Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical and Translational Neuropsychiatry by Simone Battaglia, Alessio Avenanti, László Vécsei, Masaru Tanaka

“…Neurodegeneration poses a significant challenge for the fields of neuroscience and medicine, as it is the underlying cause of the development and advancement of numerous neurodegenerative and psychiatric disorders [...]…”
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Editorial of Special Issue ‘Dissecting Neurological and Neuropsychiatric Diseases: Neurodegeneration and Neuroprotection’ by Masaru Tanaka, László Vécsei

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Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS by Francesca Navone, Paola Genevini, Nica Borgese

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DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia by Yi-Chinn Weng, Yu-Ting Huang, I-Chen Chiang, Huai-Chia Chuang, Tsong-Hai Lee, Tse-Hua Tan, Wen-Hai Chou

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P2Y1 Receptor as a Catalyst of Brain Neurodegeneration by Ricardo J. Rodrigues, Ana S. Figueira, Joana M. Marques

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NEW ROLES FOR FC RECEPTORS IN NEURODEGENERATION-THE IMPACT ON IMMUNOTHERAPY FOR ALZHEIMER’S DISEASE by James P. Fuller, Jeffrey B. Stavenhagen, Jessica L. Teeling

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Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer's Disease by Xi-Lin Wu, Juan Piña-Crespo, Yun-Wu Zhang, Xiao-Chun Chen, Hua-Xi Xu

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Microglial ion channels: Key players in non-cell autonomous neurodegeneration by Souvarish Sarkar

“…Microglial activation, leading to induction of pro-inflammatory factors, like Interleukin 1-β (IL-1β), Tumor necrosis factor-α (TNFα), nitrites, and others, have been shown to induce neurodegeneration. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce the risk of developing PD, but the mechanism underlying the microglial activation is still under active research. …”
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Roles of Voltage-Dependent Sodium Channels in Neuronal Development, Pain, and Neurodegeneration by Akihiko Wada

“…Sodium channelopathies causing pain (e.g., allodynia) and neurodegeneration (e.g., multiple sclerosis) derive from 1) electrophysiological disturbances by insults (e.g., ischemia /hypoxia, toxins, and antibodies); 2) loss-of-physiological function or gain-of-pathological function of mutant sodium channel proteins; 3) spatiotemporal inappropriate expression of normal sodium channel proteins; or 4) de-repressed expression of otherwise silent sodium channel genes. …”
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Power Failure of Mitochondria and Oxidative Stress in Neurodegeneration and Its Computational Models by JunHyuk Woo, Hyesun Cho, YunHee Seol, Soon Ho Kim, Chanhyeok Park, Ali Yousefian-Jazi, Seung Jae Hyeon, Junghee Lee, Hoon Ryu

“…In addition, we discuss state-of-the-art computational models of mitochondrial functions in relation to oxidative stress and neurodegeneration. Together, a better understanding of brain disease-specific mitochondrial dysfunction and oxidative stress can pave the way to developing antioxidant therapeutic strategies to ameliorate neuronal activity and prevent neurodegeneration.…”
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The Bidirectional Relationship between Sleep and Neurodegeneration: Actionability to Improve Brain Health by Abubaker Ibrahim, Birgit Högl, Ambra Stefani

“…Changes in sleep and circadian rhythms are present not only in overt neurodegenerative diseases but also in their early, prodromal, and preclinical phases, supporting that they precede (and contribute to) the development of neurodegeneration. This narrative review provides a brief overview of sleep and circadian rhythm disruption in neurodegeneration, highlights the bidirectional relationship between sleep changes and neurodegeneration, and addresses future perspectives, in particular, whether sleep changes are able to predict neurodegeneration and the potential sleep actionability to prevent or modulate the development of neurodegenerative diseases.…”
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Pterostilbene fluorescent probes as potential tools for targeting neurodegeneration in biological applications by Lidia Ciccone, Susanna Nencetti, Maria Marino, Chiara Battocchio, Giovanna Iucci, Iole Venditti, Martina Marsotto, Emiliano Montalesi, Simone Socci, Beatrice Bargagna, Elisabetta Orlandini

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Morphological Heterogeneity of the Endoplasmic Reticulum within Neurons and Its Implications in Neurodegeneration by Sreesha Sree, Ilmari Parkkinen, Anna Their, Mikko Airavaara, Eija Jokitalo

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Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson’s Disease by Yashumati Ratan, Aishwarya Rajput, Ashutosh Pareek, Aaushi Pareek, Vivek Jain, Sonia Sonia, Zeba Farooqui, Ranjeet Kaur, Gurjit Singh

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Damage to the Locus Coeruleus Alters the Expression of Key Proteins in Limbic Neurodegeneration by Francesca Biagioni, Michela Ferrucci, Gloria Lazzeri, Mariarosaria Scioli, Alessandro Frati, Stefano Puglisi-Allegra, Francesco Fornai

“…The present data provide further evidence to understand why a loss of LC-NE axons may foster limbic neurodegeneration in AD and limbic engagement during PD.…”
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Modulation of LPS-Induced Neurodegeneration by Intestinal Helminth Infection in Ageing Mice by Natalia Jermakow, Weronika Skarżyńska, Katarzyna Lewandowska, Ewelina Kiernozek, Katarzyna Goździk, Anna Mietelska-Porowska, Nadzieja Drela, Urszula Wojda, Maria Doligalska

“…Here, intraperitoneal LPS-induced systemic inflammation resulting in brain neurodegeneration was enhanced by prolonged <i>Heligmosomoides polygyrus</i> infection in C57BL/6 mice. …”
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String/Cdc25 phosphatase is a suppressor of Tau-associated neurodegeneration by Andreia C. Oliveira, Madalena Santos, Mafalda Pinho, Carla S. Lopes

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Neurodegeneration with brain iron accumulation: a differential diagnosis of cerebral palsy by Alana Ferreira de Andrade, Grace Kelly dos Santos Guimarães, João Ferreira da Silva, Bruno Manuel Moura de Sousa, Marcos Manoel Honorato, Renata Maria de Carvalho Cremaschi, Fernando Morgadinho Santos Coelho

Subjects: “…Neurodegeneration with brain iron accumulation 2A…”
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Sex differences in CSF biomarkers for neurodegeneration and blood‐brain barrier integrity by Tobias Skillbäck, Kaj Blennow, Henrik Zetterberg, Sara Shams, Alejandra Machado, Joana Pereira, Olof Lindberg, Michelle M. Mielke, Anna Zettergren, Lina Ryden, Eric Westman, Lars‐Olof Wahlund, Ingmar Skoog, Silke Kern

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Neurofilament Light Chain in Aqueous Humor as a Marker of Neurodegeneration in Glaucoma by Lin JB, Pitts KM, El Helwe H, Neeson C, Hall NE, Falah H, Schultz SA, Wang SL, Lo K, Song C, Margeta MA, Solá-Del Valle D

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