Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway by Zhong Hao, Xing Cong, Zhou Mi, Jia Zeyu, Liu Song, Zhu Shibo, Li Bo, Yang Hongjiang, Ma Hongpeng, Wang Liyue, Zhu Rusen, Qu Zhigang, Ning Guangzhi

“…Neuronal death and plasticity are detected by TUNEL staining and microelectrode array assays, respectively. mRNA sequencing and bioinformatics analysis are applied to predict the key targets of the action of ES on neurons, and the identified targets are validated by western blot analysis and qRT-PCR. …”
Get full text

Modulation of Theta-Band Local Field Potential Oscillations Across Brain Networks With Central Thalamic Deep Brain Stimulation to Enhance Spatial Working Memory by Ching-Wen Chang, Yu-Chun Lo, Sheng-Huang Lin, Sheng-Huang Lin, Shih-Hung Yang, Hui-Ching Lin, Ting-Chun Lin, Ssu-Ju Li, Christine Chin-jung Hsieh, Christine Chin-jung Hsieh, Vina Ro, Yueh-Jung Chung, Yun-Chi Chang, Chi-Wei Lee, Chi-Wei Lee, Chao-Hung Kuo, Chao-Hung Kuo, Chao-Hung Kuo, Shin-Yuan Chen, Shin-Yuan Chen, You-Yin Chen, You-Yin Chen, You-Yin Chen

“…Local field potentials (LFPs) were recorded from microelectrode array implanted in the CT, dentate gyrus, cornu ammonis (CA) region 1, and CA region 3. …”
Get full text

hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation by Yun Chang, Ya-nan Li, Rui Bai, Fujian Wu, Shuhong Ma, Amina Saleem, Siyao Zhang, Youxu Jiang, Tao Dong, Tianwei Guo, Chengwen Hang, Wen-jing Lu, Hongfeng Jiang, Feng Lan

“…Subsequently, high-throughput microelectrode array (MEA) assays and drug interventions were performed to characterise the electrophysiological signatures of hERG-deficient cell lines. …”
Get full text

Sensor signal conditioning circuit design for multi-electrode intra-cortical recording by Yi, Chen

“…Signal processing circuits can also be integrated with microelectrode array (MEA) to enable real-time on-chip processing and reduce the data transmission rate as well as the power consumption. …”
Get full text

Ascorbic acid can promote the generation and expansion of neuroepithelial-like stem cells derived from hiPS/ES cells under chemically defined conditions through promoting collagen... by Rui Bai, Yun Chang, Amina Saleem, Fujian Wu, Lei Tian, Siyao Zhang, Ya’nan Li, Shuhong Ma, Tao Dong, Tianwei Guo, Youxu Jiang, Yi You, Wen-Jing Lu, Hong Feng Jiang, Feng Lan

“…Subsequently, lt-NES cells were induced to neurons. A microelectrode array (MEA) recording system was used to evaluate the functionality of the neurons differentiated from lt-NES cells. …”
Get full text

Mass Transport to Nanoelectrode Arrays and Limitations of the Diffusion Domain Approach: Theory and Experiment by Godino, N, Borrise, X, Xavier Munoz, F, Javier del Campo, F, Compton, R

“…However, while microelectrode arrays tend to behave as macroelectrodes, nanoelectrode arrays on the other hand may behave as microelectrodes. …”

Investigating the concept of diffusional independence. Potential step transients at nano- and micro-electrode arrays: theory and experiment. by Menshykau, D, Huang, X, Rees, N, del Campo, F, Muñoz, F, Compton, R

“…Microelectrode arrays find broad application in electroanalysis offering the enhanced sensitivity associated with microelectrodes, but with a high total current output. …”

Modeling and Simulation of Enzymatic Biofuel Cells with Three-Dimensional Microelectrodes by Yin Song, Varun Penmatsa, Chunlei Wang

“…In this study, a computational model of EBFCs based on three-dimensional (3-D) interdigitated microelectrode arrays was conducted. The main focus of this research is to investigate the effect of different designs and spatial distributions of the microelectrode arrays on mass transport of fuels, enzymatic reaction rate, open circuit output potential and current density. …”
Get full text

Impedance Imaging of Cells and Tissues: Design and Applications by Raziyeh Bounik, Fernando Cardes, Hasan Ulusan, Mario M. Modena, Andreas Hierlemann

