Analysis of the mechanism of propagated sensation along meridians based on gene expression profiles by Xiaoxiang Zhu, Jinsen Xu, Jian Wang, Zheyan Sa, Xiaohua Pan, Shuxia Zheng, Cailian Lan

“…Agilent Human 4 × 44 K Gene Expression Microarrays V2 were used to detect the whole genome expression profile of subjects in the two groups. …”
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Inhibition of SF3B1 improves the immune microenvironment through pyroptosis and synergizes with αPDL1 in ovarian cancer by Shourong Wang, Yao Liu, Huimin Xiao, Zhongshao Chen, Xiaohang Yang, Jingjing Yin, Yingwei Li, Cunzhong Yuan, Shi Yan, Gang Chen, Qinglei Gao, Beihua Kong, Chaoyang Sun, Kun Song

“…In this study, Clinical Proteomic Tumor Analysis Consortium (CPTAC) and The Cancer Genome Atlas (TCGA) cohorts were used to screen prognosis and cytotoxic lymphocyte infiltration-associated genes in upregulated genes of ovarian cancer, tissue microarrays were built for further verification. In vitro experiments and mouse (C57/BL6) ovarian tumor (ID8) models were built to evaluate the synergistic effect of the combination of SF3B1 inhibitor and PD-L1 antibody in the treatment of ovarian cancer. …”
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Clinical significance and immune infiltration analyses of a novel coagulation-related signature in ovarian cancer by Jiani Yang, Chao Wang, Yue Zhang, Shanshan Cheng, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu, Jindan Sheng, Dominic Chih-Cheng Voon, Yu Wang

“…Especially, based on tissue microarrays analysis, Quantitative real-time fluorescence PCR (qRT-PCR), and Western Blot, we found that aberrant upregulation of CRGs was related to poor prognosis in OV at both mRNA and protein level (p < 0.05). …”
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The role of LSM1 in breast cancer: Shaping metabolism and tumor-associated macrophage infiltration by Yen-Dun Tony Tzeng, Jui-Hu Hsiao, Pei-Yi Chu, Ling-Ming Tseng, Ming-Feng Hou, Yi-Ling Tsang, Ai-Ning Shao, Jim Jinn-Chyuan Sheu, Chia-Jung Li

“…These findings were confirmed using 54 BRCA patient biopsies and tissue microarrays. Immunofluorescence and bioinformatics assessed LSM1's connection to clinicopathological features and prognosis. …”
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Chlorpromazine affects glioblastoma bioenergetics by interfering with pyruvate kinase M2 by Claudia Abbruzzese, Silvia Matteoni, Paola Matarrese, Michele Signore, Barbara Ascione, Elisabetta Iessi, Aymone Gurtner, Andrea Sacconi, Lucia Ricci-Vitiani, Roberto Pallini, Andrea Pace, Veronica Villani, Andrea Polo, Susan Costantini, Alfredo Budillon, Gennaro Ciliberto, Marco G. Paggi

“…We performed a supervised recognition of the signal transduction pathways potentially influenced by CPZ via Reverse-Phase Protein microArrays (RPPA) and carried out an Activity-Based Protein Profiling (ABPP) followed by Mass Spectrometry (MS) analysis to possibly identify cellular factors targeted by the drug. …”
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PUMA and NOXA Expression in Tumor-Associated Benign Prostatic Epithelial Cells Are Predictive of Prostate Cancer Biochemical Recurrence by Sylvie Clairefond, Benjamin Péant, Véronique Ouellet, Véronique Barrès, Zhe Tian, Dominique Trudel, Pierre I. Karakiewicz, Anne-Marie Mes-Masson, Fred Saad

“…Methods: PUMA and NOXA expression levels were quantified on six tissue microarrays (TMAs) generated from radical prostatectomy samples (<i>n</i> = 285). …”
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Unraveling the Role of EV-Derived miR-150-5p in Prostate Cancer Metastasis and Its Association with High-Grade Gleason Scores: Implications for Diagnosis by Marian Cruz-Burgos, Sergio A. Cortés-Ramírez, Alberto Losada-García, Miguel Morales-Pacheco, Eduardo Martínez-Martínez, Jorge Gustavo Morales-Montor, Alejandro Servín-Haddad, J. Samuel Izquierdo-Luna, Griselda Rodríguez-Martínez, María del Pilar Ramos-Godínez, Vanessa González-Covarrubias, Abraham Cañavera-Constantino, Imelda González-Ramírez, Boyang Su, Hon S. Leong, Mauricio Rodríguez-Dorantes

