Advances in the understanding of IgM monoclonal gammopathy of undetermined significance [version 1; referees: 2 approved] by Jonas Paludo, Stephen M Ansell

“…Among monoclonal gammopathies of undetermined significance (MGUSs), the immunoglobulin M (IgM) MGUS subtype stands as a unique entity and plays a pivotal role as a pre-malignant condition for multiple B-cell non-Hodgkin lymphomas, most notably Waldenström macroglobulinemia (WM). …”
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PARAPROTEINEMIC POLYNEUROPATHY ASSOCIATED WITH MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE: СLINICAL CASE DESCRIPTION AND LITERATURE REVIEW by A. A. Yakovlev, E. S. Tarabanova, A. G. Smochilin, R. A. Gapeshin, M. V. Yakovleva

“…Monoclonal gammopathy of undetermined significance represents a number of conditions, the development of which is based on functional impairment of B-lymphocytes, which results in permanent pathological secretion of a single clone of immunoglobulins or their constituent chains. …”
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Differences in Hospital, Emergency Room and Outpatient Visits Among Adults With and Without Monoclonal Gammopathy of Undetermined Significance by Maira A. Castañeda-Avila PhD, Kate L. Lapane PhD, Sharina D. Person PhD, Bill M. Jesdale PhD, Yanhua Zhou MS, Kathleen M. Mazor EdD, Mara M. Epstein ScD

“…Introduction This study evaluated the impact of receiving a monoclonal gammopathy of undetermined significance (MGUS) diagnosis on healthcare utilization from patients at a community-based multispecialty provider organization. …”
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Accuracy and Reliability of Internet Resources for Information on Monoclonal Gammopathy of Undetermined Significance—What Information Is out There for Our Patients? by Emma Pauline Kreutzer, Sandra Sauer, Mark Kriegsmann, Henrike Staemmler, Gerlinde Egerer, Katharina Kriegsmann

Subjects: “…monoclonal gammopathy of undetermined significance (MGUS)…”
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Progression patterns in monoclonal gammopathy of undetermined significance and multiple myeloma outcome: a cohort study in 42 patients by Widad Tahiru, Antonio Izarra Santamaria, Johan Hultdin, Wendy Yi-Ying Wu, Florentin Späth

“…Abstract Follow-up of low-risk monoclonal gammopathy of undetermined significance (MGUS) is debated as multiple myeloma (MM) progression risk is low. …”
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Sporadic late onset nemaline myopathy with monoclonal gammopathy of undetermined significance: two cases with long term stability by André Truffert, Ruxandra Iancu Ferfoglia, Johannes Alexander Lobrinus, Kaveh Samii, André Kohler

Subjects: “…monoclonal gammopathy of undetermined significance…”
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Impact of whole-body vibration exercise on physical performance and bone turnover in patients with monoclonal gammopathy of undetermined significance by Lothar Seefried, Franca Genest, Johanna Strömsdörfer, Bernhard Engelmann, Constantin Lapa, Franz Jakob, Freerk T. Baumann, Billy Sperlich, Franziska Jundt

Subjects: “…Monoclonal gammopathy of undetermined significance…”
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P931: PROSPECTIVE OBSERVATIONAL MULTICENTER STUDY OF GAUCHER DISEASE PREVALENCE IN PATIENTS AFFECTED BY MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE by G. Giuffrida, U. Markovic, C. Conticello, D. Nicolosi, V. Calafiore, A. Romano, A. Condorelli, S. Grasso, A. Duminuco, M. Calagna, A. Nardo, C. Riccobene, B. Esposito, U. Consoli, V. Di Giacomo, S. Neri, M. R. Cingari, G. Iaria, V. Innao, M. Spina, J. Gentile, C. Zizzo, G. Duro, F. Di Raimondo

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Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6 by Alyssa Clay-Gilmour, Subhayan Chattopadhyay, Michelle A. T. Hildebrandt, Hauke Thomsen, Niels Weinhold, Pavel Vodicka, Ludmila Vodickova, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Börge Schmidt, Christian Langer, Roman Hajek, Göran Hallmans, Ulrika Pettersson-Kymmer, Claes Ohlsson, Florentin Späth, Richard Houlston, Hartmut Goldschmidt, Elisabet E. Manasanch, Aaron Norman, Shaji Kumar, S. Vincent Rajkumar, Susan Slager, Asta Försti, Celine M. Vachon, Kari Hemminki

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A nationwide study of patients with monoclonal gammopathy of undetermined significance with a 10-year follow-up in South Korea by Ka-Won Kang, Ji Eun Song, Byung-Hyun Lee, Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Se Ryeon Lee, Hwa Jung Sung, Chul Won Choi, Yong Park, Byung Soo Kim

“…Abstract In clinical practice, most patients with monoclonal gammopathy of undetermined significance (MGUS) undergo long-term follow-up without disease progression. …”
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Metabolomic and Lipidomic Profiling of Bone Marrow Plasma Differentiates Patients with Monoclonal Gammopathy of Undetermined Significance from Multiple Myeloma by Wilson I. Gonsalves, Katarzyna Broniowska, Erik Jessen, Xuan-Mai Petterson, Alexander Graham Bush, Jaimee Gransee, Martha Q. Lacy, Taro Hitosugi, Shaji K. Kumar