“…Advances in microfabrication and integrated-circuit technology have opened a route to using large-scale microelectrode arrays for real-time, high-spatiotemporal-resolution impedance measurements of biological samples. …”
Get full text

Electrochemical Properties of Sputtered Ruthenium Oxide Neural Stimulation and Recording Electrodes by Bitan Chakraborty

“…A chronically stable electrode material with a low impedance for recording neural activity, and a high charge-injection capacity for functional electro-stimulation is desirable for the fabrication of implantable microelectrode arrays that aim to restore impaired or lost neurological functions in humans. …”
Get full text

Distribution and Morphology of Calcium-Binding Proteins Immunoreactive Neurons following Chronic Tungsten Multielectrode Implants. by Marco Aurelio M Freire, Jean Faber, Nelson Alessandretti M Lemos, Jose Ronaldo Santos, Pedro França Cavalcanti, Ramon Hypolito Lima, Edgard Morya

“…Our results revealed that chronic microelectrode arrays were well tolerated by the nervous tissue, with recordings remaining viable for up to 6 months after implantation. …”
Get full text

A simultaneous optical and electrical in-vitro neuronal recording system to evaluate microelectrode performance. by Zaid Aqrawe, Nitish Patel, Yukti Vyas, Mahima Bansal, Johanna Montgomery, Jadranka Travas-Sejdic, Darren Svirskis

“…<h4>Objectives</h4>In this paper, we aim to detail the setup of a high spatio-temporal resolution, electrical recording system utilising planar microelectrode arrays with simultaneous optical imaging suitable for evaluating microelectrode performance with a proposed 'performance factor' metric.…”
Get full text

Eletrodos fabricados por "silk-screen" Screen-printed electrodes by Valberes B. Nascimento, Lúcio Angnes

“…Commercial and Home-made ink recipes are discussed. Microelectrode arrays, built by the combination of photostructuring and screen-printing technologies to the mass production of advanced disposable sensors, are also discussed. …”
Get full text

Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing by Siddharth Nimbalkar, Xiufang Guo, Alisha Colón, Max Jackson, Nesar Akanda, Aakash Patel, Marcella Grillo, James J. Hickman, James J. Hickman

“…These cells were also integrated with microelectrode arrays for analgesic drug testing to demonstrate their utilization in the preclinical drug screening process. …”
Get full text

Energy efficient neural stimulator with dynamic supply modulation by Aria Samiei, Hossein Hashemi

“…The functionality of the stimulator is verified in vitro using parylene‐based microelectrode arrays in phosphate‐buffered saline.…”
Get full text

Graphene oxide interfaces in serum based autoantibody quantification. by Xu, Q, Cheng, H, Lehr, J, Patil, A, Davis, J

“…We report herein the use of cysteamine-graphene oxide modified gold microelectrode arrays in underpinning the ultrasensitive and entirely label free non-faradaic quantification of Parkinson's-relevant autoantibodies in human serum.…”

Developments and Applications of Electrogenerated Chemiluminescence Sensors Based on Micro- and Nanomaterials by David T. Pierce, Julia Xiaojun Zhao, Xingwang Zheng, Sandra G. Hazelton

“…Sensor configurations including microelectrode arrays and microfluidics are reviewed and, with the recent trend toward increased use of nanomaterials, special attention has been given to sensors which include thin films, nanoparticles and nanotubes. …”
Get full text

Extracellular detection of neuronal coupling by Elmer Guzman, Zhuowei Cheng, Paul K. Hansma, Kenneth R. Tovar, Linda R. Petzold, Kenneth S. Kosik

“…Our method uses microelectrode arrays on which neurons are cultured and from which propagation of extracellular action potentials (eAPs) in single axons are recorded at multiple electrodes. …”
Get full text

Stripping analysis using boron-doped diamond electrodes by Jones, S, Compton, R

“…This review covers work on a wide range of analytical applications and enhancement techniques for stripping voltammetry at boron-doped diamond electrodes including the use of power ultrasound, microwave radiation, lasers and microelectrode arrays. © 2008 Bentham Science Publishers Ltd.…”

Voltammetry at spatially heterogeneous electrodes by Davies, T, Banks, C, Compton, R

“…In this way the electrochemical response of partially blocked electrodes and microelectrode arrays may be predicted, and are found to be consistent with experimental data. …”