Bioprosthesis in the Mitral Position: Bovine Pericardial versus Porcine Xenograft by Dong Youb Han, Sung Jun Park, Ho Jin Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee, Joon Bum Kim

“…Those with prior MVR, infective endocarditis, congenital mitral valve disease, or ischemic mitral regurgitation were excluded. …”

Comparison of Perioperative and Postoperative Outcomes Among 3 Left Atrial Incisions: Conventional Direct, Transseptal, and Superior Septal Left Atriotomy by Estelle Démoulin, Dionysios Adamopoulos, MD, Tornike Sologashvili, MD, Mathieu van Steenberghe, MD, PhD, Jalal Jolou, MD, Haran Burri, MD, PhD, Christoph Huber, MD, PhD, Mustafa Cikirikcioglu, MD, PhD

“…Results No substantial variance was observed in the etiology of mitral valve disease across groups, except for a higher incidence of endocarditis in group 3 (P = .01). …”
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Mitral Valve Surgery by Right Minithoracotomy Vs Traditional Median Full Sternotomy by Muhammad Aamir Khan, Tahseen Ahmed, Nausheen Shaukat, Asif Mahmood Janjua, Muhammad Afsheen Iqbal, Syed Muzaffir Hasan Kirmani, Rehana Javaid

“…Methodology: From December 2013 to March 2020, 721 patients with various mitral valve diseases were treated at our institute with isolated mitral valve surgery. 50 patients had (MIMVS). 670 patients, on the other hand, underwent conventional median full sternotomy (MFS) mitral valve surgery. …”
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Proposta de escore de risco para predição de fibrilação atrial após cirurgia cardíaca Risk index proposal to predict atrial fibrillation after cardiac surgery by Rogério Gomes da Silva, Gustavo Glotz de Lima, Nelma Guerra, André Vicente Bigolin, Lucas Celia Petersen

“…The most associated factors with AF were: patients older than 75 years of age, mitral valve disease, no use of a beta blocker, withdrawal of a beta-blocker and a positive fluid balance. …”
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Profiling Genome-Wide DNA Methylation Patterns in Human Aortic and Mitral Valves by Sarah Halawa, Sarah Halawa, Najma Latif, Najma Latif, Yuan-Tsan Tseng, Yuan-Tsan Tseng, Ayman M. Ibrahim, Ayman M. Ibrahim, Adrian H. Chester, Adrian H. Chester, Ahmed Moustafa, Ahmed Moustafa, Yasmine Aguib, Yasmine Aguib, Magdi H. Yacoub, Magdi H. Yacoub, Magdi H. Yacoub

“…Analysis of methylation data [reduced representation bisulfite sequencing (RRBS)] of 16,101 promoters genome-wide revealed 584 differentially methylated (DM) promoters, of which 13 were reported in endothelial mesenchymal trans-differentiation (EMT), 37 in aortic and mitral valve disease and 7 in ECM remodeling. Both functional classification as well as network analysis showed that the genes associated with the DM promoters were enriched for WNT-, Cadherin-, Endothelin-, PDGF-, HIF-1 and VEGF- signaling implicated in valvular physiology and pathophysiology. …”
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Automated mitral valve assessment for transcatheter mitral valve replacement planning by Patricia Lopes, Patricia Lopes, Patricia Lopes, Paul L. Van Herck, Joris F. Ooms, Nicolas M. Van Mieghem, Roel Wirix-Speetjens, Jan Sijbers, Jos Vander Sloten, Johan Bosmans

“…Transcatheter mitral valve replacement (TMVR) has emerged as a minimally invasive alternative for treating patients suffering from mitral valve disease. The number of TMVR procedures is expected to rise as devices currently in clinical trials obtain approval for commercialization. …”
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Transferring Surgical Expertise: Analyzing the Learning Curve of Robotic Cardiac Surgery Operative Time Reduction When Surgeon Moves from One Experienced Center to Another by Sherif M. Khairallah, Mohamed Rahouma, Stephanie L. Mick

