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    Riluzole use in presence of contraindications in adults affected by amyotrophic lateral sclerosis and its off-label use in other motor neuron diseases: Findings from an Italian multicentre study (the CAESAR project) by Giada Crescioli, Giada Crescioli, Marco Finocchietti, Silvia Cascini, Olga Paoletti, David Franchini, Emiliano Cappello, Giulia Valdiserra, Francesco Sciancalepore, Maria Grazia Celani, Marco Tuccori, Marco Tuccori, Alfredo Vannacci, Alfredo Vannacci, Niccolò Lombardi, Niccolò Lombardi, Ursula Kirchmayer, the CAESAR Study Group

    Published 2022-10-01
    “…Background: This analysis describes the use of riluzole in amyotrophic lateral sclerosis (ALS) individuals with contraindications and off-label use for subjects with other motor neuron diseases (o-MND) in the Italian regions of Latium, Tuscany and Umbria.Methods: A cohort of adults with ALS prescribed with riluzole during the years 2016–2019 was enrolled from administrative healthcare databases, excluding subjects with o-MND in the preceding 5 years. …”
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