Functional and Molecular Analysis of Proprioceptive Sensory Neuron Excitability in Mice by Jessica F. Madden, Jessica F. Madden, Olivia C. Davis, Kieran A. Boyle, Jacqueline A. Iredale, Jacqueline A. Iredale, Tyler J. Browne, Tyler J. Browne, Robert J. Callister, Robert J. Callister, Douglas W. Smith, Douglas W. Smith, Phillip Jobling, Phillip Jobling, David I. Hughes, Brett A. Graham, Brett A. Graham

“…As the calcium-binding protein parvalbumin (PV) is a neurochemical marker for proprioceptive DRG cells we used a transgenic mouse line expressing green fluorescent protein (GFP) in PV positive DRGs, to study the functional and molecular properties of putative proprioceptive neurons. …”
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Interacciones neuroinmunológicas en el ictus by M.A. Sotomayor-Sobrino, A. Ochoa-Aguilar, L.A. Méndez-Cuesta, C. Gómez-Acevedo

“…Development: According to clinical evidence, a number of neurochemical changes take place after stroke, including energy depletion, increased free radical synthesis, calcium accumulation, neurotransmitter imbalance, excitotoxicity, and, at a later stage, immune system activation leading to inflammation.Immune response has been shown to be a major factor in disease progression. …”
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3,4-Methylenedioxy methamphetamine, synthetic cathinones and psychedelics: From recreational to novel psychotherapeutic drugs by Raúl López-Arnau, Raúl López-Arnau, Jordi Camarasa, Jordi Camarasa, Marcel·lí Carbó, Núria Nadal-Gratacós, Núria Nadal-Gratacós, Pol Puigseslloses, María Espinosa-Velasco, María Espinosa-Velasco, Edurne Urquizu, Elena Escubedo, Elena Escubedo, David Pubill, David Pubill

“…However, these substances, by modulation of certain neurochemical pathways, have been proven to have a beneficial effect on some psychiatric disorders. …”
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Evaluation of different procedure involved in the Transcranial Direct Current Stimulation (tDCS) technique experimental application by Lauren Naomi Spezia Adachi, Carla de Oliveira, Rafael Vercelino, Isabel Cristina de Macedo, Gabriela Laste, Alexandre Silva Quevedo, Vanessa Leal Scarabelot, Wolnei Caumo, Iraci Lucena da Silva Torres

“…As this procedure could involve behavior and neurochemical alterations due to stress induced by restriction (thus, it creates a research bias), we hypothesized that a 30-second electrical stimulus application (sham-tDCS) and the physical restriction used during tDCS treatment might alter nociceptive response in rats. …”
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Altered Grooming Syntax and Amphetamine-Induced Dopamine Release in EAAT3 Overexpressing Mice by Angélica P. Escobar, Angélica P. Escobar, Jonathan Martínez-Pinto, Jonathan Martínez-Pinto, Francisco Silva-Olivares, Francisco Silva-Olivares, Ramón Sotomayor-Zárate, Ramón Sotomayor-Zárate, Pablo R. Moya, Pablo R. Moya

“…The aim of this study was to analyze dopamine transmission both in basal conditions and after an acute challenge of amphetamine, using behavioral, neurochemical, molecular, and cellular approaches. We found that in basal conditions, EAAT3glo/CMKII mice performed more grooming events and that they remained in phase 1 of the grooming chain syntax compared with control littermates. …”
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Evaluation of different procedure involved in the Transcranial Direct Current Stimulation (tDCS) technique experimental application by Lauren Naomi Spezia Adachi, Carla de Oliveira, Rafael Vercelino, Isabel Cristina de Macedo, Gabriela Laste, Alexandre Silva Quevedo, Vanessa Leal Scarabelot, Wolnei Caumo, Iraci Lucena da Silva Torres

“…As this procedure could involve behavior and neurochemical alterations due to stress induced by restriction (thus, it creates a research bias), we hypothesized that a 30-second electrical stimulus application (sham-tDCS) and the physical restriction used during tDCS treatment might alter nociceptive response in rats. …”
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Pharmacological Studies on the Role of 5-HT1A Receptors in Male Sexual Behavior of Wildtype and Serotonin Transporter Knockout Rats by Diana Carolina Esquivel-Franco, Diana Carolina Esquivel-Franco, Diana Carolina Esquivel-Franco, Sietse F. de Boer, Marcel Waldinger, Berend Olivier, Berend Olivier, Berend Olivier, Jocelien D. A. Olivier

“…Serotonin transporter knockout (SERT–/–) rats exhibit enhanced extracellular 5-HT levels and desensitized 5-HT1A receptors. These rats model neurochemical changes underlying chronic SSRI-induced sexual dysfunction. …”
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MAFLD progression contributes to altered thalamus metabolism and brain structure by Saverio Nucera, Stefano Ruga, Antonio Cardamone, Anna Rita Coppoletta, Lorenza Guarnieri, Maria Caterina Zito, Francesca Bosco, Roberta Macrì, Federica Scarano, Miriam Scicchitano, Jessica Maiuolo, Cristina Carresi, Rocco Mollace, Luca Cariati, Giuseppe Mazzarella, Ernesto Palma, Micaela Gliozzi, Vincenzo Musolino, Giuseppe Lucio Cascini, Vincenzo Mollace

