Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD by Tetsuhiro Ueda, Toshihide Takeuchi, Nobuhiro Fujikake, Mari Suzuki, Eiko N. Minakawa, Morio Ueyama, Yuzo Fujino, Nobuyuki Kimura, Seiichi Nagano, Akio Yokoseki, Osamu Onodera, Hideki Mochizuki, Toshiki Mizuno, Keiji Wada, Yoshitaka Nagai

“…Knockdown of components of other microtubule-associated motor protein complexes, including dynein and kinesin, also increased the formation of TDP-43 inclusions, indicating that intracellular transport along microtubules plays a key role in TDP-43 pathology. …”
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Molecular Mechanism of Processive Stepping of Kinesin Motors by Ping Xie

“…Kinesin-1 is a motor protein that can step processively on microtubule by hydrolyzing ATP molecules, playing an essential role in intracellular transports. …”
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Purification of tubulin and microtubules from mouse brain by Li Xiangxiao

“…Purified tubulin or microtubules are widely used for in vitro assays related to their function, such as activities of their modifying enzymes and motor protein activity. This paper gave a review for purification tubulin and microtubules (MTs) using two different methods. …”
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Current status on single molecular sequencing based on protein nanopores by Jiawei Shen, Yongyong Shi

“…In this paper, we will review several kinds of protein nanopores used in single molecular sequencing, such as α-hemolysin nanopore, MspA nanopore and membrane-adapted phi29 motor protein nanopore.…”
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Kinesin-1 activity recorded in living cells with a precipitating dye by Simona Angerani, Eric Lindberg, Nikolai Klena, Christopher K. E. Bleck, Charlotte Aumeier, Nicolas Winssinger

“…Monitoring the activity of the processive motor protein kinesin-1 in live cells is currently difficult. …”
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The Cytoskeleton in Papillomavirus Infection by Malgorzata Bienkowska-Haba, Martin Sapp

“…Following internalization, retrograde transport along microtubules via the dynein motor protein complex is observed. In addition, viral minichromosomes depend on the host cell machinery for partitioning of viral genomes during mitosis, which may be affected by oncoproteins E6 and E7 of high-risk human PV types. …”
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Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models by Karthikeyan Selvarasu, Abhay Kumar Singh, Ashok Iyaswamy, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Amal Kanti Bera, Jian-Dong Huang, Siva Sundara Kumar Durairajan

“…Dysfunction in motor protein-mediated neuronal transport mechanisms occurs in several neurodegenerative disorders but remains understudied in AD. …”
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The mitotic spindle is chiral due to torques within microtubule bundles by Maja Novak, Bruno Polak, Juraj Simunić, Zvonimir Boban, Barbara Kuzmić, Andreas W. Thomae, Iva M. Tolić, Nenad Pavin

“…Here, using super-resolution microscopy and computational modelling, the authors find that in addition to forces, torques caused by the microtubule motor protein kinesin-5 induce chirality and curves into the spindle.…”
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A cellular basis for Wolbachia recruitment to the host germline. by Laura R Serbus, William Sullivan

“…Here we report that the wMel Wolbachia strain relies upon a two-step mechanism for its posterior localization in oogenesis. The microtubule motor protein kinesin-1 transports wMel toward the oocyte posterior, then pole plasm mediates wMel anchorage to the posterior cortex. …”
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Lipid-mediated prestin organization in outer hair cell membranes and its implications in sound amplification by Sepehr Dehghani-Ghahnaviyeh, Zhiyu Zhao, Emad Tajkhorshid

“…Prestin, a motor protein, plays a major role in sound amplification. …”
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Roles for CEP170 in cilia function and dynein-2 assembly by Weijman, JF, Vuolo, L, Shak, C, Pugnetti, A, Mukhopadhyay, AG, Hodgson, LR, Heesom, KJ, Roberts, AJ, Stephens, DJ

“…Dynein-2 is a microtubule-motor protein complex and is required for ciliogenesis via its role in facilitating retrograde intraflagellar transport (IFT) from the cilia tip to the cell body. …”

Resolving the role of actoymyosin contractility in cell microrheology. by Christopher M Hale, Sean X Sun, Denis Wirtz

“…Recent work based on reconstituted actin filament networks suggests that nonthermal forces driven by the motor protein myosin II can induce large non-equilibrium fluctuations that dominate the motion of particles in cytoskeletal networks. …”
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How Enzymes Work: A Look through the Perspective of Molecular Viscoelastic Properties by Hao Qu, Giovanni Zocchi

“…We estimate the stall force of the motor protein kinesin from thermodynamic quantities and estimate the maximum rate of enzymes from purely mechanical quantities. …”
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Emerging roles of centrosome cohesion by Hairuo Dang, Elmar Schiebel

“…Alternatively, centrosomes can be kept together by the action of the minus end directed kinesin motor protein KIFC3 that works on interdigitating microtubules organized by both centrosomes and probably by the actin network. …”
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Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders by Dick eJaarsma, Casper eHoogenraad

“…In neurons, the Golgi apparatus is important for the development of axons and dendrites and maintenance of their highly polarized morphology. The motor protein complex cytoplasmic dynein has an important role in Golgi apparatus positioning and function. …”
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Activated T cell trans-endothelial migration relies on myosin-IIA contractility for squeezing the cell nucleus through endothelial cell barriers. by Jordan Jacobelli, Miriam Estin Matthews, Stephanie Chen, Matthew F Krummel

“…T cells can extend protrusions and project a substantial portion of their cytoplasm through the endothelial wall in the absence of MyoIIA. However, this motor protein plays a crucial role in allowing T cells to complete the movement of their relatively rigid nucleus through the endothelial junctions. …”
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Selective retention of dysfunctional mitochondria during asymmetric cell division in yeast. by Xenia Chelius, Veronika Bartosch, Nathalie Rausch, Magdalena Haubner, Jana Schramm, Ralf J Braun, Till Klecker, Benedikt Westermann

“…Together, our data suggest a mechanism in which the combination of blocked fusion and loss of motor protein ensures that damaged mitochondria are retained in the mother cell to ensure rejuvenation of the bud.…”
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A protective mechanism against antibiotic-induced ototoxicity: role of prestin. by Li Yu, Xiao Hua Jiang, Zhen Zhou, Lai Ling Tsang, Mei Kuen Yu, Yiu Wa Chung, Xiao Hu Zhang, Ai Mei Wang, Hao Tang, Hsiao Chang Chan

“…In the present study, we test the possibility that prestin, the motor protein specifically expressed in the basolateral membrane of outer hair cells (OHCs) in the cochlea with electromotility responsible for sound amplification, may be involved in the process of AG-induced apoptosis in OHCs. …”
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Hook2 contributes to aggresome formation by Yu Michelle, Didier Aaron, Hall Branden, Wigley W Christian, Szebenyi Györgyi, Thomas Philip, Krämer Helmut

“…Linker proteins that can associate with the motor protein dynein, organelles, and microtubules are thought to contribute to the active maintenance of the juxtanuclear localization of many membrane bound organelles and aggresomes. …”
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The Aspergillus nidulans kinesin-3 tail is necessary and sufficient to recognize modified microtubules. by Constanze Seidel, Nadine Zekert, Reinhard Fischer

“…This is the first demonstration of how a kinesin-3 motor protein distinguishes among different MT populations in fungal cells, and how specificity determination depends on the tail rather than the motor domain, as has been demonstrated for kinesin 1 in neuronal cells.…”
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