Identify Down syndrome transcriptome associations using integrative analysis of microarray database and correlation-interaction network by Min Chen, Jiayan Wang, Yingjun Luo, Kailing Huang, Xiaoshun Shi, Yanhui Liu, Jin Li, Zhengfei Lai, Shuya Xue, Haimei Gao, Allen Chen, Dunjin Chen

“…Dysregulation of lncRNA is correlated to human diseases including neurological disorders. Here, we developed a multi-step bioinformatics analysis to study the functions of a particular Down syndrome-associated gene DSCR9 including the lncRNAs. …”
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Assessment of aphasia: dialectal and cultural considerations in neurology by J. Peña-Casanova, L. Vinaixa, F. Diéguez-Vide, N. Gramunt-Fombuena, A. Soler-Campillo

“…Introduction: In the context of neurological disorders, language assessment is traditionally based on the use of the standard language of the community in which the assessment is performed. …”
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Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude by Latha Kadalayil, Md. Zahangir Alam, Cory Haley White, Akram Ghantous, Esther Walton, Olena Gruzieva, Simon Kebede Merid, Ashish Kumar, Ritu P. Roy, Olivia Solomon, Karen Huen, Brenda Eskenazi, Peter Rzehak, Veit Grote, Jean-Paul Langhendries, Elvira Verduci, Natalia Ferre, Darek Gruszfeld, Lu Gao, Weihua Guan, Xuehuo Zeng, Enrique F. Schisterman, John F. Dou, Kelly M. Bakulski, Jason I. Feinberg, Munawar Hussain Soomro, Giancarlo Pesce, Nour Baiz, Elena Isaevska, Michelle Plusquin, Marina Vafeiadi, Theano Roumeliotaki, Sabine A. S. Langie, Arnout Standaert, Catherine Allard, Patrice Perron, Luigi Bouchard, Evelien R. van Meel, Janine F. Felix, Vincent W. V. Jaddoe, Paul D. Yousefi, Cecilia H. Ramlau-Hansen, Caroline L. Relton, Elmar W. Tobi, Anne P. Starling, Ivana V. Yang, Maria Llambrich, Gillian Santorelli, Johanna Lepeule, Lucas A. Salas, Mariona Bustamante, Susan L. Ewart, Hongmei Zhang, Wilfried Karmaus, Stefan Röder, Ana Claudia Zenclussen, Jianping Jin, Wenche Nystad, Christian M. Page, Maria Magnus, Dereje D. Jima, Cathrine Hoyo, Rachel L. Maguire, Tuomas Kvist, Darina Czamara, Katri Räikkönen, Tong Gong, Vilhelmina Ullemar, Sheryl L. Rifas-Shiman, Emily Oken, Catarina Almqvist, Robert Karlsson, Jari Lahti, Susan K. Murphy, Siri E. Håberg, Stephanie London, Gunda Herberth, Hasan Arshad, Jordi Sunyer, Regina Grazuleviciene, Dana Dabelea, Régine P. M. Steegers-Theunissen, Ellen A. Nohr, Thorkild I. A. Sørensen, Liesbeth Duijts, Marie-France Hivert, Vera Nelen, Maja Popovic, Manolis Kogevinas, Tim S. Nawrot, Zdenko Herceg, Isabella Annesi-Maesano, M. Daniele Fallin, Edwina Yeung, Carrie V. Breton, Berthold Koletzko, Nina Holland, Joseph L. Wiemels, Erik Melén, Gemma C. Sharp, Matt J. Silver, Faisal I. Rezwan, John W. Holloway

“…The DMRs were associated with genes of known functions in tumorigenesis, psychiatric/neurological disorders, inflammation, or immunity, amongst others. …”
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Vanillic Acid, a Bioactive Phenolic Compound, Counteracts LPS-Induced Neurotoxicity by Regulating c-Jun N-Terminal Kinase in Mouse Brain by Rahat Ullah, Muhammad Ikram, Tae Ju Park, Riaz Ahmad, Kamran Saeed, Sayed Ibrar Alam, Inayat Ur Rehman, Amjad Khan, Ibrahim Khan, Min Gi Jo, Myeong Ok Kim

