Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD by Jared R. Williams, Emiliano Trias, Pamela R. Beilby, Nathan I. Lopez, Edwin M. Labut, C. Samuel Bradford, Blaine R. Roberts, Erin J. McAllum, Peter J. Crouch, Timothy W. Rhoads, Cliff Pereira, Marjatta Son, Jeffrey L. Elliott, Maria Clara Franco, Alvaro G. Estévez, Luis Barbeito, Joseph S. Beckman

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A Therapeutic Strategy for Lower Motor Neuron Disease and Injury Integrating Neural Stem Cell Transplantation and Functional Electrical Stimulation in a Rat Model by Katsuhiro Tokutake, Masaru Takeuchi, Shigeru Kurimoto, Sota Saeki, Yuta Asami, Keiko Onaka, Masaomi Saeki, Tadayoshi Aoyama, Yasuhisa Hasegawa, Hitoshi Hirata

“…Promising treatments for upper motor neuron disease are emerging in which motor function is restored by brain–computer interfaces and functional electrical stimulation. …”
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Genetic model of motor neuron disease in B6SJL-Tg mice: new data on the dynamics of motor symptoms and immunohistochemical manifestations of the neurodegenerative process by А. V. Stavrovskaya, D. N. Voronkov, E. A. Artyomova, B. V. Belugin, М. М. Shmarov, N. G. Yamshchikova, А. S. Gushchina, А. S. Olshansky, B. S. Naroditskiy, S. N. Illarioshkin

“…Over the past several decades, the study of mutations associated with motor neuron disease has led to the development of a number of transgenic animal models of motor neuron disease. …”
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Strategy for Treating Motor Neuron Diseases Using a Fusion Protein of Botulinum Toxin Binding Domain and Streptavidin for Viral Vector Access: Work in Progress by Uma Balasubramanian, Yang Lu, Daniel B. Drachman, Robert N. Adams

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Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease by Vincent Soubannier, Mathilde Chaineau, Lale Gursu, Ghazal Haghi, Anna Kristyna Franco Flores, Guy Rouleau, Thomas M. Durcan, Stefano Stifani

“…Dysfunctions of astrocytes are associated with numerous disorders and diseases of the nervous system, including motor neuron diseases such as amyotrophic lateral sclerosis (ALS). …”
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Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases. by Lydia K Muranova, Stephen D Weeks, Sergei V Strelkov, Nikolai B Gusev

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An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease by Sandra Anne Banack, Rachael Anne Dunlop, Paul Alan Cox

“…Biomarkers for amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) are currently not clinically available for disease diagnosis or analysis of disease progression. …”
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Homocysteine aggravates ROS-induced depression of transmitter release from motor nerve terminals: potential mechanism of peripheral impairment in motor neuron diseases associated with hyperhomocysteinemia by Ellya eBukharaeva, Ellya eBukharaeva, Anastasia eShakirzyanova, Anastasia eShakirzyanova, Venera eKhuzakhmetova, Guzel eSitdikova, Rashid eGiniatullin, Rashid eGiniatullin

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Adult-onset non-5q proximal spinal muscular atrophy: a comprehensive review by Wladimir Bocca Vieira de Rezende Pinto, Paulo Victor Sgobbi de Souza, Bruno Mattos Lombardi Badia, Igor Braga Farias, José Marcos Vieira de Albuquerque Filho, Eduardo Augusto Gonçalves, Roberta Ismael Lacerda Machado, Acary Souza Bulle Oliveira

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Comparative Assessment of Robotic versus Classical Physical Therapy Using Muscle Strength and Ranges of Motion Testing in Neurological Diseases by Zoltán Zsigmond Major, Calin Vaida, Kinga Andrea Major, Paul Tucan, Emanuela Brusturean, Bogdan Gherman, Iosif Birlescu, Raul Craciunaș, Ionut Ulinici, Gábor Simori, Alexandru Banica, Nicoleta Pop, Alin Burz, Giuseppe Carbone, Doina Pisla

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GNX-4728, a Novel Small Molecule Drug Inhibitor of Mitochondrial Permeability Transition, is Therapeutic in a Mouse Model of Amyotrophic Lateral Sclerosis by Lee J Martin, Daniele eFancelli, Margaret eWong, Mark eNiedzwiecki, Marco eBallarini, Simon ePlyte, Qing eChang

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Cerebellar remodelling decades after spinal cord insult: neuroplasticity in poliomyelitis survivors by Stacey Li Hi Shing, Aizuri Murad, Jasmin Lope, Orla Hardiman, Peter Bede

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Pilot Experiments and Hardware Design of Smart Electrooculographic Headband for People With Muscular Paralysis by Helena Kosnacova, Dusan Horvath, Maximilian Stremy, Michal Sobota, Patrik Bartos, Martin Jagelka, Tomas Zavodnik, Diana Vitazkova, Erik Foltan, Neven Vrcek, Erik Vavrinsky

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A Multi-Center Cohort Study on Characteristics of Pain, Its Impact and Pharmacotherapeutic Management in Patients with ALS by Susanne Vogt, Ina Schlichte, Stefanie Schreiber, Bernadette Wigand, Grazyna Debska-Vielhaber, Johanna Heitmann, Thomas Meyer, Reinhard Dengler, Susanne Petri, Aiden Haghikia, Stefan Vielhaber

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Anthropometry of arm: nutritional risk indicator in amyotrophic lateral sclerosis by Cristina Cleide dos Santos Salvioni, Patricia Stanich, Acary Souza Bulle Oliveira, Marco Orsini

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ALS or ALS mimic by neuroborreliosis—A case report by Isabelle Wirsching, Nora Ort, Nurcan Üçeyler

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ALS/FTD: Evolution, Aging, and Cellular Metabolic Exhaustion by Robert David Henderson, Kasper Planeta Kepp, Andrew Eisen

Subjects: “…motor neuron disease…”
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A Strength Endurance Exercise Paradigm Mitigates Deficits in Hypoglossal-Tongue Axis Function, Strength, and Structure in a Rodent Model of Hypoglossal Motor Neuron Degeneration by Erika R. Murphy, Rebecca Thompson, Rebecca Thompson, Kate L. Osman, Chandler Haxton, Margaret Brothers, Li Lee, Li Lee, Kristen Warncke, Kristen Warncke, Catherine L. Smith, Amy N. Keilholz, Ali Hamad, Mojgan Golzy, Filiz Bunyak, Lixin Ma, Lixin Ma, Nicole L. Nichols, Nicole L. Nichols, Teresa E. Lever, Teresa E. Lever, Teresa E. Lever

Subjects: “…motor neuron disease (MND)…”
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Environmental exposure to metals and the development of tauopathies, synucleinopathies, and TDP-43 proteinopathies: A systematic evidence map protocol by Kirstin Hester, Ellen Kirrane, Timothy Anderson, Nichole Kulikowski, Jane Ellen Simmons, David M. Lehmann

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Commentary: FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons by Bert M. Verheijen, R. Jeroen Pasterkamp

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