Showing 701 - 720 results of 4,778 for search '"mutagenesis"', query time: 0.17s Refine Results
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    Transposon mutagenesis and genome sequencing identify two novel, tandem genes involved in the colony spreading of Flavobacterium collinsii, isolated from an ayu fish, Plecoglossus altivelis by Yoshio Kondo, Kenichi Ohara, Ryoji Fujii, Yudai Nakai, Chikara Sato, Chikara Sato, Chikara Sato, Chikara Sato, Mariko Naito, Takayuki Tsukuba, Tomoko Kadowaki, Keiko Sato

    Published 2023-02-01
    “…Genomic analysis of F. collinsii GiFuPREF103 revealed the presence of a type IX secretion system and additional genes associated with gliding motility and spreading. Using transposon mutagenesis, we isolated two mutants with altered colony morphology and colony spreading ability; these mutants had transposon insertions in pep25 and lbp26. …”
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    Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle <it>Tribolium castaneum</it>, identifies embryonic lethal mutations and enhancer traps by Klingler Martin, Beeman Richard W, Shippy Teresa D, Wimmer Ernst A, Lorenzen Marcé D, Schinko Johannes, Trauner Jochen, Bucher Gregor, Brown Susan J

    Published 2009-11-01
    “…</p> <p>Results</p> <p>To produce easy-to-maintain insertional mutations and to obtain fluorescent marker lines to aid phenotypic analysis, we undertook a large-scale transposon mutagenesis screen. In this screen, we produced more than 6,500 new <it>piggyBac </it>insertions. …”
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    A Non-Rogue Mutant Line Induced by ENU Mutagenesis in Paramutated Rogue Peas (<i>Pisum sativum</i> L.) Is Still Sensitive to the Rogue Paramutation by Ricardo Pereira, José M. Leitão

    Published 2021-10-01
    “…Here, we report the induction via 1-ethyl-1-nitrosourea (ENU) mutagenesis of a non-rogue revertant mutant in the rogue cv. …”
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    New Insights into the Regulation of Cell-Surface Signaling Activity Acquired from a Mutagenesis Screen of the Pseudomonas putida IutY Sigma/Anti-Sigma Factor by María A. Llamas, Karlijn C. Bastiaansen, Karlijn C. Bastiaansen, Cristina Civantos, Wilbert Bitter

    Published 2017-05-01
    “…We performed a random mutagenesis screen of the unique IutY protein of Pseudomonas putida, a protein that combines a cytosolic σECF domain and a periplasmic anti-sigma factor domain in a single polypeptide. …”
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  12. 712

    Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O6-Methylguanine Methyltransferase, MGMT by Thongararm, Pennapa, Fedeles, Bogdan I., Khumsubdee, Sakunchai, Armijo, Amanda L., Croy, Robert G., Essigmann, John M.

    Published 2020
    “…The DNA repair protein MGMT (O6-methylguanine DNA methyltransferase) protects against environmental mutagenesis by DNA methylating agents and, by removing m6G, limits the therapeutic potential of Temozolomide in cancer therapy. …”
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  13. 713

    Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade. by White, G, McNeill, E, Christou, I, Channon, K, Greaves, D

    Published 2011
    “…To elucidate the residues involved in chemokine neutralization, we performed site-directed mutagenesis of six key amino acids in 35K and expressed the mutant Fc-fusion proteins in vitro. …”
    Journal article
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    A novel mutagenesis strategy identifies distantly spaced amino acid sequences that are required for the phosphorylation of both the oligosaccharides of procathepsin D by N-acetylglucosamine 1-phosphotransferase. by Dustin, M, Baranski, T, Sampath, D, Kornfeld, S

    Published 1995
    “…A novel combinatorial mutagenesis strategy (shuffle mutagenesis) was developed to identify sequences in the propiece and amino lobe of cathepsin D which direct oligosaccharide phosphorylation by UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine 1-phosphotransferase. …”
    Journal article
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    Imbalanced immunobiological reactivity, infection and mutagenesis factors in the hepatobiliary system affected by a natural focal habitat factor — a trematode invasion by <i>Opisthorchis felineus</i> by A. G. Rybka

    Published 2021-12-01
    “…An interaction between decreasing host anti-infective defense due to long-term invasion with Opisthorchis felineus in the hepatobiliary system, duct bile colonization by microflora and revealing the endogenous mutagenesis (carcinogenesis) factor in bile — secondary bile acids — is considered in the article. …”
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