“…The median patient age was 63 years, 68% were males, 90.3% of cases were repaired for degenerative mitral valve disease, and the median body mass index was 23.87. …”
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Left Atrial Reduction Plasty and Sinus Rhythm Restoration in patients undergoing Mitral Valve Surgery with Chronic Atrial Fibrillation by Nasir Ali, Atif Nawaz, Imtiaz Ahmed Chaudhry, Muhammad Imran Asghar, Syed Aqeel Hussain, Rehan Masroor, Muhammad Ahmad Khan

“…Methodology: Thirty three (n=33) patients with mitral valve disease were recruited via convenience sampling, all of whom exhibited an enlarged left atrium and pre-operative Atrial Fibrillation (AF). …”
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Impact of Surgical Ablation of Atrial Fibrillation on the Progression of Tricuspid Regurgitation and Right‐Sided Heart Remodeling After Mitral‐Valve Surgery: A Propensity‐Score Mat... by Jiangang Wang, Jie Han, Yan Li, Qing Ye, Fei Meng, Tiange Luo, Baiyu Tian, Haibo Zhang, Yixin Jia, Wen Zeng, Chunlei Xu, Wei Han, Yuqing Jiao, Xu Meng

“…ConclusionsIn a retrospective PSM analysis, mitral valve disease with AF was associated with TR progression as well as right‐sided heart remodeling, which are alleviated by surgical ablation.…”
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Association of echocardiographic measures of left ventricular diastolic dysfunction and hypertrophy with presence of coronary microvascular dysfunction by Iryna Dykun, Luisa Kärner, Ihab Mahmoud, Stefanie Hendricks, Matthias Totzeck, Fadi Al-Rashid, Tienush Rassaf, Amir A. Mahabadi

“…Methods: We retrospectively included patients undergoing diagnostic coronary angiography and transthoracic echocardiography, excluding patients with obstructive coronary artery disease, previous revascularization therapy, moderate or severe mitral valve disease, or atrial fibrillation. The following markers of LV diastolic function and hypertrophy were assessed: E- and A-wave velocity, E-wave deceleration time, E/A- and E/E′-ratio, left atrial area, left LV mass index, LV ejection time (LVET) and mitral valve closure to opening time. …”
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Incremental Prognosis by Left Atrial Functional Assessment: The Left Atrial Coupling Index in Patients With Floppy Mitral Valves by Benjamin Essayagh, Giovanni Benfari, Clémence Antoine, Joseph Maalouf, Sorin Pislaru, Prabin Thapa, Hector I. Michelena, Maurice Enriquez‐Sarano

“…Higher LACI is associated with worse clinical presentation, but irrespective of baseline characteristics, LACI is strongly, independently, and incrementally determinant of outcome, demonstrating the crucial importance of LA functional response to mitral valve disease.…”
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Clinical Outcome of Rheumatic Mitral Valve Repair and Replacement Surgery in Indonesia; A Comparison with Non-Rheumatic Aetiology by Amiliana Mardiani Soesanto, Estu Rudiktyo, Amin Tjubandi, Rina Ariani, Fadhila Nafilah Azzahra, Mochammad Faisal Adam, Ario Soeryo Kuncoro

“…However, that cannot be applied in rheumatic mitral valve disease. Therefore, this study aims to evaluate early and late clinical outcomes and mid-term survival in RHD compared to the non-RHD group and whether mitral valve repair is a better surgical approach in RHD patients. …”
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Minithoracotomy versus sternotomy in mitral valve surgery: meta-analysis from recent matched and randomized studies by Adel Al Shamry, Margaux Jegaden, Salah Ashafy, Armand Eker, Olivier Jegaden

“…Conclusions The present meta-analysis confirms that the MTH approach for mitral valve disease remains associated with prolonged operative times, but it is beneficial in terms of reduced postoperative complications (renal failure, atrial fibrillation, blood transfusion, wound infection), length of stay in ICU and in hospitalization, with finally a reduction in global cost. …”
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Urgent transcatheter edge-to-edge repair for severe mitral regurgitation with flail leaflet in critically Ill patients by Nimrod Perel, Itshak Amsalem, Or Gilad, Rafael Hitter, Tomer Maller, Elad Asher, Emanuel Harari, David Marmor, Shemy Carasso, Shemy Carasso, Danny Dvir, Michael Glikson, Mony Shuvy

