Advanced Gene-Targeting Therapies for Motor Neuron Diseases and Muscular Dystrophies by Myrsini Chamakioti, Nikolaos Karantzelis, Stavros Taraviras

“…Gene therapy is a revolutionary, cutting-edge approach to permanently ameliorate or amend many neuromuscular diseases by targeting their genetic origins. Motor neuron diseases and muscular dystrophies, whose genetic causes are well known, are the frontiers of this research revolution. …”
Get full text

A Case of Motor Neuron Disease Following Covid-19 Vaccination by Mohadeseh Farokhfar

Subjects: Get full text

Dementia as a presentation of motor neurone disease: a case report by A. S. C. Miranda, I. Franco, J. Miranda

“… Introduction Amyotrophic lateral sclerosis (ALS), the most common disease within motor neuron diseases (MND), and frontotemporal dementia (FTD) belong to a broad spectrum of neurodegenerative diseases that are sometimes clinically overlapping. …”
Get full text

Metaphoric language and the articulation of emotions by people affected by motor neurone disease. by Locock, L, Mazanderani, F, Powell, J

“… OBJECTIVE: To explore the use of metaphoric language to convey emotion in interviews with people affected by motor neurone disease, a progressive neurological condition that sits between chronic and terminal illness. …”

Vitamin B12 deficiency mimicking neuroimaging features of motor neuron disease by Wladimir Bocca Vieira de Rezende Pinto, Paulo Victor Sgobbi de Souza, Ricardo Mendes Rogério, José Luiz Pedroso, Orlando Graziani Povoas Barsottini

Get full text

Why should we care about astrocytes in a motor neuron disease? by Katarina Stoklund Dittlau, Katarina Stoklund Dittlau, Ludo Van Den Bosch, Ludo Van Den Bosch

“…Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in adults, causing progressive degeneration of motor neurons, which results in muscle atrophy, respiratory failure and ultimately death of the patients. …”
Get full text

Corneal confocal microscopy in the evaluation of immune-related motor neuron disease syndrome by Lin Jiao, Yuanjin Zhang, Haikun Wang, Dongsheng Fan

Subjects: “…Motor neuron disease…”
Get full text

Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research? by Kurt J. De Vos, Majid Hafezparast

Subjects: “…Motor neuron disease…”
Get full text

Disruption of Neuromuscular Junction Following Spinal Cord Injury and Motor Neuron Diseases by Colin Nemeth, Naren L. Banik, Azizul Haque

Get full text

A Road Map for Remote Digital Health Technology for Motor Neuron Disease by Ruben P A van Eijk, Anita Beelen, Esther T Kruitwagen, Deirdre Murray, Ratko Radakovic, Esther Hobson, Liam Knox, Jochem Helleman, Tom Burke, Miguel Ángel Rubio Pérez, Evy Reviers, Angela Genge, Frederik J Steyn, Shyuan Ngo, John Eaglesham, Kit C B Roes, Leonard H van den Berg, Orla Hardiman, Christopher J McDermott

“…Given the ever-changing care needs of patients and the relentless progression rate of motor neuron disease, the adoption of digital health care technology will significantly benefit the delivery of care and accelerate the development of effective treatments.…”
Get full text

Sjögren’s syndrome with rapidly progressive motor neuron disease: a case report by Huijia Yang, Xiaozhong Jing, Jinhua Yan, Dihui Ma

“…Sjögren’s syndrome with motor neuron disease is rarely reported. Herein, we describe a patient with rapidly progressive motor neuron disease secondary to Sjögren’s syndrome. …”
Get full text

Profiling morphologic MRI features of motor neuron disease caused by TARDBP mutations by Edoardo Gioele Spinelli, Edoardo Gioele Spinelli, Alma Ghirelli, Alma Ghirelli, Alma Ghirelli, Nilo Riva, Nilo Riva, Elisa Canu, Veronica Castelnovo, Teuta Domi, Laura Pozzi, Paola Carrera, Vincenzo Silani, Vincenzo Silani, Adriano Chiò, Massimo Filippi, Massimo Filippi, Massimo Filippi, Massimo Filippi, Massimo Filippi, Federica Agosta, Federica Agosta, Federica Agosta

Subjects: “…motor neuron disease (MND)…”
Get full text

Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy by Subhavi De Silva, Bradley J. Turner, Nirma D. Perera

Get full text

Neurofilaments in CSF as diagnostic biomarkers in motor neuron disease: a meta-analysis by Dawei Li, Dongchao Shen, Hongfei Tai, Liying Cui, Liying Cui

Subjects: Get full text

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA by Tomohiro Yamazaki, Shi Chen, Yong Yu, Biao Yan, Tyler C. Haertlein, Monica A. Carrasco, Juan C. Tapia, Bo Zhai, Rita Das, Melanie Lalancette-Hebert, Aarti Sharma, Siddharthan Chandran, Gareth Sullivan, Agnes Lumi Nishimura, Christopher E. Shaw, Steve P. Gygi, Neil A. Shneider, Tom Maniatis, Robin Reed

“…Mutations in the RNA binding protein FUS cause amyotrophic lateral sclerosis (ALS), a fatal adult motor neuron disease. Decreased expression of SMN causes the fatal childhood motor neuron disorder spinal muscular atrophy (SMA). …”
Get full text

Amyotrophic Lateral Sclerosis: A Neurodegenerative Motor Neuron Disease With Ocular Involvement by Pilar Rojas, Pilar Rojas, Ana I. Ramírez, Ana I. Ramírez, Ana I. Ramírez, José A. Fernández-Albarral, Inés López-Cuenca, Elena Salobrar-García, Elena Salobrar-García, Elena Salobrar-García, Manuel Cadena, Lorena Elvira-Hurtado, Juan J. Salazar, Juan J. Salazar, Juan J. Salazar, Rosa de Hoz, Rosa de Hoz, Rosa de Hoz, José M. Ramírez, José M. Ramírez, José M. Ramírez

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes degeneration of the lower and upper motor neurons and is the most prevalent motor neuron disease. This disease is characterized by muscle weakness, stiffness, and hyperreflexia. …”
Get full text

Neurometabolic Alterations in Motor Neuron Disease: Insights from Magnetic Resonance Spectroscopy by Foteini Christidi, Efstratios Karavasilis, Georgios D. Argyropoulos, Georgios Velonakis, Vasiliki Zouvelou, Aizuri Murad, Ioannis Evdokimidis, Michail Rentzos, Ioannis Seimenis, Peter Bede

Subjects: Get full text

A plural role for lipids in motor neuron diseases: energy, signaling and structure. by Florent eSCHMITT, Florent eSCHMITT, Ghulam eHUSSAIN, Ghulam eHUSSAIN, Luc eDupuis, Luc eDupuis, Jean-Philippe eLoeffler, Jean-Philippe eLoeffler, Alexandre eHenriques, Alexandre eHenriques

“…Motor neuron diseases (MNDs) are characterized by selective death of motor neurons and include mainly adult-onset amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). …”
Get full text

Relationship between oral transit time and functional performance in motor neuron disease by Bárbara Carolina Brandão, Magali Aparecida Orate Menezes da Silva, Paula Cristina Cola, Roberta Gonçalves da Silva

“…ABSTRACT Oral phase swallowing impairment in motor neuron disease (MND) is caused by tongue weakness, fasciculation and atrophy, which may compromise oral transit time and total feeding time. …”
Get full text

A case report: Ayurvedic intervention in motor neuron disease contemplating Kaphavrutavata by Basavaraj V. Policepatil

Subjects: Get full text