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201
Phenomenological model of motility by spatiotemporal modulation of active interactions
Published 2021-01-01“…Recent experiments achieved self-organized transport phenomena in microtubule active matter using light to modulate motor-protein activity in time and space. Here, we introduce a novel phenomenological model to explain such experiments. …”
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202
Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei.
Published 2010-08-01“…Myosins are a multimember family of motor proteins with diverse functions in eukaryotic cells. …”
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Article -
203
Myosin XI is required for actin-associated movement of plastid stromules.
Published 2009“…Experiments with inhibitors of cytoskeleton assembly have indicated the involvement of an actin-based system in stromule movement. However, the motor protein associated with the system had not been identified. …”
Journal article -
204
Cenp-meta is required for sustained spindle checkpoint
Published 2014-05-01“…Cenp-E is a kinesin-like motor protein required for efficient end-on attachment of kinetochores to the spindle microtubules. …”
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205
Mud binds the kinesin-14 Ncd in Drosophila
Published 2021-07-01“…Our results describe an interaction between two spindle-associated proteins and suggest a potentially new mode of minus-end motor protein regulation at mitotic spindle poles.…”
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206
Common mechanisms underlying axonal transport deficits in neurodegenerative diseases: a mini review
Published 2023-04-01“…The mechanisms can be summarized as follows: (1) motor protein changes including expression levels and post-translational modification alteration; (2) changes in microtubules including reducing stability and disrupting tracks; (3) changes in cargoes including diminished binding to motor proteins. …”
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207
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling
Published 2017-01-01“…Here the authors identify the kinesin-3 motor protein KIF13B as a regulator of TZ membrane composition that controls the ciliary accumulation of Smoothened, which is involved in activation of Sonic hedgehog signalling.…”
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208
Intra-bundle contractions enable extensile properties of active actin networks
Published 2021-01-01“…We reconstituted a minimal cortex adhered to a model cell membrane mimicking two processes mediated by the motor protein myosin: contractility and high turnover of actin monomers. …”
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209
IIb or not IIb? Regulation of myosin heavy chain gene expression in mice and men
Published 2011-02-01“…<p>Abstract</p> <p>Background</p> <p>While the myosin heavy chain IIb isoform (MyHC-IIb) is the predominant motor protein in most skeletal muscles of rats and mice, the messenger RNA (mRNA) for this isoform is only expressed in a very small subset of specialized muscles in adult large mammals, including humans.…”
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210
Miro1 depletion disrupts spatial distribution of mitochondria and leads to oocyte maturation defects
Published 2022-10-01“…Mitochondria remain capable of long-range trafficking during maturation, indicating redundancy in the mechanisms coupling mitochondria to motor proteins. Polar body extrusion in the absence of MIRO1 was reduced by approximately 20%. …”
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211
Analysis of mitochondrial organization and function in the Drosophila blastoderm embryo
Published 2017-07-01“…We find that mitochondria are relatively small, dispersed and distinctly distributed along the apico-basal axis in proximity to microtubules by motor protein transport. Live imaging, photobleaching and photoactivation analyses of mitochondrially targeted GFP show that they are mobile in the apico-basal axis along microtubules and are immobile in the lateral plane thereby associating with one syncytial cell. …”
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212
Mechanisms of Spindle Positioning: Lessons from Worms and Mammalian Cells
Published 2019-02-01“…In metazoans, the key players that regulate proper spindle positioning are the actin-rich cell cortex and associated proteins, the ternary complex (Gα/GPR-1/2/LIN-5 in <i>Caenorhabditis elegans</i>, Gαi/Pins/Mud in <i>Drosophila</i> and Gαi<sub>1-3</sub>/LGN/NuMA in humans), minus-end-directed motor protein dynein and the cortical machinery containing myosin. …”
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213
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214
RNAi screen for proteasome and cytoskeletal proteins affecting dendrite remodeling during drosophila metamorphosis.
Published 2009“…This indicates that the proteasome is involved in downstream event of EcR signaling during dendrite remodeling. The RNAi of a motor protein (Unc-104) showed abnormal dendrite morphology and pruning defect at white pupa stage and 18 hr APF respectively. …”
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Final Year Project (FYP) -
215
To study yeast actin cytoskeleton involved in endocytosis and actin cable using optigenetics
Published 2016“…On the other hand, actin cable plays vital role in transporting the cargo into and within the cell with the help of motor protein called Myo2. Actin cables are nucleated by formins called Bni1 and Bnr1. …”
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Thesis -
216
Spontaneous rotation of active droplets in two and three dimensions
Published 2023“…We compare our results on rotation in two-dimensional droplets with experiments on microtubule and motor protein suspensions and find a critical radius approximately equal to <span tabindex="0">700µm</span>, above which the spontaneous rotation gives way to active turbulence. …”
Journal article -
217
The toxoplasma Acto-MyoA motor complex is important but not essential for gliding motility and host cell invasion
Published 2014“…Recent studies demonstrated that Toxoplasma gondii can invade the host cell in the absence of several core components of the invasion machinery, such as the motor protein myosin A (MyoA), the microneme proteins MIC2 and AMA1 and actin, indicating the presence of alternative invasion mechanisms. …”
Journal article -
218
Snapin promotes HIV‐1 transmission from dendritic cells by dampening TLR8 signaling
Published 2017“…A secondary siRNA screen of the identified signaling factors revealed several new mediators of HIV-1 trans-infection of CD4+ T cells in DCs, including the dynein motor protein Snapin. Inhibition of Snapin enhanced localization of HIV-1 with TLR8+ early endosomes, triggered a pro-inflammatory response, and inhibited trans-infection of CD4+ T cells. …”
Journal article -
219
Extrusion without a motor: a new take on the loop extrusion model of genome organization
Published 2018“…However, the model requires a motor to generate the loops, and although cohesin is a strong candidate for the extruding factor, a suitable motor protein (or a motor activity in cohesin itself) has yet to be found. …”
Journal article -
220
In Vitro Interaction of the Housekeeping SecA1 with the Accessory SecA2 Protein of Mycobacterium tuberculosis.
Published 2015-01-01“…The majority of proteins that are secreted across the bacterial cytoplasmic membrane leave the cell via the Sec pathway, which in its minimal form consists of the dimeric ATP-driven motor protein SecA that associates with the protein-conducting membrane pore SecYEG. …”
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