“…At the baseline and weeks 4, 8, 20, 28 the thalamic neurochemical profile and total cerebral brain volume were evaluated longitudinally in both diet groups using 1H-MRS. …”
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THREE-DIMENSIONAL RECONSTRUCTION OF THE ANTERIOR OLFACTORY NUCLEUS IN THE HUMAN OLFACTORY BULB AND PEDUNCLE. Reconstrucción tridimiensional del núcleo olfatorio anterior en el bul... by Steven Berendsen, Jocelyne V M Peters, Evelien Huisman, Willie Vörster, Piet Hoogland

“…This is in line with previously published neurochemical properties and the selective early, preclinical degener-ation of these cell clusters in neurodegenerative diseases.…”
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Neuropharmacological studies of antidepressant action on brain dopamine systems by Ainsworth, K, Ainsworth, Kerri

“…</p> <p xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Neurochemical experiments established that repeated administration of fluoxetine, sertraline, desipramine and tranylcypromine increased D₂ (but not D₁) receptor mRNA levels within the nucleus accumbens, most notably in the shell subregion. …”

Clinical Investigation of French Maritime Pine Bark Extract on Attention-Deficit Hyperactivity Disorder as compared to Methylphenidate and Placebo: Part 2: Oxidative Stress and Imm... by Anne-Sophie Weyns, Annelies A.J. Verlaet, Maxim Van Herreweghe, Annelies Breynaert, Erik Fransen, Ingrid De Meester, Emilie Logie, Wim Vanden Berghe, Helene Verhelst, Dirk Van West, Ingrid Van Ingelghem, An I. Jonckheere, Diane Beysen, Sandra Kenis, Els Moens, Aalt P.J. van Roest, Huub F.J. Savelkoul, Tess De Bruyne, Luc Pieters, Berten Ceulemans, Nina Hermans

“…Objectives: To evaluate the effect of French Maritime Pine Bark Extract (PBE; Pycnogenol®) on immune, oxidative stress and neurochemical biomarkers in paediatric Attention-Deficit Hyperactivity Disorder (ADHD) as compared to methylphenidate (MPH) and placebo. …”
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Microglial amyloid beta clearance is driven by PIEZO1 channels by Henna Jäntti, Valeriia Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez-Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Damian Hernández, Alice Pébay, Rosalba Giugno, Paula Korhonen, Rashid Giniatullin, Tarja Malm

“…While the impact of neurochemical pathways on microglia had been broadly studied, mechanical receptors regulating microglial functions remain largely unexplored. …”
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Metal and essential element concentrations during pregnancy and associations with autism spectrum disorder and attention-deficit/hyperactivity disorder in children by Thea S. Skogheim, Kjell Vegard F. Weyde, Stephanie M. Engel, Heidi Aase, Pål Surén, Merete G. Øie, Guido Biele, Ted Reichborn-Kjennerud, Ida H. Caspersen, Mady Hornig, Line S. Haug, Gro D. Villanger

“…As we observed mainly similarities among the metals’ and elements’ impact on ASD and ADHD, it could be that the two disorders share some neurochemical and neurodevelopmental pathways. The results warrant further investigation and replication, as well as studies of combined effects of metals/elements and mechanistic underpinnings.…”
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Distinctive Regulation of Emotional Behaviors and Fear-Related Gene Expression Responses in Two Extended Amygdala Subnuclei With Similar Molecular Profiles by Shuhei Ueda, Shuhei Ueda, Masahito Hosokawa, Masahito Hosokawa, Masahito Hosokawa, Koji Arikawa, Kiyofumi Takahashi, Mao Fujiwara, Manami Kakita, Manami Kakita, Manami Kakita, Taro Fukada, Taro Fukada, Hiroaki Koyama, Shin-ichiro Horigane, Shin-ichiro Horigane, Keiichi Itoi, Masaki Kakeyama, Masaki Kakeyama, Hiroko Matsunaga, Haruko Takeyama, Haruko Takeyama, Haruko Takeyama, Haruko Takeyama, Haruhiko Bito, Sayaka Takemoto-Kimura, Sayaka Takemoto-Kimura, Sayaka Takemoto-Kimura

“…While some studies suggested functional differences between these nuclei, others showed anatomical and neurochemical similarities. Despite their complex subnuclear organization, subnuclei-specific functional impact on behavior and their underlying molecular profiles remain obscure. …”
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The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior by I. Suárez-Pereira, I. Suárez-Pereira, I. García-Domínguez, L. Bravo, M. Santiago, J. García-Revilla, A. M. Espinosa-Oliva, I. M. Alonso-Bellido, C. López-Martín, E. M. Pérez-Villegas, J. A. Armengol, E. Berrocoso, E. Berrocoso, J. L. Venero, R. M. de Pablos, R. Ruiz

