The SleepFit Tablet Application for Home-Based Clinical Data Collection in Parkinson Disease: User-Centric Development and Usability Study by Mascheroni, Alessandro, Choe, Eun Kyoung, Luo, Yuhan, Marazza, Michele, Ferlito, Clara, Caverzasio, Serena, Mezzanotte, Francesco, Kaelin-Lang, Alain, Faraci, Francesca, Puiatti, Alessandro, Ratti, Pietro Luca

“…BackgroundParkinson disease (PD) is a common, multifaceted neurodegenerative disorder profoundly impacting patients' autonomy and quality of life. …”
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Asiaticoside Attenuates Cell Growth Inhibition and Apoptosis Induced by Aβ1-42 via Inhibiting the TLR4/NF-κB Signaling Pathway in Human Brain Microvascular Endothelial Cells by Daqiang Song, Xian Jiang, Yiliu Liu, Yuhong Sun, Shousong Cao, Zhuo Zhang

“…Alzheimer’s disease (AD) is a very common progressive neurodegenerative disorder with the highest incidence in the world. …”
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A Systematic Review of Transcriptional Dysregulation in Huntington’s Disease Studied by RNA Sequencing by Bimala Malla, Xuanzong Guo, Gökçe Senger, Zoi Chasapopoulou, Ferah Yildirim

“…Huntington’s disease (HD) is a chronic neurodegenerative disorder caused by an expansion of polyglutamine repeats in exon 1 of the Huntingtin gene. …”
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Molecular characterisation of autophagy deficits in a LRRK2-BAC transgenic rat model of Parkinson’s disease by Wallings, R

“…<p>Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. PD is characterised by the preferential loss of dopaminergic neurons in the Substantia Nigra pars compacta in the midbrain accompanied by progressive motor dysfunction. …”

Discovering genetic modifiers in Niemann-Pick Disease Type C by Rodriguez-Gil, J

“…<p>Niemann-Pick Disease, Type C (NPC) is a rare, fatal neurodegenerative disorder characterized by lysosomal accumulation of unesterified cholesterol and sphingolipids. …”

Circulating Small Extracellular Vesicle-Derived miR-342-5p Ameliorates Beta-Amyloid Formation via Targeting Beta-site APP Cleaving Enzyme 1 in Alzheimer’s Disease by Zhiwu Dong, Hongjun Gu, Qiang Guo, Xianglu Liu, Feifei Li, Huiling Liu, Li Sun, Huimin Ma, Kewen Zhao

“…Alzheimer’s disease (AD) is a common neurodegenerative disorder with progressive cognitive impairment in the elderly. …”
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New transgenic models of Parkinson's disease using genome editing technology by J.A. Cota-Coronado, S. Sandoval-Ávila, Y.P. Gaytan-Dávila, N.F. Diaz, B. Vega-Ruiz, E. Padilla-Camberos, N.E. Díaz-Martínez

“…Introduction: Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is characterised by selective loss of dopaminergic neurons in the substantia nigra pars compacta, which results in dopamine depletion, leading to a number of motor and non-motor symptoms. …”
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Neuroprotective effect of naringin against cerebellar changes in Alzheimer’s disease through modulation of autophagy, oxidative stress and tau expression: An experimental study by Hend M. Hassan, Mohamed R. Elnagar, Mohamed R. Elnagar, Eman Abdelrazik, Mohamed R. Mahdi, Eman Hamza, Eman Hamza, Eman M. Elattar, Eman Mohamed ElNashar, Eman Mohamed ElNashar, Mansour Abdullah Alghamdi, Mansour Abdullah Alghamdi, Zainah Al-Qahtani, Khulood Mohammed Al-Khater, Rashid A. Aldahhan, Mamdouh ELdesoqui, Mamdouh ELdesoqui

“…Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by gradual cognitive decline. …”
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Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with delayed... by Lautaro Francisco Belfiori, Alfredo Dueñas Rey, Alfredo Dueñas Rey, Alfredo Dueñas Rey, Dorottya Mária Ralbovszki, Itzia Jimenez-Ferrer, Filip Fredlund, Sagar Shivayogi Balikai, Dag Ahrén, Kajsa Atterling Brolin, Maria Swanberg

“…IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder, increasing both in terms of prevalence and incidence. …”
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Rare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort by Stefanie Krüger, Florian Battke, Andrea Sprecher, Marita Munz, Marita Munz, Matthis Synofzik, Matthis Synofzik, Ludger Schöls, Ludger Schöls, Thomas Gasser, Thomas Gasser, Torsten Grehl, Johannes Prudlo, Johannes Prudlo, Saskia Biskup, Saskia Biskup

