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    Non-fluorescent schemes for single-molecule detection, imaging and spectroscopy by Arroyo, J, Kukura, P

    Published 2015
    “…The availability of alternative approaches for single-molecule interrogation would greatly expand the range of addressable molecules beyond species that are highly emissive and photostable, thus offering new applications in fields other than molecular biophysics and imaging. Here, we discuss the range of recent developments in optical label-free detection and imaging schemes that offer single-molecule sensitivity, with an emphasis on plasmonically enhanced and scattering-based approaches. …”
    Journal article
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