Total ginsenosides suppress monocrotaline-induced pulmonary hypertension in rats: involvement of nitric oxide and mitogen-activated protein kinase pathways by Na Qin, Wei Yang, Dongxu Feng, Xinwen Wang, Muyao Qi, Tianxin Du, Hongzhi Sun, Shufang Wu

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Bmp4 in Zebrafish Enhances Antiviral Innate Immunity through p38 MAPK (Mitogen-Activated Protein Kinases) Pathway by Lihui Chen, Shenjie Zhong, Yajun Wang, Xinyuan Wang, Zhenhui Liu, Guobin Hu

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Epidermal growth factor-mediated mitogen-activated protein kinase3/1 pathway is conducive to in vitro maturation of sheep oocytes. by Hemin Ni, Xihui Sheng, Xu Cui, Meichao Gu, Yunhai Liu, Xiaolong Qi, Shuhan Xing, Yong Guo

“…In the present study, we investigated the effect of EGF-mediated mitogen-activated protein kinases 3 and 1 (MAPK3/1) pathway on in vitro maturation of sheep oocytes. …”
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Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling by Angelini Daniel J, Su Qingning, Yamaji-Kegan Kazuyo, Fan Chunling, Skinner John T, Poloczek Andre, El-Haddad Hazim, Cheadle Chris, Johns Roger A

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Chemerin Stimulates Vascular Smooth Muscle Cell Proliferation and Carotid Neointimal Hyperplasia by Activating Mitogen-Activated Protein Kinase Signaling. by Wei Xiong, Yu Luo, Lin Wu, Feng Liu, Huadong Liu, Jianghua Li, Bihong Liao, Shaohong Dong

“…Additionally, inhibition of chemerin down-regulated the expression of several proteins, including phosphorylated p38 mitogen-activated protein kinase, phosphorylated extracellular signal regulated kinase 1/2, nuclear factor-kappa B p65, and proliferation cell nuclear antigen. …”
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Integration of In Silico Strategies for Drug Repositioning towards P38α Mitogen-Activated Protein Kinase (MAPK) at the Allosteric Site by Utid Suriya, Panupong Mahalapbutr, Thanyada Rungrotmongkol

“…P38α mitogen-activated protein kinase (p38α MAPK), one of the p38 MAPK isoforms participating in a signaling cascade, has been identified for its pivotal role in the regulation of physiological processes such as cell proliferation, differentiation, survival, and death. …”
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Effects of estrogens and bladder inflammation on mitogen-activated protein kinases in lumbosacral dorsal root ganglia from adult female rats by Keast Janet R, Cheng Ying

“…The aim of this study was to determine if estrogens could directly modulate signalling pathways within bladder sensory neurons, such as extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases. These signalling pathways have been implicated in neuronal plasticity underlying development of inflammatory somatic pain but have not been as extensively investigated in visceral nociceptors. …”
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In vitro effect of copper treatments on mitogenic response and superoxide dismutase expression of lead exposed leukocytes from periparturient dairy cows by MUNEENDRA KUMAR, HARJIT KAUR, BHUPENDRA TULSIDAS PHONDBA, VEENA MANI, NEELAM GUPTA, AMRISH KUMAR TYAGI, RAJU KUSHWAHA, GULAB CHANDRA

“…Reduced mitogenic response of lymphocytes and mRNA expression of SOD was reported in Pb-treated groups as compared to control. …”
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Periodic Mechanical Stress Stimulates GIT1-Dependent Mitogenic Signals in Rat Chondrocytes Through ERK1/2 Activity by Kewei Ren, Jilei Tang, Xuefeng Jiang, Huiqing Sun, Luming Nong, Nan Shen, Yanqing Gu

“…Background/Aims: The mitogenic effects of periodic mechanical stress on chondrocytes have been studied extensively, but the mechanisms whereby chondrocytes sense and respond to mechanical stimuli remain to be determined. …”
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The CsSTE50 Adaptor Protein in Mitogen-Activated Protein Kinase Cascades Is Essential for Pepper Anthracnose Disease of Colletotrichum scovillei by Jong-Hwan Shin, Byung-Seong Park, Kyoung Su Kim