“…Taken together; we suggest that neuroprotective effects of V.A against LPS-induced neurotoxicity might be via inhibition of LPS/RAGE mediated JNK signaling pathway; and encourage future studies that V.A would be a potential neuroprotective and neurotherapeutic candidate in various neurological disorders.…”
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Hyperbaric air mobilizes stem cells in humans; a new perspective on the hormetic dose curve by Kent J. MacLaughlin, Gregory P. Barton, Rudolf K. Braun, Julia E. MacLaughlin, Jacob J. Lamers, Mathew D. Marcou, Marlowe W. Eldridge

“…Extensive use in Europe and North America followed throughout the 19th century to treat pulmonary and neurological disorders. HBA reached its zenith in the early 20th century when cyanotic, moribund “Spanish flu pandemic” patients turned normal color and regained consciousness within minutes after HBA treatment. …”
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Global, regional, and national time trends in incidence for migraine, from 1990 to 2019: an age-period-cohort analysis for the GBD 2019 by Luying Fan, Yuhang Wu, Jiehua Wei, Fan Xia, Yufeng Cai, Senmao Zhang, Junxiang Miao, Yunzhe Zhou, Chu Liu, Wei Yan, Dan Liu, Lizhang Chen, Tingting Wang

“…Conclusions Migraine is still an important contributor to the global burden of neurological disorders worldwide. Temporal trends in migraine incidence are not commensurate with socioeconomic development and vary widely across countries. …”
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Late diagnosis of human immunodeficiency virus infection is linked to higher rates of epilepsy in children in the Eastern Cape of South Africa by Isabel A. Michaelis, Maryke Nielsen, Craig Carty, Markus Wolff, Caroline A. Sabin, John S. Lambert

“…Background: Human immunodeficiency virus (HIV)-positive children may present with a wide range of neurological disorders. Among these, epilepsy is of key concern because of its lifelong impact and potential for damage to the central nervous system (CNS). …”
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Effect of neonatal melatonin administration on behavioral and brain electrophysiological and redox imbalance in rats by Amanda de Oliveira Araújo, Maria Luísa Figueira-de-Oliveira, Arthur Gabriel Alves Furtado de Carvalho Noya, Vitor Palmares Oliveira e Silva, Jennyfer Martins de Carvalho, Leucio Duarte Vieira Filho, Rubem Carlos Araújo Guedes

“…IntroductionMelatonin (MLT) reportedly has beneficial effects in neurological disorders involving brain excitability (e.g., Epilepsy and Migraine) and behavioral patterns (e.g., Anxiety and Depression). …”
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Cross-sectional, hospital-based analysis of headache types using ICHD-3 criteria in the Middle East, Asia, and Africa: the Head-MENAA study by H. Genc, B. Baykan, H. Bolay, D. Uluduz, I. Unal-Cevik, N. Kissani, O. Luvsannorov, M. Togha, A. A. Ozdemir, A. Ozge, on behalf of Head-MENAA study group

“…Abstract Background Headaches are frequent neurological disorders that are yet to be unveiled and treated comprehensively worldwide. …”
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Assessment of celecoxib, a selective cox-2 inhibitor, as a neuroprotective agent in alzheimer’s model of rats by Saxena, Anil Kumar, Noor, Mohd. Fadly, Talib, Norlelawati A.

“…Since neuroinflammation, leading to neuronal apoptosis and death, is one of the mechanisms which is thought to play a significant role in chronic degenerative neurological disorders like Alzheimer’s disease, the present study was planned to assess the neuroprotective role of celecoxib, a selective COX-2 inhibitor, in Alzheimer’s model of rats (2VO). …”
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Brain White Matter Structure and Amyloid Deposition in Black and White Older Adults: The ARIC‐PET Study by Keenan A. Walker, Noah Silverstein, Yun Zhou, Timothy M. Hughes, Clifford R. Jack, David S. Knopman, A. Richey Sharrett, Dean F. Wong, Thomas H. Mosley, Rebecca F. Gottesman

