Manganese-enhanced magnetic resonance assessment of changes in hippocampal neural function after the treatment of radiation-induced brain injury with bone marrow mesenchymal stem c... by Zhanhong Liu, Kaina Xu, Shichao Pan, Na Zhang, Dapeng Wang, Ying Chen, Yaru Zhao, Siqi Wang, Jing Li, Xu Tong

“…After BMSCs treatment of RIBI, cognitive dysfunction improved significantly, the expression of hippocampal neurofunctional proteins was increased, the integrity of the hippocampal neural structure was protected, and nerve cell survival was enhanced. The improvement in neurological function was successfully detected by MEMRI, and MEMRI was highly correlated with cognitive function and histological changes. …”
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Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke by Xiaoxue Du, Nashwa Amin, Nashwa Amin, Linhao Xu, Linhao Xu, Benson O. A. Botchway, Benson O. A. Botchway, Bo Zhang, Marong Fang

“…This report conclusively demonstrates that curcumin has neuroprotective properties that inhibit inflammation and prevent nerve cell loss, thereby delaying the progression of ischemic brain damage.…”
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Marine Natural Products, Multitarget Therapy and Repurposed Agents in Alzheimer’s Disease by Márcia Martins, Renata Silva, Madalena M. M. Pinto, Emília Sousa

“…Alzheimer’s disease (AD) is a multifactorial disease characterized by the presence of amyloid plaques, neurofibrillary tangles, and nerve cell death that affects, mainly, older people. …”
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Brain volume increase and neuronal plasticity underly predator-induced morphological defense expression in Daphnia longicephala by A Graeve, I Ioannidou, J Reinhard, D. M. Görl, A Faissner, LC Weiss

“…Our results indicate a structural rewiring of nerve-cell connections upon predator perception and provide important insights into how the nervous system of prey species interprets predator cues and develops cost–benefit optimized defenses.…”
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Association of OPRM1 with addiction: a review on drug, alcohol and smoking addiction in worldwide population by Vanlal Hriatpuii, Hoikhe Priscilla Sema, Chenkual Vankhuma, Mahalaxmi Iyer, Mohana Devi Subramaniam, Krothapalli R. S. Sambasiva Rao, Balachandar Vellingiri, Nachimuthu Senthil Kumar

“…Abstract Background Drugs are chemicals which can disrupt the nerve cell functions of the brain. The present study aims to investigate the addiction related gene (OPRM1) in three types of addiction—drugs, alcohol and smoking. …”
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MicroRNA-1297 suppressed the Akt/GSK3 signaling pathway and stimulated neural apoptosis in an sevoflurane exposure model by Quan Wang, Jingcong Luo, Ruiqiang Sun, Jia Liu

“…Objective Common inhalation anesthetics used for clinical anesthesia (such as sevoflurane) may induce nerve cell apoptosis during central nervous system development. …”
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A Brief History of Simulation Neuroscience by Xue Fan, Henry Markram

“…In this review, we attempt to reconstruct the deep historical paths leading to simulation neuroscience, from the first observations of the nerve cell to modern efforts to digitally reconstruct and simulate the brain. …”
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The semaphorin 3A inhibitor SM-345431 accelerates peripheral nerve regeneration and sensitivity in a murine corneal transplantation model. by Masahiro Omoto, Satoru Yoshida, Hideyuki Miyashita, Tetsuya Kawakita, Kenji Yoshida, Akiyoshi Kishino, Toru Kimura, Shinsuke Shibata, Kazuo Tsubota, Hideyuki Okano, Shigeto Shimmura

“…METHODOLOGY/PRINCIPAL FINDINGS: P0-Cre/Floxed-EGFP mice which express EGFP in peripheral nerves cells were used as recipients of corneal transplantation with syngeneic wild-type mouse cornea donors. …”
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Risk factors of transient ischemic attack: An overview by Supreet Khare

“…One-third of the people with TIA can later have recurrent TIAs and one-third can have a stroke because of permanent nerve cell loss. Having a TIA is a risk factor for eventually having a stroke. …”
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Diffusion tensor imaging of brain abnormalities induced by prenatal exposure to radiation in rodents. by Shigeyoshi Saito, Kazuhiko Sawada, Miwa Hirose, Yuki Mori, Yoshichika Yoshioka, Kenya Murase

“…The DTI color-coded map revealed a dose-dependent reduction in the anisotropic signal (vertical direction), which did not represent reduced numbers of pyramidal cells; rather, it indicated a signal reduction relative to the vertical direction because of low nerve cell density in the entire cortex. We conclude that DTI and histological experiments are useful tools for assessing cortical and hippocampal abnormalities after prenatal exposure to radiation in rats.…”
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A neurochemical map of the developing amphioxus nervous system by Candiani Simona, Moronti Luca, Ramoino Paola, Schubert Michael, Pestarino Mario