“…Abstract Oncogenic drivers of progression of monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) such as c-MYC have downstream effects on intracellular metabolic pathways of clonal plasma cells (PCs). …”
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SARS-CoV-2 Infection Incidence and Outcome Before and After Full Vaccination in Patients With Monoclonal Gammopathy of Undetermined Significance by Nicola Sgherza, Daniela Di Gennaro, Paola Curci, Rita Rizzi, Daniela Roccotelli, Maria Croce, Martina Avantaggiato, Loredana Ruga, Vanda Strafella, Angelantonio Vitucci, Antonio Palma, Antonella V. Russo Rossi, Teresa Troiano, Angela M. V. Larocca, Maria Chironna, Silvio Tafuri, Francesco Albano, Pellegrino Musto

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Regression of Intermediate-High Risk Monoclonal Gammopathy of Undetermined Significance (MGUS) With Long-term Use of Curcumin: A Case Report by Terry Golombick PhD, Dipl Nut, Rajeev Ramakrishna MPH, FRACP, FRCPA, Arumugam Manoharan MD, FRACP, FRCPA

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P29: EFFECTS OF VACCINATION ON INCIDENCE AND OUTCOME OF SARS-COV-2 INFECTION IN PATIENTS WITH MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS) by N Sgherza, R Rizzi, P Curci, D Roccotelli, M Croce, M Avantaggiato, L Ruga, P Musto

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P950: PRIOR CANCER AND RISK OF MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS): A POPULATION-BASED STUDY IN ICELAND AND SWEDEN by Sæmundur Rögnvaldsson, Sigrún Þorsteinsdóttir, Elisavet Syriopoulou, Ingigerdur Solveig Sverrisdottir, Ingemar Turesson, Elías Eyþórsson, Guðrún Ásta Sigurðardóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni Agnar Agnarsson, Margrét Sigurðadóttir, Ísleifur Ólafsson, Ingunn Þorsteinsdóttir, Robert Palmason, Jon Thorir Oskarsson, Ásdís Rósa Þórðardóttir, Ásbjörn Jónsson, Runólfur Pálsson, Ólafur Skúli Indriðason, Thor Aspelun, Hannah Bower, Gauti Kjartan Gíslason, Andri Ólafsson, Jón Kristinn Sigurðsson, Þórir Einarsson Long, Malin Hultcrantz, Brian Durie, Stephen Harding, Magnus Bjorkholm, C. Ola Landgren, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson

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Type-I Cryoglobulinaemia Associated to Monoclonal Gammapathy of Undetermined Significance by Juan Manuel Duarte, Paloma Ocampo, Silvia Graciela Ramos, Orlando Gabriel Carballo, Ricardo E. Barcia, Cecilia Elena Arévalo

Subjects: “…monoclonal gammopathy of undetermined significance…”
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Pro-inflammatory State in Monoclonal Gammopathy of Undetermined Significance and in Multiple Myeloma Is Characterized by Low Sialylation of Pathogen-Specific and Other Monoclonal Immunoglobulins by Adrien Bosseboeuf, Sophie Allain-Maillet, Nicolas Mennesson, Anne Tallet, Cédric Rossi, Laurent Garderet, Laurent Garderet, Laurent Garderet, Denis Caillot, Philippe Moreau, Eric Piver, Eric Piver, François Girodon, Hélène Perreault, Sophie Brouard, Arnaud Nicot, Edith Bigot-Corbel, Edith Bigot-Corbel, Edith Bigot-Corbel, Sylvie Hermouet, Sylvie Hermouet, Sylvie Hermouet, Jean Harb, Jean Harb, Jean Harb, Jean Harb

Subjects: “…monoclonal gammopathy of undetermined significance…”
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The “Undetermined Significance” of ¹⁸F-FDG PET/CT or PET/MRI in Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS) by Giorgio Treglia, Francesco Bertagna, Domenico Albano

“…Monoclonal gammopathy of undetermined significance (MGUS) is a highly prevalent condition with the possible risk of progression to multiple myeloma (MM) or a lymphoproliferative neoplasm in a small percentage of patients. …”
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Incidentally Detected Amyloid Light-Chain Amyloidosis Caused by Monoclonal Gammopathy of Undetermined Significance: Possible Time-Dependent Change in Colonic Findings by Toshiro Fukui, Yuji Tanimura, Yasushi Matsumoto, Shunsuke Horitani, Takashi Tomiyama, Kazuichi Okazaki

Subjects: “…Monoclonal gammopathy of undetermined significance…”
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Outcomes of Patients with Monoclonal Gammopathy of Undetermined Significance with and without Atrial Fibrillation: A Retrospective Cohort Analysis of the Nationwide Inpatient Sample Database by Rachelle Hamadi, Zakaria Alameddine, Samer Asmar, Fouad Sakr, Hussam Aridi, Reem Dimachkie, Hadi Skouri

“…Background: Monoclonal gammopathy of undetermined significance (MGUS) is a non-malignant precursor of multiple myeloma (MM). …”
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