Novel therapeutic strategies targeting mitochondria as a gateway in neurodegeneration by Diogo Trigo, José João Vitória, Odete A. B. da Cruz e Silva

Subjects: “…alzheimer’s disease; axon; energy homeostasis; glymphatic system; mitochondria; mitostasis; neurodegeneration; neuroregeneration; parkinson’s disease; therapeutical strategies…”
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Protein Biomarkers for the Diagnosis of Alzheimer’s Disease at Different Stages of Neurodegeneration by Mar Pérez, Félix Hernández, Jesús Avila

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AN ADVANCED IN VITRO TOOL TO STUDY GUT-BRAIN AXIS IN NEURODEGENERATION by Francesca Fanizza, Lucia Boeri, Francesca Negro, Francesca Pugli, Gianluigi Forloni, Carmen Giordano, Diego Albani

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STRUCTURAL AND FUNCTIONAL HETEROGENEITY OF ASTROCYTES IN THE BRAIN: ROLE IN NEURODEGENERATION AND NEUROINFLAMMATION by A. V. Morgun, N. A. Malinovskaya, Yu. K Komleva, O. L. Lopatina, N. V. Kuvacheva, Yu. A. Panina, T. Ye. Taranushenko, Yu. R. Solonchuk, A. B. Salmina

“…Changes at the initial stages of neurodegeneration or in neurodevelopmental disorders are associated with significant alterations in astroglial structural and functional properties, thus suggesting new approaches to therapeutic strategies implementing astroglia-expressing molecules and targets for effective…”
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Epigenetics in glaucoma: a link between histone methylation and neurodegeneration by Wendy W. Liu, Yang Sun

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Epigenetics in glaucoma: a link between histone methylation and neurodegeneration by Wendy W. Liu, Yang Sun

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Post-Ischemic Neurodegeneration of the Hippocampus Resembling Alzheimer’s Disease Proteinopathy by Ryszard Pluta, Sławomir Januszewski, Stanisław J. Czuczwar

“…Thus, the knowledge of new neurodegenerative mechanisms that cause neurodegeneration of the hippocampus after ischemia, resembling Alzheimer’s disease proteinopathy, will provide the most important therapeutic development goals to date.…”
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Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration by Anna Picca, Riccardo Calvani, Hélio José Coelho-Junior, Francesco Landi, Roberto Bernabei, Emanuele Marzetti

“…The exploration of non-canonical pathways involved in mitochondrial quality control and neurodegeneration may unveil novel targets for the development of therapeutic agents. …”
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Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration by Duraisamy Kempuraj, Duraisamy Kempuraj, Ramasamy Thangavel, Ramasamy Thangavel, Govindhasamy P. Selvakumar, Govindhasamy P. Selvakumar, Smita Zaheer, Mohammad E. Ahmed, Sudhanshu P. Raikwar, Sudhanshu P. Raikwar, Haris Zahoor, Daniyal Saeed, Prashant A. Natteru, Shankar Iyer, Shankar Iyer, Asgar Zaheer, Asgar Zaheer

“…We suggest that mast cell-associated inflammatory mediators from systemic inflammation and brain could augment neuroinflammation and neurodegeneration in the brain. This review article addresses the role of some atypical inflammatory mediators that are associated with mast cell inflammation and their activation of glial cells to induce neurodegeneration.…”
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Gut microbiota and derived metabolomic profiling in glaucoma with progressive neurodegeneration by Yinglei Zhang, Yinglei Zhang, Yinglei Zhang, Yinglei Zhang, Xujiao Zhou, Xujiao Zhou, Xujiao Zhou, Xujiao Zhou, Yi Lu, Yi Lu, Yi Lu, Yi Lu

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Calmodulin Binding Domains in Critical Risk Proteins Involved in Neurodegeneration by Danton H. O’Day

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CD47 in the Brain and Neurodegeneration: An Update on the Role in Neuroinflammatory Pathways by Seyed Mohammad Gheibihayat, Ricardo Cabezas, Nikita G. Nikiforov, Tannaz Jamialahmadi, Thomas P. Johnston, Amirhossein Sahebkar

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Proteostasis defects: Medicinal challenges of imperfect aging & neurodegeneration by Prashant Kumar, Akash Choudhary, Sumit Kinger, Yuvraj Anandrao Jagtap, Ankur Rakesh Dubey, Ravi Kumar Gutti, Deepak Chitkara, Anil K. Suresh, Amit Mishra

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Retinal Neurodegeneration: Correlation between Nutraceutical Treatment and Animal Model by Ilaria Piano, Mattia Di Paolo, Francesca Corsi, Eugenia Piragine, Silvia Bisti, Claudia Gargini, Stefano Di Marco

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Novel insights into the mechanism of reactive oxygen species-mediated neurodegeneration by Shuji Wakatsuki, Toshiyuki Araki

“…Evidence provides new insights into the mechanism of reactive oxygen species-mediated neurodegeneration. In this review, we focus specifically on reactive oxygen species-induced neurite degeneration by highlighting a phosphorylation-dependent regulation of the molecular interaction between ZNRF1 and the NADPH oxidase complex.…”
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Genome instability and loss of protein homeostasis: converging paths to neurodegeneration? by Anna Ainslie, Wouter Huiting, Lara Barazzuol, Steven Bergink

Subjects: “…neurodegeneration…”
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Cyclophilin D in Mitochondrial Dysfunction: A Key Player in Neurodegeneration? by Gabriele Coluccino, Valentina Pia Muraca, Alessandra Corazza, Giovanna Lippe

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Small molecule modulators of chromatin remodeling: from neurodevelopment to neurodegeneration by Dongfang Jiang, Tingting Li, Caixia Guo, Tie-Shan Tang, Hongmei Liu

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Disrupted axon-glia communication leads to neurodegeneration in metabolic diseases by Stacey A. Sakowski, Masha G. Savelieff, Eva L. Feldman

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Cytochrome P450 Metabolism of Polyunsaturated Fatty Acids and Neurodegeneration by Morteza Sarparast, Devon Dattmore, Jamie Alan, Kin Sing Stephen Lee

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