“…Several signaling cascades, including cAMP-mediated signaling and mitogen-activated protein kinase (MAPK) cascades, are involved in fungal development and pathogenicity in plant pathogenic fungi, but this has not been well studied in the fruit-infecting fungus C. scovillei. …”
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Alkannin reverses lipopolysaccharides-induced inflammatory responses by suppressing mitogen-activated protein kinase and nuclear factor kappa-B signalling by Jingya Yang, Jing Li, Lanzhu Yang, Ruohui Guo

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The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis. by Ralf Müller, Christoph Daniel, Christian Hugo, Kerstin Amann, Dirk Mielenz, Karlhans Endlich, Tobias Braun, Betty van der Veen, Peter Heeringa, Georg Schett, Jochen Zwerina

“…p38 mitogen-activated protein kinase (MAPK) is thought to play a central role in acute and chronic inflammatory responses. …”
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Biochemical and Genetic Interactions of Phospholipase D Alpha 1 and Mitogen-Activated Protein Kinase 3 Affect Arabidopsis Stress Response by Pavol Vadovič, Olga Šamajová, Tomáš Takáč, Dominik Novák, Veronika Zapletalová, Jean Colcombet, Jozef Šamaj

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Big Mitogen-Activated Protein Kinase 1 Protects Cultured Rat Aortic Smooth Muscle Cells From Oxidative Damage by Jing Zhao, Yoji Kyotani, Satoyasu Itoh, Hitoshi Nakayama, Minoru Isosaki, Masanori Yoshizumi

“…In vascular smooth muscle cells, oxidative stress–induced cell death (including apoptosis) is probably related to arterial calcification in arteriosclerosis. Big mitogen-activated protein kinase-1 / extracellular signal–regulated kinase 5 (BMK1/ERK5) is a newly identified member of the mitogen-activated protein kinases family. …”
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TRAF6 promotes myogenic differentiation via the TAK1/p38 mitogen-activated protein kinase and Akt pathways. by Fang Xiao, Haixia Wang, Xinrong Fu, Yanfeng Li, Zhenguo Wu

“…p38 mitogen-activated protein kinase (MAPK) is an essential kinase involved in myogenic differentiation. …”
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Molecular characterization and immunohistochemical localization of a mitogen-activated protein kinase, Accp38b, from Apis cerana cerana by Liang Zhang, Fei Meng, Yuzhen Li, Mingjiang Kang, Xingqi Guo, Baohua Xu

“…The p38 mitogen-activated protein kinase (MAPK) is involvedin various processes, including stress responses, development,and differentiation. …”
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Mannitol inhibits the proliferation of neural stem cell by a p38 mitogen-activated protein kinase-dependent signaling pathway by Hai-Zhen Duan, Xin Zhou, Quan Hu, Meng-Long Liu, Shu-Hong Wang, Ji Zhang, Xu-Heng Jiang, Tian-Xi Zhang, An-Yong Yu

“…Finally, to further confirm the involvement of the p38 mitogen-activated protein kinase-dependent (MAPK) signaling pathway in the observed inhibition of NSC proliferation by mannitol, SB203580 was employed. …”
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Dual p38/JNK mitogen activated protein kinase inhibitors prevent ozone-induced airway hyperreactivity in guinea pigs. by Kirsten C Verhein, Francesco G Salituro, Mark W Ledeboer, Allison D Fryer, David B Jacoby

“…Ozone reacts with the epithelial lining fluid and airway epithelium to produce reactive oxygen species and lipid peroxidation products, which then activate cell signaling pathways, including the mitogen activated protein kinase (MAPK) pathway. Both p38 and c-Jun NH2 terminal kinase (JNK) are MAPK family members that are activated by cellular stress and inflammation. …”
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Expression and localization of estrogen receptor-β in annulus cells of the human intervertebral disc and the mitogenic effect of 17-β-estradiol in vitro by Leslie Kelly, Ingram Jane, Yamaguchi Dean, Gruber Helen E, Huang Weibiao, Miller Timothy A, Hanley Edward N

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The Expression of Connexin 26 Regulates the Radiosensitivity of Hepatocellular Carcinoma Cells through a Mitogen-Activated Protein Kinases Signal Pathway by Yuan Li, Li Yang, Rui Tao, Yajing Shang, Minqiong Sun, Shichao Peng, Guoping Zhao, Ye Zhao

“…The cell survival, micronucleus formation and protein expressions of the mitogen-activated protein kinases (MAPK) signaling pathway were detected. …”
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