-
481
MALDI-TOF mass spectrometric protein profiling of microvesicles produced by the NK-92 natural killer cell line
Published 2020-08-01“…An intermediate position is occupied by various functional groups, including cytoskeleton and motor proteins; proteins of centrioles; ion channels and their regulators; proteins of the ubiquitin-proteasome pathway of protein degradation; lipid, steroid, and fatty acid metabolism enzymes; nucleic acid base and carbohydrate metabolism enzymes, as well as energy metabolism enzymes and other proteins involved in intermediate metabolism; proteins of the immune response and inflammation; antigens and histocompatibility proteins; cytokines and growth factors; regulators of apoptosis, autophagy, endocytosis, and exocytosis; regulators of the cell cycle and division; regulators of proliferation, cell differentiation, and morphogenesis; regulators of cell adhesion and matrix metabolism; nuclear transport proteins; transposition proteins; DNA replication and repair proteins, as well as inactive proteins. …”
Get full text
Article -
482
The mutational and phenotypic spectrum of TUBA1A-associated tubulinopathy
Published 2019-02-01“…In a three-dimensional protein model, 38.6% of all disease-causing variants including those in the C-terminal region are predicted to affect the binding of microtubule-associated proteins or motor proteins. Genotype-phenotype analysis for recurrent variants showed an overrepresentation of certain clinical features. …”
Get full text
Article -
483
Identification of hub genes and diagnostic efficacy for triple-negative breast cancer through WGCNA and Mendelian randomization
Published 2024-04-01“…GO and KEGG function enrichment analysis indicated that these core genes were related to various biological processes, such as organelle fission, chromosome segregation, nuclear division, mitotic cell cycle phase transition, the cell cycle, amyotrophic lateral sclerosis, and motor proteins. Using STRING and Cytoscape, the top five genes with high degrees were identified as CDC2, CCNB1, CCNA2, TOP2A, and CCNB2. …”
Get full text
Article -
484
Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling.
Published 2023-11-01“…<h4>Background</h4>Kinesin motor proteins transport intracellular cargo, including mRNA, proteins, and organelles. …”
Get full text
Article -
485
A microscopic study of cohesin
Published 2017“…Recent evidence suggests that Smc complexes are motor proteins and their translocation depends on ATP hydrolysis. …”
Thesis -
486
Comparative study of lysine acetylation in Vesicomyidae clam Archivesica marissinica and the manila clam Ruditapes philippinarum: adaptation mechanisms in cold seep environments
Published 2024-10-01“…The results of KEGG enrichment analysis indicated that acetylated proteins are involved in various cellular processes, including tight junction, motor proteins, gap junction, phagosome, cGMP-PKG signaling pathways, endocytosis, glycolysis/gluconeogenesis, among others (p < 0.05 and FDR < 0.25). …”
Get full text
Article -
487
Integrated Profiling Delineated KIF18A as a Significant Biomarker Associated with Both Prognostic Outcomes and Immune Response in Pancreatic Cancer
Published 2025-02-01“…Kai Nan,1,* Lei Zhang,2,* Yujia Zou,3 Zilong Geng,3 Jing Huang,4 Yulong Peng,4 Su Yin,4 Ming Zhang5 1Department of Joint Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710054, People’s Republic of China; 2Department of Pharmacy, Shaanxi Provincial Hospital of Chinese Medicine, Xi’an, Shaanxi, 710003, People’s Republic of China; 3Department of Orthopaedics, The second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710000, People’s Republic of China; 4Department of Rehabilitative Medicine, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, People’s Republic of China; 5Department of General Practice, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710054, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ming Zhang, Department of General Practice, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, 710054, People’s Republic of China, Email zhangminghonghui@yeah.netPurpose: Kinesin family member 18A (KIF18A) is a member of the kinesin-8 family of motor proteins, involved in the progression and metastasis of various tumors. …”
Get full text
Article -
488
Study of the interaction between the influenza A virus polymerase and GTPase Rab11a
Published 2021“…Analysis of the Rab11a interactome further revealed that IAV infection reduces Rab11a binding to Rab11-family interacting partners (Rab11-FIPs), thereby altering the stoichiometry of cytoplasmic motor proteins bound by Rab11a. Using mutant Rab11a in a GST pull-down assay, this study provides the first evidence that IAV RdRP binds to the same site on Rab11a as Rab11-FIPs. …”
Thesis -
489
The DNA methylation status of the vitamin A signaling associated with testicular degeneration induced by long-day photoperiods in Magang geese
Published 2024-08-01“…A total of 3,359 DMR-associated differentially expressed genes (DEG) were identified; functional enrichment analyses revealed that motor proteins, MAPK signaling pathway, ECM-receptor interaction, phagosome, TGF-beta signaling pathway, and calcium signaling might contribute to the testicular regression process. …”
Get full text
Article -
490
DEAD-Box RNA Helicase Family in Physic Nut (<i>Jatropha curcas</i> L.): Structural Characterization and Response to Salinity
Published 2024-03-01“…Helicases, motor proteins present in both prokaryotes and eukaryotes, play a direct role in various steps of RNA metabolism. …”
Get full text
Article -
491
Molecular motors in nanobiotechnology: Protein and DNA based molecular motors: A review
Published 2024-01-01Get full text
Article