitis. …”
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DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. by Kazuo Konishi, Yoshiyuki Watanabe, Lanlan Shen, Yi Guo, Ryan J Castoro, Kimie Kondo, Woonbok Chung, Saira Ahmed, Jaroslav Jelinek, Yanis A Boumber, Marcos R Estecio, Shinji Maegawa, Yutaka Kondo, Fumio Itoh, Michio Imawari, Stanley R Hamilton, Jean-Pierre J Issa

“…We also performed methylated CpG island amplification microarrays (MCAM) in three paired primary and metastatic cancers.Methylation of p14, TIMP3 and HPP1 in primary CRCs progressively decreased from absence to presence of liver metastasis (13.1% vs. 4.3%; 14.8% vs. 3.7%; 43.9% vs. 35.8%, respectively) (P<.05). …”
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386 The Analysis of N-glycans and Collagen to Predict Prostate Adenocarcinoma Outcome by Kaitlyn Bejar, Richard Drake, Peggi Angel, Teresa Johnson-Pais, Robin Leach

“…These approaches were used to analyze prostatectomy samples with different clinical outcomes. Tissue microarrays containing tissues from 75 non-progressors (no evidence of disease; NED) and 50 metastatic cases (MET) were examined. …”
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Transcriptomic and proteomic analysis of Oenococcus oeni adaptation to wine stress conditions by Mar Margalef-Català, Isabel Araque, Albert Bordons, Cristina Reguant, Joaquin Bautista-Gallego

“…In this study, the changes in the transcriptome and the proteome of O. oeni PSU-1 during the adaptation period before MLF start have been studied. DNA microarrays were used for the transcriptomic analysis and two complementary proteomic techniques, 2-D DIGE and iTRAQ labeling were used to analyze the proteomic response. …”
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MLH1 region polymorphisms show a significant association with CpG island shore methylation in a large cohort of healthy individuals. by Andrea J Savio, Mathieu Lemire, Miralem Mrkonjic, Steven Gallinger, Brent W Zanke, Thomas J Hudson, Bharati Bapat

“…To address whether MLH1 methylation in PBCs is correlated with tumorigenesis we utilized the Illumina 450 K microarrays to measure methylation in PBC DNA of 846 healthy controls and 252 CRC patients from Ontario, Canada. …”
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Characterization of genetic variants of vulnerability to epilepsy in Algerian families by Amina Chentouf, Mohand Laid Oubaiche, Malika Chaouch

“…After genomic DNA extraction, genetic variants of susceptibility to epilepsy were investigated by comparative genomic hybridization on DNA microarrays (CGH-array) and next-generation sequencing (NGS). …”
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Distinct Concentration-Dependent Molecular Pathways Regulate Bone Cell Responses to Cobalt and Chromium Exposure from Joint Replacement Prostheses by Karan M. Shah, Mark J. Dunning, Alison Gartland, J. Mark Wilkinson

“…In this study, we use whole-genome microarrays to comprehensively assess gene expression in primary human osteoblasts, osteoclast precursors and mature resorbing osteoclasts following exposure to clinically relevant circulating versus local periprosthetic tissue concentrations of Co²⁺ and Cr³⁺ ions and CoCr nanoparticles. …”
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Transferrin receptor in primary and metastatic breast cancer: Evaluation of expression and experimental modulation to improve molecular targeting. by Francesca Fontana, Alison K Esser, Christopher Egbulefu, Partha Karmakar, Xinming Su, John S Allen, Yalin Xu, Jennifer L Davis, Ariel Gabay, Jingyu Xiang, Kristin A Kwakwa, Brad Manion, Suzanne Bakewell, Shunqiang Li, Haeseong Park, Gregory M Lanza, Samuel Achilefu, Katherine N Weilbaecher

“…<h4>Methods</h4>Gene expression was investigated by datamining in twelve publicly-available datasets. Dedicated Tissue microarrays (TMAs) were generated to evaluate matched primary and bone metastases as well as and pre and post chemotherapy tumors from the same patient. …”
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