Source space connectomics of neurodegeneration: One-metric approach does not fit all by Pavel Prado, Sebastian Moguilner, Jhony A. Mejía, Agustín Sainz-Ballesteros, Mónica Otero, Agustina Birba, Hernando Santamaria-Garcia, Agustina Legaz, Sol Fittipaldi, Josephine Cruzat, Enzo Tagliazucchi, Mario Parra, Rubén Herzog, Agustín Ibáñez

“…These joint analyses reveal patterns of brain functional interdependence that are overlooked with single metrics approaches, contributing to a more reliable and interpretable description of atypical functional connectivity in neurodegeneration.…”
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The Role of Alpha-Synuclein Autoantibodies in the Induction of Brain Inflammation and Neurodegeneration in Aged Humans by Manoj Kumar Pandey, Manoj Kumar Pandey

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Nipecotic Acid Derivatives as Potent Agents against Neurodegeneration: A Preliminary Study by Georgios Papagiouvannis, Panagiotis Theodosis-Nobelos, Eleni A. Rekka

“…Acetylcholinesterase inhibitors are the main therapeutic agents against AD, whereas oxidative stress and inflammation have been found to be of great significance for the development and progression of neurodegeneration. In this work, ethyl nipecotate (ethyl-piperidine-3-carboxylate), a heterocyclic carboxylic acid derivative, which acts as a GABA reuptake inhibitor and has been used in research for diseases involving GABAergic neurotransmission dysfunction, was amidated with various carboxylic acids bearing antioxidant and/or anti-inflammatory properties (e.g., ferulic acid, sinapic acid, butylated hydroxycinnamic acid). …”
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Oxidative Stress-Induced Neurodegeneration and Antioxidative Strategies: Current Stage and Future Perspectives by Ana-Maria Buga, Carmen-Nicoleta Oancea

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Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum by Rashmi Gamage, Ilaria Rossetti, Garry Niedermayer, Gerald Münch, Yossi Buskila, Erika Gyengesi

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Effects of Enteric Environmental Modification by Coffee Components on Neurodegeneration in Rotenone-Treated Mice by Ikuko Miyazaki, Nami Isooka, Kouichi Wada, Ryo Kikuoka, Yoshihisa Kitamura, Masato Asanuma

“…Administrations of CA or CGA prevented rotenone-induced neurodegeneration of both nigral dopaminergic and intestinal enteric neurons. …”
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Simulation of neuroplasticity in a CNN-based in-silico model of neurodegeneration of the visual system by Jasmine A. Moore, Jasmine A. Moore, Jasmine A. Moore, Matthias Wilms, Matthias Wilms, Matthias Wilms, Alejandro Gutierrez, Alejandro Gutierrez, Alejandro Gutierrez, Zahinoor Ismail, Zahinoor Ismail, Kayson Fakhar, Fatemeh Hadaeghi, Claus C. Hilgetag, Claus C. Hilgetag, Nils D. Forkert, Nils D. Forkert, Nils D. Forkert

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Neurodegeneration Biomarkers in Adult Spinal Muscular Atrophy (SMA) Patients Treated with Nusinersen by Pol Andrés-Benito, Juan Francisco Vázquez-Costa, Nancy Carolina Ñungo Garzón, María J. Colomina, Carla Marco, Laura González, Cristina Terrafeta, Raúl Domínguez, Isidro Ferrer, Mónica Povedano

“…A reduction in sAPPβ levels was found after nusinersen treatment, but these levels did not correlate with clinical outcomes. Other neurodegeneration biomarkers (NF-L, pNF-H, total tau, YKL-40, Aβ40, and Aβ42) were not found consistently changed with nusinersen treatment. …”
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Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes by Sulev Koks, Abigail L. Pfaff, Vivien J. Bubb, John P. Quinn

“…APOE e4 and MAPT H1/H2 haplotypic variants are associated with the expression of several genes related to the neurodegeneration.…”
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Secondary neurodegeneration following Stroke: what can blood biomarkers tell us? by Stefano Brunelli, Emilia Giannella, Mirko Bizzaglia, Domenico De Angelis, Giulia Maria Sancesario

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Lipids: Key Players That Modulate α-Synuclein Toxicity and Neurodegeneration in Parkinson’s Disease by Akio Mori, Yuzuru Imai, Nobutaka Hattori

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The Multifaceted Role of Cofilin in Neurodegeneration and Stroke: Insights into Pathogenesis and Targeting as a Therapy by Faheem Shehjar, Daniyah A. Almarghalani, Reetika Mahajan, Syed A.-M. Hasan, Zahoor A. Shah

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Collagen in the central nervous system: contributions to neurodegeneration and promise as a therapeutic target by Lauren K. Wareham, Robert O. Baratta, Brian J. Del Buono, Eric Schlumpf, David J. Calkins

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Histological Protection by Donepezil Against Neurodegeneration Induced by Ischemia–Reperfusion in the Rat Retina by Kenji Sakamoto, Kayo Ohki, Maki Saito, Tsutomu Nakahara, Kunio Ishii

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Mitochondrial Dysfunction, Oxidative Stress and Neuroinflammation in Neurodegeneration with Brain Iron Accumulation (NBIA) by Isabel Hinarejos, Candela Machuca, Paula Sancho, Carmen Espinós

“…The syndromes of neurodegeneration with brain iron accumulation (NBIA) encompass a group of invalidating and progressive rare diseases that share the abnormal accumulation of iron in the basal ganglia. …”
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The Contribution of Non-Neuronal Cells in Neurodegeneration: From Molecular Pathogenesis to Therapeutic Challenges by Nadia D’Ambrosi, Mauro Cozzolino, Savina Apolloni

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Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease by Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M. Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M. Hughes, Marc Suárez-Calvet, Thomas K. Karikari, Tormod Fladby, Kaj Blennow

“…Abstract Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). …”
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Interaction of microglia and T cells: a deadly duo behind Tau-mediated neurodegeneration by Bilge Askin, Susanne Wegmann

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Neurobehavioral Testing as Cognitive Function Evaluation tool in Experimentally Induced Neurodegeneration in Mice by Yulia A. Panina, Olga L. Lopatina, Angelina I. Mosyagina, Yulia K. Komleva, Andrey V. Morgun, Yana V. Gorina, Elena D. Hilazheva

Subjects: “…neurodegeneration…”
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Aggregation of TDP-43 fragments triggers cellular aberrant function: implication in neurodegeneration by Che Meixia, Jiang Leilei, Zhou Chenjie, Jiang Yajun, Hu Hongyu

“…Molecular Neurodegeneration…”
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