“…This study aims to investigate the potential diagnostic utility of EV-derived microRNAs in liquid biopsies for prostate cancer. By employing microarrays on paraffin-embedded samples, we characterized the microRNA expression profiles in metastatic lymph nodes, non-metastatic lymph nodes, and primary tumor tissues of prostate cancer. …”
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Ductus Venosus Agenesis as a Marker of Pallister–Killian Syndrome by María Victoria Lapresa Alcalde, Ana María Cubo, María Carmen Martín Seisdedos, Javier Cortejoso Hernández, María José Doyague Sanchez, José María Sayagués

“…We also underscore the key role of new genetic techniques as microarrays to avoid misdiagnosis when only a subtle sonographic sign is present in complex conditions like this.…”
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The Protective Role of Decorin in Hepatic Metastasis of Colorectal Carcinoma by Andrea Reszegi, Zsolt Horváth, Katalin Karászi, Eszter Regős, Victoria Postniková, Péter Tátrai, András Kiss, Zsuzsa Schaff, Ilona Kovalszky, Kornélia Baghy

“…We also analyzed the effect of decorin in tissue microarrays of human colon carcinoma liver metastasis and examined whether the tumor cells can directly influence the decorin production of myofibroblasts. …”
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Combatting insects mediated biotic stress through plant associated endophytic entomopathogenic fungi in horticultural crops by Ipsita Samal, Tanmaya Kumar Bhoi, Prasanta Kumar Majhi, Sneha Murmu, Asit Kumar Pradhan, Dilip Kumar, Varun Saini, Amit Umesh Paschapur, M Nikhil Raj, Ankur, Suryakant Manik, Partha Pratim Behera, Deepak Kumar Mahanta, J. Komal, Pravej Alam, Thamer Al Balawi

“…NGS (Next Generation Sequencing), comparative genomics, proteomics, transcriptomics, metabolomics, metatranscriptomics and microarrays are used to evaluate plant-EEPF relationships. …”
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Estrogen Receptor-α Suppresses Liver Carcinogenesis and Establishes Sex-Specific Gene Expression by Mara H. O’Brien, Henry C. Pitot, Sang-Hyuk Chung, Paul F. Lambert, Norman R. Drinkwater, Andrea Bilger

“…Deficiency of <i>Esr2</i>, which encodes Estrogen Receptor-β, did not affect liver carcinogenesis in females. Using microarrays and QPCR to examine estrogen receptor effects on hepatic gene expression patterns, we found that germline <i>Esr1</i> deficiency resulted in the masculinization of gene expression in the female liver. …”
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Integrated analysis of circulating and tissue proteomes reveals that fibronectin 1 is a potential biomarker in papillary thyroid cancer by Guochao Ye, Xiaomei Zhang, Mansheng Li, Zixiang Lin, Yongcan Xu, Haoru Dong, Jie Zhou, Jiaqi Zhang, Sheng Wang, Yunping Zhu, Xiaobo Yu, Xu Qian

“…To address this concern, we performed an in-depth analysis of the serum proteomes of 26 PTC patients and 23 healthy controls using antibody microarrays and data-independent acquisition mass spectrometry (DIA-MS). …”
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Acute Effects of the Consumption of <i>Passiflora setacea</i> Juice on Metabolic Risk Factors and Gene Expression Profile in Humans by Isabella de Araújo Esteves Duarte, Dragan Milenkovic, Tatiana Karla dos Santos Borges, Artur Jordão de Magalhães Rosa, Christine Morand, Livia de Lacerda de Oliveira, Ana Maria Costa