“…In this study, we analyze the effects of the elimination of caspase-8 (CASP8) on the development of catecholaminergic neurons using neurochemical, ultrastructural, and behavioral tests. …”
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Prosomeric Hypothalamic Distribution of Tyrosine Hydroxylase Positive Cells in Adolescent Rats by María G. Bilbao, María G. Bilbao, Daniel Garrigos, Daniel Garrigos, Marta Martinez-Morga, Marta Martinez-Morga, Angel Toval, Angel Toval, Angel Toval, Yevheniy Kutsenko, Yevheniy Kutsenko, Rosario Bautista, Rosario Bautista, Alberto Barreda, Alberto Barreda, Bruno Ribeiro Do-Couto, Bruno Ribeiro Do-Couto, Luis Puelles, Luis Puelles, José Luis Ferran, José Luis Ferran

“…Most of the studies on neurochemical mapping, connectivity, and physiology in the hypothalamic region were carried out in rats and under the columnar morphologic paradigm. …”
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Cardiac autonomic control in Rett syndrome: Insights from heart rate variability analysis by Ramona Cordani, Ramona Cordani, Eleonora Tobaldini, Eleonora Tobaldini, Gabriel Dias Rodrigues, Donatella Giambersio, Donatella Giambersio, Marco Veneruso, Marco Veneruso, Lorenzo Chiarella, Nicola Disma, Elisa De Grandis, Elisa De Grandis, Edgar Toschi-Dias, Edgar Toschi-Dias, Ludovico Furlan, Angelica Carandina, Angelica Carandina, Giulia Prato, Lino Nobili, Lino Nobili, Nicola Montano, Nicola Montano

“…In addition, correlations between HRV and genotype and phenotype features or neurochemical changes were investigated. The data reported in this review suggest an important impairment in sympatho-vagal balance, supporting possible future research scenarios, targeting ANS.…”
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Comprehensive management of adults with chronic migraine: Clinical practice guidelines in Mexico by Maria-Karina Vélez-Jiménez, Erwin Chiquete-Anaya, Daniel San Juan Orta, Jorge Villarreal-Careaga, Luis Enrique Amaya-Sánchez, Miguel Ángel Collado-Ortiz, María Luisa Diaz-García, Manuel Gudiño-Castelazo, Juan Hernández-Aguilar, Humberto Juárez-Jiménez, Carolina León-Jiménez, María del Consuelo Loy-Gerala, Alejandro Marfil-Rivera, Marco Antonio Martínez-Gurrola, Adriana Patricia Martínez-Mayorga, Leticia Munive-Báez, Lilia Nuñez-Orozo, Manuel Humberto Ojeda-Chavarría, Luis Roberto Partida-Medina, Juan Carlos Pérez-García, Sandra Quiñones-Aguilar, María Teresa Reyes-Álvarez, Silvia Cristina Rivera-Nava, Bertha Torres-Oliva, Rubén Darío Vargas-García, Rodrigo Vargas-Méndez, Felipe Vega-Boada, Selene Berenice Vega-Gaxiola, Hilda Villegas-Peña, Ildefonso Rodriguez-Leyva

“…Introduction: Migraine is a polygenic multifactorial disorder with a neuronal initiation of a cascade of neurochemical processes leading to incapacitating headaches. …”
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Neuroprotective potential of Cordia dichotoma in Parkinson's syndrome induced by haloperidol: An animal study by Keserla Bhavani, A. Muthukumar, Mansour Almuqbil, Kuntal Das, Yakshitha V., Moneer E. Almadani, Ahmed Alshehri, Adel Alghamdi, Syed Arif Hussain, Bader Hussain Alamer, Ebtesam Abdulrahman Jibreel, Syed Imam Rabbani, Turki Mohammed Alosaimi, Waleed Farah Alharbi, Sultan Mohammed Aldosari, Syed Mohammed Basheeruddin Asdaq

“…Rats exposed to haloperidol were assessed for behavioral, neurochemical, and histopathological parameters. Results: C. dichotoma leaves extract dose-dependently increased behavioral activity and muscle coordination. …”
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Cocaine-Induced Changes in Tonic Dopamine Concentrations Measured Using Multiple-Cyclic Square Wave Voltammetry in vivo by Jason Yuen, Jason Yuen, Abhinav Goyal, Abhinav Goyal, Aaron E. Rusheen, Aaron E. Rusheen, Abbas Z. Kouzani, Michael Berk, Jee Hyun Kim, Susannah J. Tye, Charles D. Blaha, Kevin E. Bennet, Kevin E. Bennet, Dong-Pyo Jang, Kendall H. Lee, Kendall H. Lee, Hojin Shin, Yoonbae Oh, Yoonbae Oh

“…Taken together, M-CSWV has the potential to provide an unprecedented level of physiologic insight into dopamine signaling, both in vitro and in vivo, which will significantly enhance our understanding of neurochemical mechanisms underlying psychiatric conditions.…”
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