The Proliferation of Glioblastoma Is Contributed to Kinesin Family Member 18A and Medical Data Analysis of GBM by Lei-Bo Wang, Xue-Bin Zhang, Jun Liu, Qing-Jun Liu

“…Targeted therapy has shown great promise in treating glioblastoma, but more promising targets, including effective therapeutic targets, remain to be identified. 18A (KIF18A) is a microtubule-based motor protein that is dysregulated and involved in the progression of multiple human cancers. …”
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RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis. by Miguel Hernandez Sanchez-Rebato, Alida M Bouatta, Maria E Gallego, Charles I White, Olivier Da Ines

“…An essential component of the homologous recombination machinery in eukaryotes, the RAD54 protein is a member of the SWI2/SNF2 family of helicases with dsDNA-dependent ATPase, DNA translocase, DNA supercoiling and chromatin remodelling activities. It is a motor protein that translocates along dsDNA and performs multiple functions in homologous recombination. …”
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Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development by Wen-Xin Yu, Yu-Kun Li, Meng-Fei Xu, Chen-Jie Xu, Jie Chen, Ya-Lan Wei, Zhen-Yu She

“…Kinesin-5 Eg5 is a plus-end-directed kinesin motor protein, which is essential for spindle pole separation and chromosome alignment in mitosis. …”
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FliL Functions in Diverse Microbes to Negatively Modulate Motor Output via Its N-Terminal Region by Xiaolin Liu, Anna Roujeinikova, Karen M. Ottemann

“…ABSTRACT The flagellar motor protein FliL is conserved across many microbes, but its exact role has been obscured by varying fliL mutant phenotypes. …”
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Prion Aggregates Are Recruited to the Insoluble Protein Deposit (IPOD) via Myosin 2-Based Vesicular Transport. by Rajesh Kumar, Peter P Nawroth, Jens Tyedmers

“…Thus we propose a model where vesicles, loaded with preApe1 or PrD-GFP, are recruited to tropomyosin coated actin cables via the Myo2 motor protein for delivery to the PAS and IPOD, respectively. …”
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YTHDF2 facilitates aggresome formation via UPF1 in an m6A-independent manner by Hyun Jung Hwang, Tae Lim Park, Hyeong-In Kim, Yeonkyoung Park, Geunhee Kim, Chiyeol Song, Won-Ki Cho, Yoon Ki Kim

“…Subsequently, YTHDF2 increases the interaction between the dynein motor protein and the misfolded polypeptide-associated complex, facilitating the diffusion dynamics of the movement of misfolded polypeptides toward aggresomes. …”
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Direct imaging of RAB27B-enriched secretory vesicle biogenesis in lacrimal acinar cells reveals origins on a nascent vesicle budding site. by Lilian Chiang, Serhan Karvar, Sarah F Hamm-Alvarez

“…Finally, YFP-Rab27b-enriched secretory vesicles which reached the subapical cytoplasm appeared to acquire the actin-based motor protein, Myosin 5C. Our findings show that Rab27b enrichment occurs early in secretory vesicle formation, that secretory vesicles bud from a visually discernable nascent vesicle site, and that transport from the nascent vesicle site to the subapical region requires intact microtubules.…”
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Interplay between myosin II and actin dynamics in chemotactic amoeba by H F Hsu, A Krekhov, M Tarantola, C Beta, E Bodenschatz

“…One of the key players that governs the dynamics of the actin network is the motor protein myosin II. Based on a phase space embedding we have identified from experiments three phases in the cytoskeletal dynamics of starved Dictyostelium discoideum in response to a precisely controlled chemotactic stimulation. …”
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Local Somatodendritic Translation and Hyperphosphorylation of Tau Protein Triggered by AMPA and NMDA Receptor Stimulation by Shunsuke Kobayashi, Toru Tanaka, Yoshiyuki Soeda, Osborne F.X. Almeida, Akihiko Takashima

“…Further, we show that Tau mRNA is a component of mRNP granules that contain RNA-binding proteins, and that it interacts with Myosin Va, a postsynaptic motor protein; these findings suggest that tau mRNA is transported into dendritic spines. …”
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Nanoparticles engineered to bind cellular motors for efficient delivery by Inmaculada Dalmau-Mena, Pablo del Pino, Beatriz Pelaz, Miguel Ángel Cuesta-Geijo, Inmaculada Galindo, María Moros, Jesús M. de la Fuente, Covadonga Alonso

“…Abstract Background Dynein is a cytoskeletal molecular motor protein that transports cellular cargoes along microtubules. …”
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Comparative genomic analysis of the ‘pseudofungus’ Hyphochytrium catenoides by Guy Leonard, Aurélie Labarre, David S. Milner, Adam Monier, Darren Soanes, Jeremy G. Wideman, Finlay Maguire, Sam Stevens, Divya Sain, Xavier Grau-Bové, Arnau Sebé-Pedrós, Jason E. Stajich, Konrad Paszkiewicz, Matthew W. Brown, Neil Hall, Bill Wickstead, Thomas A. Richards

