Showing 201 - 220 results of 8,186 for search '"neurodegeneration"', query time: 0.10s Refine Results
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    Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes by Ching-On Wong

    Published 2020-07-01
    “…Given the indispensable role of astrocytes in brain metabolic homeostasis, the endosomal-lysosomal processing of these proteins plays a fundamental role in altering the trajectory of neurodegeneration. This review aims at summarizing the mounting evidence that has established the essential role of astrocytic endosomal-lysosomal organelles in the processing of amyloid precursor proteins, Apolipoprotein E (ApoE), tau, alpha synuclein, and huntingtin, which are associated with NDs such as Alzheimer’s, Parkinson’s, and Huntington diseases.…”
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    Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration by Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Juan M Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A Sánchez-Alcázar

    Published 2023-01-01
    Subjects: “…4-hidroxynonenal; ferroptosis; iron; lipid peroxidation; lipofuscin; neurodegeneration; neurodegeneration with brain iron accumulation; oxidative stress; pla2g6-associated neurodegeneration…”
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