“…Peripheral blood mononuclear cell (PBMC) from the same subjects were isolated and RNA was extracted for transcriptomic analyses using microarrays (study 2). Results: Insulin and homeostatic model assessment for insulin resistance (HOMA-IR) levels decreased statistically after the PS juice intake, whereas HDL level increased significantly. …”
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CD86+/CD206+, Diametrically Polarized Tumor-Associated Macrophages, Predict Hepatocellular Carcinoma Patient Prognosis by Pingping Dong, Lijie Ma, Longzi Liu, Guangxi Zhao, Si Zhang, Ling Dong, Ruyi Xue, She Chen

“…TAMs expression and density were assessed by immunohistochemical staining of CD68, CD86, and CD206 in tissue microarrays from 253 HCC patients. Clinicopathologic features and prognostic value of these markers were evaluated. …”
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LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma by Yuan Li, Shumei Song, Melissa Pool Pizzi, Guangchun Han, Ailing W. Scott, Jiankang Jin, Yan Xu, Ying Wang, Longfei Huo, Lang Ma, Christopher Vellano, Xiaolin Luo, Robert MacLeod, Linghua Wang, Zhenning Wang, Jaffer A. Ajani

“…RNA scope in situ hybridization was used to analyze PVT1 expression in tumor tissue microarrays (TMAs) of GAC and paired normal tissues from 792 patients. …”
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miR-1273h-5p suppresses CXCL12 expression and inhibits gastric cancer cell invasion and metastasis by Wang Yi-Chen, Lu Song, Zhou Xiao-Jiang, Yang Li, Liu Ping, Zhang Lan, Hu Yuan, Dong Xian-Zhe

“…The differential expression of microRNAs between GC and tumor-adjacent normal tissues was detected using microarrays, miR-1273h-5p, and chemokine (C-X-C motif) ligand 12 (CXCL12) mRNA, and protein levels were evaluated using polymerase chain reaction and Western blotting methods, cell proliferation, apoptosis, migration, and invasion were determined by CCK-8, flow cytometry, and transwell assay. …”
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CBP/β-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer by Alexander Ring, Cu Nguyen, Goar Smbatyan, Debu Tripathy, Min Yu, Michael Press, Michael Kahn, Julie E. Lang

“…In vitro and in vivo TNBC models were used to determine the therapeutic effect of CBP inhibition via ICG-001. Tissue microarrays (TMAs) were used to investigate the potential of CBP and associated proteins as biomarkers in TNBC. …”
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Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma by Lars M. Schiffmann, Heike Göbel, Heike Löser, Fabian Schorn, Jan Paul Werthenbach, Hans F. Fuchs, Patrick S. Plum, Marc Bludau, Thomas Zander, Wolfgang Schröder, Christiane J. Bruns, Hamid Kashkar, Alexander Quaas, Florian Gebauer

“…This study evaluated X-linked inhibitor of apoptosis protein (XIAP) as a potential marker improving outcome prediction. Methods Tissue microarrays from 362 patients that were diagnosed with resectable EAC were included in the study. …”
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SFMBT1 facilitates colon cancer cell metastasis and drug resistance combined with HMG20A by Ruijun Pan, Dingye Yu, Jiajia Hu, Xiao Yang, Chenxing Wang, Luyang Zhang, Pei Xue, Jing Sun, Xiaoping Zhang, Wei Cai

“…We detected the expression of SFMBT1 in CRC tissue microarrays by immunohistochemistry. The role of SFMBT1 in the migration, proliferation and invasion of CRC or resistance to 5-fluorouracil (5-FU) was determined using scratch assay, colony formation and Transwell assay. …”
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Whole stromal fibroblast signature is linked to specific chemokine and immune infiltration patterns and to improved survival in NSCLC by Stefan Koeck, Arno Amann, Johan Kern, Marit Zwierzina, Edith Lorenz, Sieghart Sopper, Heinz Zwierzina, Finn Mildner, Martina Sykora, Susanne Sprung, Hubert Hackl, Florian Augustin, Hubert T. Maier, Andreas Pircher, Georg Pall, Dominik Wolf, Gabriele Gamerith

“…Immune cell infiltration was assessed via flow cytometry, chemokines were analyzed by immunoassays and RNA microarrays. Results were confirmed in specimens from NSCLC patients by flow cytometry or immunohistochemistry as well as in the TCGA data set. …”
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