New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases by Marian Hruska-Plochan, Bei Li, Diego Kyburz, Jan Krützfeldt, Ulf Landmesser, Adriano Aguzzi, Magdalini Polymenidou

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Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease by Fumiaki Nagashima, Yusuke Miyazaki, Eiki Kanemaru, Mariko Ezaka, Hiroaki Hara, Kei Sugiura, Sophie L. Boerboom, Katrina F. Ostrom, Wanlin Jiang, Donald B. Bloch, Fumito Ichinose, Eizo Marutani

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Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration. by Conlan Kreher, Jacob Favret, Nadav I Weinstock, Malabika Maulik, Xinying Hong, Michael H Gelb, Lawrence Wrabetz, M Laura Feltri, Daesung Shin

“…In Krabbe disease, the brunt of demyelination and neurodegeneration is believed to result from the dysfunction of myelinating glia. …”
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Does Retinal Neurodegeneration Seen in Diabetic Patients Begin in the Insulin Resistance Stage? by Sedat Arıkan, İsmail Erşan, Mustafa Eroğlu, Mehmet Yılmaz, Hasan Ali Tufan, Baran Gencer, Selçuk Kara, Mehmet Aşık

“…Objectives: To investigate whether retinal neurodegeneration and impairment in contrast sensitivity (CS), which have been demonstrated to begin in diabetic patients before the presence of signs of diabetic retinal vasculopathy, also occur in the stage of insulin resistance. …”
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EYE-503: A Novel Retinoic Acid Drug for Treating Retinal Neurodegeneration by Sha Liu, Yuke Ji, Huan Li, Ling Ren, Junya Zhu, Tianjing Yang, Xiumiao Li, Jin Yao, Xin Cao, Biao Yan

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Assessing Cannabidiol as a Therapeutic Agent for Preventing and Alleviating Alzheimer’s Disease Neurodegeneration by Long Chen, Yuan Sun, Jinran Li, Sai Liu, Hancheng Ding, Guangji Wang, Xinuo Li

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The Protective Role of Microglial PPARα in Diabetic Retinal Neurodegeneration and Neurovascular Dysfunction by Tian Yuan, Lijie Dong, Elizabeth A. Pearsall, Kelu Zhou, Rui Cheng, Jian-Xing Ma

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Heads Up! Interlinked Amyloidogenic and Axonal Transport Pathways in Concussion-Induced Neurodegeneration by Angels Almenar-Queralt, Rodrigo dos Santos Chaves, Ester J. Kwon, Sameer B Shah

“…In this commentary, we summarize recent findings in human neurons derived from induced pluripotent stem cells, detailing early neuronal events following mild injury that may seed future neurodegeneration. In particular, we discuss interlinked relationships between mTBI and several biological pathways hypothesized to underlie AD progression, including amyloidogenic cleavage of amyloid precursor protein (APP), impairment of axonal transport, and the development of APP-associated axonal swellings. …”
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Editorial: Central nervous system acting drugs-molecular mechanisms of neuroprotection and neurodegeneration by Nesrine S. El Sayed, Riham Salah El Dine, Barbara Budzyńska, Anna Boguszewska-Czubara, Jolanta Kotlińska

Subjects: “…neurodegeneration…”
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Systematic Review of the Therapeutic Role of Apoptotic Inhibitors in Neurodegeneration and Their Potential Use in Schizophrenia by Constanza Morén, Nina Treder, Albert Martínez-Pinteño, Natàlia Rodríguez, Néstor Arbelo, Santiago Madero, Marta Gómez, Sergi Mas, Patricia Gassó, Eduard Parellada

“…Despite both the apoptotic-hallmarks of SZ and the widespread use of anti-apoptotic targets in neurodegeneration, there is a strikingly scarce number of studies investigating anti-apoptotic approaches in SZ. …”
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P256: Characterization of childhood neurodegeneration and associated ataxia in UBTF-related disorder* by Amanda Nagy, Anna Luddy, Francine Molay, Lizbeth De La Rosa Abreu, Catherine Becker, Anoopum Gupta, Florian Eichler

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Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration. by Marie Y Davis, Kien Trinh, Ruth E Thomas, Selina Yu, Alexandre A Germanos, Brittany N Whitley, Sergio Pablo Sardi, Thomas J Montine, Leo J Pallanck

“…Homozygous dGBA1b mutants exhibit shortened lifespan, locomotor and memory deficits, neurodegeneration, and dramatically increased accumulation of ubiquitinated protein aggregates that are normally degraded through an autophagic mechanism. …”
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Strategies to treat neurodegeneration in neuronal ceroid lipofuscinosis: a view onto the retina by Udo Bartsch

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Downregulation of the Astroglial Connexin Expression and Neurodegeneration after Pilocarpine-Induced Status Epilepticus by Anna Andrioli, Paolo Francesco Fabene, Giuseppa Mudò, Vincenza Barresi, Valentina Di Liberto, Monica Frinchi, Marina Bentivoglio, Daniele Filippo Condorelli

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Disease phenotypic screening in neuron-glia cocultures identifies blockers of inflammatory neurodegeneration by Timothy J.Y. Birkle, Henriette M.G. Willems, John Skidmore, Guy C. Brown

“…Here, we perform compound screening using primary neuron-glia cultures to model inflammatory neurodegeneration, live-cell stains, and automated classification of neurons, astrocytes or microglia using open-source software. …”
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Targetable Pathways for Alleviating Mitochondrial Dysfunction in Neurodegeneration of Metabolic and Non-Metabolic Diseases by Lauren Elizabeth Millichap, Elisabetta Damiani, Luca Tiano, Iain P. Hargreaves

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Identification of target genes in neuroinflammation and neurodegeneration after traumatic brain injury in rats by Jianwei Zhao, Chen Xu, Heli Cao, Lin Zhang, Xuyang Wang, Shiwen Chen

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Editorial: Estrogen effects on fertility and neurodegeneration – classical versus non-classical actions by Zsuzsanna Nagy, Allan Herbison, Andrea Kwakowsky, Gergely Kovacs, Klaudia Barabas

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Relationship between brainstem neurodegeneration and clinical impairment in traumatic spinal cord injury by Patrick Grabher, Claudia Blaiotta, John Ashburner, Patrick Freund

“…Objective: To quantify neurodegeneration and its relation to clinical impairment in major brainstem pathways and nuclei in traumatic SCI. …”
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CSF protein ratios with enhanced potential to reflect Alzheimer’s disease pathology and neurodegeneration by Sára Mravinacová, Vilma Alanko, Sofia Bergström, Claire Bridel, Yolande Pijnenburg, Göran Hagman, Miia Kivipelto, Charlotte Teunissen, Peter Nilsson, Anna Matton, Anna Månberg

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