“…Amyotrophic lateral sclerosis (ALS) is a progressive fatal multisystemic neurodegenerative disorder caused by preferential degeneration of upper and lower motor neurons. …”
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Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson’s Disease Targeting Neuroinflammation by Chiung-Mei Chen, Chien-Yu Yen, Wan-Ling Chen, Chih-Hsin Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen

“…Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons and the presence of α-synuclein-containing Lewy bodies. …”
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Quantifying Neurodegenerative Progression With DeepSymNet, an End-to-End Data-Driven Approach by Danilo Pena, Danilo Pena, Arko Barman, Arko Barman, Jessika Suescun, Xiaoqian Jiang, Mya C. Schiess, Luca Giancardo, Luca Giancardo, the Alzheimer's Disease Neuroimaging Initiative

“…Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide and is one of the leading sources of morbidity and mortality in the aging population. …”
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Motor Evoked Potentials in Hereditary Spastic Paraplegia—A Systematic Review by Sue-Faye Siow, Sue-Faye Siow, Sue-Faye Siow, Ruaridh Cameron Smail, Ruaridh Cameron Smail, Karl Ng, Karl Ng, Karl Ng, Kishore R. Kumar, Kishore R. Kumar, Kishore R. Kumar, Kishore R. Kumar, Kishore R. Kumar, Carolyn M. Sue, Carolyn M. Sue, Carolyn M. Sue, Carolyn M. Sue

“…Background: Hereditary Spastic Paraplegia (HSP) is a slowly progressive neurodegenerative disorder with no disease modifying treatment. …”
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Unraveling rare form of adult-onset NIID by characteristic brain MRI features: A single-center retrospective review by Fan Li, Qi Wang, Ying Zhu, Jiangxi Xiao, Muliang Gu, Jiaxi Yu, Jianwen Deng, Jianwen Deng, Wei Sun, Wei Sun, Zhaoxia Wang, Zhaoxia Wang

“…Adult-onset neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disorder with high clinical heterogeneity. …”
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Presymptomatic treatment of classic late-infantile neuronal ceroid lipofuscinosis with cerliponase alfa by J. Schaefers, L. J. van der Giessen, C. Klees, E. H. Jacobs, S. Sieverdink, M. H. G. Dremmen, J. K. H. Spoor, A. T. van der Ploeg, J. M. P. van den Hout, H. H. Huidekoper

“…Abstract Background Neuronal ceroid lipofuscinosis type 2 (CLN2 disease) is a rare rapidly progressive neurodegenerative disorder, resulting in early death. Intracerebroventricular enzyme replacement therapy (ERT) with cerliponase alfa is now available and has shown to delay disease progression in symptomatic patients. …”
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Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus by Chen Diling, Yong Tianqiao, Yang Jian, Zheng Chaoqun, Zheng Chaoqun, Shuai Ou, Xie Yizhen

“…Alzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting approximately more than 5% of the population worldwide over the age 65, annually. …”
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A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD by Rustam Esanov, Gabriela Toro Cabrera, Nadja S. Andrade, Tania F. Gendron, Robert H. Brown, Michael Benatar, Claes Wahlestedt, Christian Mueller, Zane Zeier

“…Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a fatal and progressive neurodegenerative disorder with identified genetic causes representing a significant minority of all cases. …”
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Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins by Jens Mayer, Christian Harz, Laura Sanchez, Gavin C. Pereira, Esther Maldener, Sara R. Heras, Lyle W. Ostrow, John Ravits, Ranjan Batra, Eckart Meese, Jose Luis García-Pérez, John L. Goodier

“…Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. About 90% of ALS cases are without a known genetic cause. …”
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HSD10 mitochondrial disease: p.Leu122Val variant, mild clinical phenotype, and founder effect in French‐Canadian patients from Quebec by Paula J. Waters, Baiba Lace, Daniela Buhas, Serge Gravel, Denis Cyr, Renée‐Myriam Boucher, Geneviève Bernard, Sébastien Lévesque, Bruno Maranda

“…The classical phenotype of HSD10MD in affected males is an infantile‐onset progressive neurodegenerative disorder associated with severe mitochondrial dysfunction. …”
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Cellular Bioenergetics and AMPK and TORC1 Signalling in Blood Lymphoblasts Are Biomarkers of Clinical Status in FMR1 Premutation Carriers by Danuta Z. Loesch, Bruce E. Kemp, Bruce E. Kemp, Minh Q. Bui, Paul R. Fisher, Claire Y. Allan, Oana Sanislav, Kevin R. W. Ngoei, Anna Atkinson, Flora Tassone, Flora Tassone, Sarah J. Annesley, Elsdon Storey

“…Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder affecting carriers of premutation alleles (PM) of the X-linked FMR1 gene, which contain CGG repeat expansions of 55–200 range in a non-coding region. …”
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