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Comparison of medical and social characteristics and quality of life of patients with primary- and secondary-progressive multiple sclerosis by Ya. V. Vlasov, N. G. Polyarnaya, A. N. Boyko

“…Another unfavorable course of MS is primary progressive MS (PPMS) when there is a steady increase in neurological disorders from the very beginning of the disease.Objective: to compare medical and social characteristics and changes in quality of life (QoL) indexes in patients with PPMS and SPMS.Patients and methods. …”
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Ideal Cardiovascular Health and Biomarkers of Subclinical Brain Aging: The Northern Manhattan Study by Hannah Gardener, Michelle Caunca, Chuanhui Dong, Ying Kuen Cheung, Noam Alperin, Tatjana Rundek, Mitchell S. V. Elkind, Clinton B. Wright, Ralph L. Sacco

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Biomechanical analysis of countermovement jump in people with cerebral palsy Análisis biomecánico del salto vertical con contramovimiento en personas con parálisis cerebral by K. Gianikellis, A. Bote, J. M.ª Pulido, A. Pérez

“…The obtained results confirm the accomplishment of the biomechanical principle of the initial force as in the case of persons not affected by neurological disorders. Finally the calculated ratio between the breaking impulse and the acceleration impulse is very near to optimum values. …”
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Gut Microbiome and Bile Acid Metabolism Induced the Activation of CXCR5+ CD4+ T Follicular Helper Cells to Participate in Neuromyelitis Optica Spectrum Disorder Recurrence by Xi Cheng, Luyao Zhou, Zhibin Li, Shishi Shen, Yipeng Zhao, Chunxin Liu, Xiaonan Zhong, Yanyu Chang, Allan G. Kermode, Allan G. Kermode, Allan G. Kermode, Wei Qiu

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Epidemiology and patient journey of Rett syndrome in the United States: a real-world evidence study by Damian May, Kalé Kponee-Shovein, Malena Mahendran, Nathaniel Downes, Kristy Sheng, Patrick Lefebvre, Wendy Y. Cheng

“…Among 5,940 female patients (pediatric: 3,078; adult: 2,862) with mean observation period of 2.04 years, the most prevalent clinical manifestations were neurological disorders (72.8%), gastrointestinal/nutritional disorders (41.9%), and orthopedic disorders (34.6%). …”
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Venous Thromboembolism in Patients Hospitalized for COVID-19 in a Non-Intensive Care Unit by Magdalena Mackiewicz-Milewska, Małgorzata Cisowska-Adamiak, Jerzy Pyskir, Iwona Świątkiewicz

“…No significant associations were found between VTE risk and other analyzed factors; however, VTE was more likely to occur in patients with a history of VTE, neurological disorders, chronic pulmonary or kidney disease, atrial fibrillation, obesity, and Delta variant infection. …”
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The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study by Farzane Sivandzade, Faleh Alqahtani, Ali Sifat, Luca Cucullo

“…To this end, tobacco smoke (TS) has been shown to promote vascular inflammation, neurovascular impairments, and risk of cerebrovascular and neurological disorders through oxidative stress (OS) stimuli targeting the blood-brain barrier (BBB) endothelium among others. …”
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Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration by Oshri Avraham, Jimmy Le, Kathleen Leahy, Tiandao Li, Tiandao Li, Guoyan Zhao, Guoyan Zhao, Valeria Cavalli, Valeria Cavalli, Valeria Cavalli

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Enzyme Replacement Therapy with Pabinafusp Alfa for Neuronopathic Mucopolysaccharidosis II: An Integrated Analysis of Preclinical and Clinical Data by Roberto Giugliani, Ana Maria Martins, Torayuki Okuyama, Yoshikatsu Eto, Norio Sakai, Kimitoshi Nakamura, Hideto Morimoto, Kohtaro Minami, Tatsuyoshi Yamamoto, Mariko Yamaoka, Toshiaki Ikeda, Sairei So, Kazunori Tanizawa, Hiroyuki Sonoda, Mathias Schmidt, Yuji Sato

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