“…Comparative genomics also identified differences in the repertoire of genes associated with filamentous growth between the Fungi and the Pseudofungi, including differences in vesicle trafficking systems, cell-wall synthesis pathways and motor protein repertoire, demonstrating that unique cellular systems underpinned the convergent evolution of filamentous osmotrophic growth in these two eukaryotic groups.…”
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Rotary properties of hybrid F1-ATPases consisting of subunits from different species by Ryo R. Watanabe, Busra Tas Kiper, Mariel Zarco-Zavala, Mayu Hara, Ryohei Kobayashi, Hiroshi Ueno, José J. García-Trejo, Chun-Biu Li, Hiroyuki Noji

“…Summary: F1-ATPase (F1) is an ATP-driven rotary motor protein ubiquitously found in many species as the catalytic portion of FoF1-ATP synthase. …”
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Kinetic modeling of the assembly, dynamic steady state, and contraction of the FtsZ ring in prokaryotic cytokinesis. by Ivan V Surovtsev, Jeffrey J Morgan, Paul A Lindahl

“…The model suggests a possible mechanism of membrane contraction without a motor protein. The portion of the free energy of GTP hydrolysis released in cyclization is indirectly used in this energetically unfavorable process. …”
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The Amyloid Precursor Protein of Alzheimer's Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner. by James W Stevenson, Eliza A Conaty, Rylie B Walsh, Paul J Poidomani, Colin M Samoriski, Brianne J Scollins, Joseph A DeGiorgis

“…In addition, the association of APP-organelles with microtubules is an ATP dependent process suggesting that the APP-organelles contain a microtubule-based motor protein. Although a direct kinesin/APP association remains controversial, the distribution of APP at the organelle/microtubule interface strongly suggests that APP-organelles have an orientation and that APP like the Alzheimer's protein tau has a microtubule-based function.…”
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Cytoplasmic Travels of the Ecdysteroid Receptor in Target Cells: Pathways for both Genomic and Non-Genomic Actions by Xanthe eVafopoulou, Colin G.H. Steel

“…EcR also forms intimate associations with the chaperone Hsp90, the immunophilin FKBP52 and the light chain 1 of the motor protein dynein. All these factors also associate with MTs. …”
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Myosin Va and Endoplasmic Reticulum Calcium Channel Complex Regulates Membrane Export during Axon Guidance by Fumitaka Wada, Asuka Nakata, Yoshiro Tatsu, Noriko Ooashi, Tetsuko Fukuda, Takuji Nabetani, Hiroyuki Kamiguchi

“…The Ca2+-dependent motor protein myosin Va (MyoVa) tethers membrane vesicles to the ER via a common binding site on the two major ER Ca2+ channels, inositol 1,4,5-trisphosphate and ryanodine receptors. …”
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Acoustic input and efferent activity regulate the expression of molecules involved in cochlear micromechanics by Verónica eLamas, Juan Carlos Arevalo, Juan Carlos Arevalo, José M Juíz, Miguel A Merchán, Miguel A Merchán

“…It relies on the highly specialized membrane motor protein prestin, and its interactions with the cytoskeleton. …”
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Immunolocalization of dynein, dynactin, and kinesin in the cerebral tissue as a possible supplemental diagnostic tool for traumatic brain injury in postmortem examination by Mieszko Olczak, Łukasz Poniatowski, Magdalena Kwiatkowska, Dorota Samojłowicz, Sylwia Tarka, Teresa Wierzba-Bobrowicz

“…In our study, we documented that DNAH9, DCTN1, and KIF5B staining should be considered as a supplemental diagnostic tool for TBI in postmortem neuropathological examination and forensic autopsy. This additional motor protein immunohistochemical staining procedure could be useful in the evaluation of lesions that may remain undiagnosed during a routine examination and aid in more accurate identification of TBI followed by TAI.…”
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Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy by Alan J. Russell, Mike DuVall, Ben Barthel, Ying Qian, Angela K. Peter, Breanne L. Newell-Stamper, Kevin Hunt, Sarah Lehman, Molly Madden, Stephen Schlachter, Ben Robertson, Ashleigh Van Deusen, Hector M. Rodriguez, Carlos Vera, Yu Su, Dennis R. Claflin, Susan V. Brooks, Peter Nghiem, Alexis Rutledge, Twlya I. Juehne, Jinsheng Yu, Elisabeth R. Barton, Yangyi E. Luo, Andreas Patsalos, Laszlo Nagy, H. Lee Sweeney, Leslie A. Leinwand, Kevin Koch

“…A major contributor to this injury is muscle contraction, controlled by the motor protein myosin. However, how muscle contraction and fast muscle fiber damage contribute to the pathophysiology of DMD has not been well characterized. …”
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Remote control of microtubule plus-end dynamics and function from the minus-end by Xiuzhen Chen, Lukas A Widmer, Marcel M Stangier, Michel O Steinmetz, Jörg Stelling, Yves Barral

“…The old SPB recruits the kinesin motor protein Kip2, which then translocates to the plus-end of the emanating microtubules, promotes their extension and delivers dynein into the bud. …”
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