DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease by Heling Wang, Sofie Lautrup, Domenica Caponio, Jianying Zhang, Evandro F. Fang

“…Except for WS, a common trait of the aforementioned progerias is neurodegeneration. Evidence from studies using animal models and patient tissues suggests that the associated DNA repair deficiencies lead to depletion of cellular nicotinamide adenine dinucleotide (NAD⁺), resulting in impaired mitophagy, accumulation of damaged mitochondria, metabolic derailment, energy deprivation, and finally leading to neuronal dysfunction and loss. …”
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The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma by Ana I. Ramirez, Ana I. Ramirez, Rosa de Hoz, Rosa de Hoz, Elena Salobrar-Garcia, Elena Salobrar-Garcia, Juan J. Salazar, Juan J. Salazar, Blanca Rojas, Blanca Rojas, Daniel Ajoy, Inés López-Cuenca, Pilar Rojas, Pilar Rojas, Alberto Triviño, Alberto Triviño, José M. Ramírez, José M. Ramírez

“…AD is an age-related neurodegeneration of the CNS characterized by neuronal and synaptic loss in the cerebral cortex, resulting in cognitive deficit and dementia. …”
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Trans-synaptic degeneration as a mechanism of neurodegeneration in multiple sclerosis by Olwen C Murphy, Peter A Calabresi, Shiv Saidha

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Impairment of Neuronal Mitochondrial Quality Control in Prion-Induced Neurodegeneration by Mo-Jong Kim, Hee-Jun Kim, Byungki Jang, Hyun-Ji Kim, Mohd Najib Mostafa, Seok-Joo Park, Yong-Sun Kim, Eun-Kyoung Choi

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Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse by Jie Zhang, Liang Li, Haoliang Huang, Fang Fang, Hannah C Webber, Pei Zhuang, Liang Liu, Roopa Dalal, Peter H Tang, Vinit B Mahajan, Yang Sun, Shaohua Li, Mingchang Zhang, Jeffrey L Goldberg, Yang Hu

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Functions of Plexins/Neuropilins and Their Ligands during Hippocampal Development and Neurodegeneration by Vanessa Gil, José Antonio del Río

“…Here, we will focus on their roles in the hippocampal formation that plays a crucial role in memory and learning as it is a prime target during neurodegeneration.…”
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Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy by Scott C. Vermilyea, Anne Christensen, Joyce Meints, Balvindar Singh, Héctor Martell-Martínez, Md. Razaul Karim, Michael K. Lee

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Editorial: Chronic Inflammation and Neurodegeneration in Retinal Disease, Volume II by Claudio Bucolo, Julie Sanderson, Settimio Rossi

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Role of astrocytes in neuronal energetic production and its relationship with neurodegeneration by Gloria Patricia Cardona Gomez

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Clinical Heterogeneity of Atypical Pantothenate Kinase-Associated Neurodegeneration in Koreans by Jae-Hyeok Lee, Jongkyu Park, Ho-Sung Ryu, Hyeyoung Park, Young Eun Kim, Jin Yong Hong, Sang Ook Nam, Young-Hee Sung, Seung-Hwan Lee, Jee-Young Lee, Myung Jun Lee, Tae-Hyoung Kim, Chul Hyoung Lyoo, Sun Ju Chung, Seong Beom Koh, Phil Hyu Lee, Jin Whan Cho, Mee Young Park, Yun Joong Kim, Young H. Sohn, Beom Seok Jeon, Myung Sik Lee

Subjects: “…Pantothenate kinase-associated neurodegeneration…”
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Cerebrolysin protects against rotenone-induced oxidative stress and neurodegeneration by Abdel-Salam OME, Mohammed NA, Youness ER, Khadrawy YA, Omara EA, Sleem AA

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DIFFERENTIAL COMPARTMENTALIZATION OF MYELOID CELLS DURING HOMEOSTASIS AND IN NEURODEGENERATION IN HUMANS by Camila Fernandez Zapata, Ginevra Giacomello, Eike Spruth, Jinte Middeldorp, Gerardina Gallaccio, Adeline Dehlinger, Claudia Dames, Roland E Van Dijk, Andreas Meisel, Stephan Schlickeiser, Desiree Kunkel, Elly Hol, Friedemann Paul, Maria Parr, Josef Priller, Chotima Böttcher

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Blood biomarkers and neurodegeneration in individuals exposed to repetitive head impacts by Charles Bernick, Guogen Shan, Aaron Ritter, Nicholas J. Ashton, Kaj Blennow, Juan Lantero-Rodriguez, Anniina Snellman, Henrik Zetterberg

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Polyphenols as potential enhancers of stem cell therapy against neurodegeneration by Diana Rodríguez-Vera, Antonio Abad-García, Nancy Vargas-Mendoza, Rodolfo Pinto-Almazán, Eunice D Farfán-García, José A Morales-González, Marvin A Soriano-Ursúa

“…Thus, stem cells exhibit several responses when polyphenols are added to their environment, which could provide us with knowledge for advancing the elucidation of the origin of neurodegeneration. But also, polyphenols are being included in the innovative strategies of novel therapies for treating neurodegenerative diseases as well as metabolic diseases related to neurodegeneration. …”
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Technological advances expand our knowledge of lysosomal dysfunction in neurodegeneration by Chase Chen, Yu Chen, Ellen Sidransky

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Neural Surface Antibodies and Neurodegeneration: Clinical Commonalities and Pathophysiological Relationships by Maria Pia Giannoccaro, Federico Verde, Luana Morelli, Giovanni Rizzo, Fortuna Ricciardiello, Rocco Liguori

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The relationship of topographical memory performance to regional neurodegeneration in Alzheimer’s disease by George ePengas, Guy eWilliams, Julio eAcosta-Cabronero, Tom eAsh, Young eHong, David eIzquierdo-Garcia, Tim eFryer, John eHodges, Peter eNestor

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Oxidative Stress, a Crossroad Between Rare Diseases and Neurodegeneration by Carmen Espinós, Máximo Ibo Galindo, María Adelaida García-Gimeno, José Santiago Ibáñez-Cabellos, Dolores Martínez-Rubio, José María Millán, Regina Rodrigo, Pascual Sanz, Marta Seco-Cervera, Teresa Sevilla, Andrea Tapia, Federico V. Pallardó

“…Oxidative stress plays roles in several pathological processes in the nervous system, such as neurotoxicity, neuroinflammation, ischemic stroke, and neurodegeneration. The concepts of oxidative stress and rare diseases were formulated in the eighties, and since then, the link between them has not stopped growing. …”
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Neuroinflammation as a Key Driver of Secondary Neurodegeneration Following Stroke? by Shannon M. Stuckey, Lin Kooi Ong, Lyndsey E. Collins-Praino, Renée J. Turner

“…Importantly, in these distal regions, termed sites of secondary neurodegeneration (SND), spikes in neuroinflammation may be seen sometime after the initial stroke onset, but prior to the presence of the neuronal tissue damage within these regions. …”
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Regulatory T cells limit age-associated retinal inflammation and neurodegeneration by María Llorián-Salvador, Alerie G. de Fuente, Christopher E. McMurran, Amy Dashwood, James Dooley, Adrian Liston, Rosana Penalva, Yvonne Dombrowski, Alan W. Stitt, Denise C. Fitzgerald

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