“…This map is a first step towards a full characterization of the neurotransmitter signature of previously described nerve cell types in the amphioxus CNS, such as motoneurons and interneurons.…”
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Implantation with SHED sheet induced with homogenate protein of spinal cord promotes functional recovery from spinal cord injury in rats by Sisi Mi, Xue Wang, Jiaxin Gao, Yu Liu, Zhongquan Qi

“…Hp–SHED sheet was implanted into the spinal cord lesion for treating SCI rats with SHED suspensions as a control to investigate the effects on nerve regeneration.Results: Hp–SHED sheet revealed a highly porous three–dimensional inner structure, which facilitates nerve cell attachment and migration. Hp-SHED sheet in vivo restored sensory and motor functions in SCI rats by promoting nerve regeneration, axonal remyelination, and inhibiting glial scarring.Discussion: Hp–SHED sheet maximally mimics the microenvironment of the natural spinal cord and facilitate cell survival and differentiation. …”
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Application of artificial hibernation technology in acute brain injury by Xiaoni Wang, Shulian Chen, Xiaoyu Wang, Zhen Song, Ziqi Wang, Xiaofei Niu, Xiaochu Chen, Xuyi Chen

“…Controlling intracranial pressure, nerve cell regeneration, and microenvironment regulation are the key issues in reducing mortality and disability in acute brain injury. …”
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Growing Neural PC-12 Cell on Crosslinked Silica Aerogels Increases Neurite Extension in the Presence of an Electric Field by Kyle J Lynch, Omar Skalli, Firouzeh Sabri

“…In addition, the physical and chemical properties of the substrate used for nerve-cell regeneration is critical in fostering regeneration. …”
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Modification of Collagen Film via Surface Grafting of Taurine Molecular to Promote Corneal Nerve Repair and Epithelization Process by Yang Liu, Chuanlei Zhang, Yanhui Kong, Huiyu Liu, Jia Guo, Hui Yang, Linhong Deng

“…The research results indicate that the Col-Tau sample has high transmittance and good mechanical properties, and exhibits excellent capacity to promote corneal nerve cell growth and the epithelization process of corneal epithelial cells. …”
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Localization of immunoreactivities for neuropeptides and neurotransmitter-synthesizing enzymes in the pterygopalatine ganglion of the pig by P. Podlasz, K. Wąsowicz, J. Kaleczyc, M. Łakomy, R. Bukowski

“…Tyrosine hydroxylase-positive (TH-positive) neurons were not detected, although in single nerve cell bodies, TH antibody revealed very weak staining which could be attributed to some residual TH immunoreactivity. …”
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The Neuroprotective Effects of Electroacupuncture on Parkinson's Disease and the Underlying Molecular Mechanisms by Qiuqin Han, Peiqing Chen, Xiaorong Chen, Lijuan Wang, Renyan Huang, Wenhui Li, Guobin Liu

“…Besides, the underlying molecular mechanisms of electroacupuncture on PD that contribute to protecting dopaminergic neurons and reducing α-synuclein levels have been illustrated, including ① anti-oxidant stress response, ② anti-neuroinflammatory response, ③ up-regulation of neurotrophic factors and reduction of nerve cell apoptosis, ④ down-regulation of endoplasmic reticulum stress and improvement of mitochondrial function, ⑤ improvement of the function of the ubiquitin-proteasome system, ⑥ anti-excitatory toxicity response, ⑦ activation of autophagy, and ⑧ modulation of gut microbiota. …”
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Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cerebral Ischemia/Reperfusion Injury by Lei Wang, Yan Liu, Xu Zhang, Yingze Ye, Xiaoxing Xiong, Shudi Zhang, Lijuan Gu, Zhihong Jian, Hongfa Wang

“…CIRI-induced apoptosis leads to nerve cell death, which ultimately aggravates neurological deficits in patients. …”
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Piezoresponse, Mechanical, and Electrical Characteristics of Synthetic Spider Silk Nanofibers by Nader Shehata, Ishac Kandas, Ibrahim Hassounah, Patrik Sobolčiak, Igor Krupa, Miroslav Mrlik, Anton Popelka, Jesse Steadman, Randolph Lewis

“…The synthesized nanocomposite can be useful for further biomedical applications, such as nerve cell regrowth and drug delivery.…”
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C-176 loaded Ce DNase nanoparticles synergistically inhibit the cGAS-STING pathway for ischemic stroke treatment by Zhixin Zhu, Haipeng Lu, Lulu Jin, Yong Gao, Zhefeng Qian, Pan Lu, Weijun Tong, Pik Kwan Lo, Zhengwei Mao, Haifei Shi

“…The neuroinflammatory responses following ischemic stroke cause irreversible nerve cell death. Cell free-double strand DNA (dsDNA) segments from ischemic tissue debris are engulfed by microglia and sensed by their cyclic GMP-AMP synthase (cGAS), which triggers robust activation of the innate immune stimulator of interferon genes (STING) pathway and initiate the chronic inflammatory cascade. …”
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