“…IntroductionDegenerative mitral valve disease (DMR) is a common valvular disorder, with flail leaflets due to ruptured chordae representing an extreme variation of this pathology. …”
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A multicenter, retrospective study of cardiac disease in Borzoi dogs by K. Tess Sykes, Sonya Wesselowski, Ashley B. Saunders, Sonja S. Tjostheim, Brianna M. Potter, Anna R. M. Gelzer, Natalie Katz, Jessica L. Ward, Emily T. Karlin, Lauren E. Markovic, Aliya N. Magee, Jonathan A. Abbott, Saki Kadotani, Giulio Menciotti

“…Tricuspid valve dysplasia was the most commonly diagnosed congenital cardiac disease (n = 6). Myxomatous mitral valve disease (n = 12) and dilated cardiomyopathy (n = 13) were diagnosed at similar frequencies, though 92% of valve disease cases were mild. …”
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Variable clinical expression of a Belgian TGFB3 founder variant suggests the presence of a genetic modifier by Melanie H. A. M. Perik, Emmanuela Govaerts, Steven Laga, Inge Goovaerts, Inge Goovaerts, Johan Saenen, Emeline Van Craenenbroeck, Josephina A. N. Meester, Ilse Luyckx, Ilse Luyckx, Inez Rodrigus, Aline Verstraeten, Lut Van Laer, Bart L. Loeys, Bart L. Loeys

“…Variable clinical features included connective tissue manifestations, non-aneurysmal cardiovascular problems such as hypertrophic cardiomyopathy, bicuspid aortic valve, mitral valve disease, and septal defects. Remarkably, only in 4 out of the 27 variant-harboring individuals, significant aortic involvement was observed. …”
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Comparative study of percutaneous transvenous mitral commissurotomy using ACCURA balloon in juvenile vs adult rheumatic mitral stenosis by Sunil Kumar Kondethimmanahally Rangaiah, Amulya Cherukumudi, Parvat Kumar Dash, Banajit Barooah

“…Conclusion: Juvenile patients had severe mitral valve disease with severe pulmonary arterial hypertension at presentation, both echocardiographically and hemodynamically than adult patients. …”
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Cirurgia cardíaca videoassistida: 6 anos de experiência Video-assisted cardiac surgery: 6 years of experience by Jeronimo Antonio Fortunato Júnior, Marcelo Luiz Pereira, André Luiz M. Martins, Daniele de Souza C. Pereira, Maria Evangelista Paz, Luciana Paludo, Alcides Branco Filho, Branka Milosewich

“…METHODS: 136 patients underwent VACS, after written consent, between September 2005 and October 2011, 50% for men and age of 47.8 ± 15, 4anos, divided into two groups: with cardiopulmonary (CEC) (GcCEC=105 patients): mitral valve disease (47/105), aortic disease (39/105), congenital heart disease (19/105) and without extracorporeal circulation (CEC) (GsCEC=31 patients): cardiac resynchronization (18/ 31), cardiac tumor (4/31) and minimally invasive coronary artery bypass grafting (6/31). …”
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Comparison between radial artery tonometry pulse analyzer and pulsed-Doppler echocardiography derived hemodynamic parameters in cardiac surgery patients: a pilot study by Rashad Zayat, Andreas Goetzenich, Ju-Yeon Lee, HeeJung Kang, So-Hyun Jansen-Park, Thomas Schmitz-Rode, Giulia Musetti, Heike Schnoering, Rüdiger Autschbach, Nima Hatam, Ali Aljalloud

“…Exclusion criteria were, inter alia, moderate to severe aortic- or Mitral valve disease and peripheral arterial disease (PAD) > stage II. …”
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Nova abordagem técnica para papilopexia cruzada em operação de substituição valvar mitral: resultados imediatos New technical approach for crossed papillopexy in mitral valve repla... by Otoni Moreira Gomes, Eros Silva Gomes, Geraldo Paulino Santana Filho, José Carlos Dorsa Vieira Pontes, Ricardo Adala Benfatti

“…METHOD: Ten patients, 70% male, with ages between 15 and 75 years old (mean 44.4 ± 18.7 years old), suffering from rheumatic mitral valve disease (50%), mitral valve prolapse (10%) or dilated cardiomyopathy (40%), were studied. …”
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