Showing 441 - 460 results of 8,186 for search '"neurodegeneration"', query time: 0.13s Refine Results
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    The Emerging Role of the RNA-Binding Protein SFPQ in Neuronal Function and Neurodegeneration by Yee Wa Lim, Dylan James, Jie Huang, Mihwa Lee

    Published 2020-09-01
    “…One of the emerging RBPs implicated in neuronal function and neurodegeneration is splicing factor proline- and glutamine-rich (SFPQ). …”
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    RETRACTED ARTICLE: Pericyte loss influences Alzheimer-like neurodegeneration in mice by Abhay P. Sagare, Robert D. Bell, Zhen Zhao, Qingyi Ma, Ethan A. Winkler, Anita Ramanathan, Berislav V. Zlokovic

    Published 2013-12-01
    “…Whether pericyte degeneration can influence AD-like neurodegeneration and contribute to disease pathogenesis remains, however, unknown. …”
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    254 Markers of Neurodegeneration Associate with Worse Performance of Complex Daily Tasks by Audrey A. Keleman, Rebecca M. Bollinger, Beau M. Ances, Susan L. Stark

    Published 2022-04-01
    “…DISCUSSION/SIGNIFICANCE: This study suggests that worse performance of complex daily tasks may be associated with markers of neurodegeneration. These findings could lead to a better understanding of functional changes that may occur during the preclinical stage of AD.…”
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    Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging by Ming-Hui Yang, Yi-Ming Arthur Chen, Shan-Chen Tu, Pei-Ling Chi, Kuo-Pin Chuang, Chin-Chuan Chang, Chiang-Hsuan Lee, Yi-Ling Chen, Che-Hsin Lee, Cheng-Hui Yuan, Yu-Chang Tyan

    Published 2021-03-01
    “…The GnRH pathway could provide additional information on the mechanism of aging and non-aging related neurodegeneration, and these protein markers may be served in developing future therapeutic treatments to ameliorate aging and prevent diseases.…”
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    Virtual screening of flavonoids as potential RIPK1 inhibitors for neurodegeneration therapy by Asim Kumar Bepari, Swakkhar Shatabda, Hasan Mahmud Reza

    Published 2024-01-01
    “…Future in vitro and in vivo studies with these ligands could offer new hope for developing effective therapeutics and improving the quality of life for individuals affected by neurodegeneration.…”
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    Deamidation-related blood biomarkers show promise for early diagnostics of neurodegeneration by Jijing Wang, Ya-Ru Zhang, Xue-Ning Shen, Jinming Han, Mei Cui, Lan Tan, Qiang Dong, Roman A. Zubarev, Jin-Tai Yu

    Published 2022-12-01
    “…Conclusion We demonstrated the diagnostic capacity of deamidation-related biomarkers in predicting NDDs at the early stage of disease, and the biomarker levels significantly correlated with cognitive decline, strongly supporting the role of deamidation in triggering neurodegeneration and early stages of disease development. …”
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    Association of CSF and PET markers of neurodegeneration with electroclinical progression in Lafora disease by Giuseppe d'Orsi, Andrea Farolfi, Lorenzo Muccioli, Orazio Palumbo, Pietro Palumbo, Sergio Modoni, Vincenzo Allegri, Valentina Garibotto, Maria Teresa Di Claudio, Ester Di Muro, Mario Benvenuto, Francesca Bisulli, Francesca Bisulli, Massimo Carella

    Published 2023-06-01
    “…PurposeTo evaluate the electro-clinical features in association with laboratory and instrumental correlates of neurodegeneration to detect the progression of Lafora disease (LD).MethodsWe investigated the electro-clinical longitudinal data and CSF Aβ42, p-tau181 and t-tauAg, amyloid, and 18F-FDG PET of five unrelated LD families.ResultsThree progressive electro-clinical stages were identified. …”
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