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Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease
Published 2022-12-01Get full text
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6603
Astaxanthin Suppresses PM2.5-Induced Neuroinflammation by Regulating Akt Phosphorylation in BV-2 Microglial Cells
Published 2020-09-01“…Recent studies suggest that fine particulate matter of less than 2.5 (PM2.5), common in air pollution, can reach the brain, potentially resulting in the development and acceleration of various neurological disorders including Alzheimer’s disease, Parkinson’s disease, and other forms of dementia, but the underlying pathological mechanisms are not clear. …”
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6604
Impairment in Functioning and Quality of Life in Patients with Idiopathic Hypersomnia: The Real World Idiopathic Hypersomnia Outcomes Study (ARISE)
Published 2023-08-01“…The Real World Idiopathic Hypersomnia Outcomes Study (ARISE) evaluated the daily functioning, relationships, cognition, emotional well-being, and productivity/employment of participants with idiopathic hypersomnia.Patients and Methods: ARISE was a US-based virtual cross-sectional survey comprising multiple patient-reported outcome measures (Functional Outcomes of Sleep Questionnaire, short version [FOSQ-10], Quality of Life in Neurological Disorders [Neuro-QoL] Social Roles and Stigma domains, British Columbia Cognitive Complaints Inventory [BC-CCI], Patient Health Questionnaire [PHQ-9], and the Work Productivity and Activity Impairment Questionnaire: Specific Health Problem [WPAI:SHP]). …”
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6605
Non-target GC–MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice
Published 2023-06-01Get full text
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6606
Distribution, Ecology, Chemistry and Toxicology of Plant Stinging Hairs
Published 2021-02-01“…The physiological effects of stinging hairs on humans vary widely between stinging plants and range from a slight itch, skin rash (urticaria), and oedema to sharp pain and even serious neurological disorders such as neuropathy. Numerous studies have attempted to elucidate the chemical basis of the physiological effects. …”
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6607
Identification of mitochondrial related signature associated with immune microenvironment in Alzheimer’s disease
Published 2023-07-01“…Five hub MitoDEGs associated with neurological disorders were identified by biological function examination. …”
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6608
Inclusion of calf implants for the correction of lower limb amyotrophy Inclusão de implantes de panturrilha na correção das amiotrofias dos membros inferiores
Published 2011-09-01“…In 4 of 5 patients, the desired result was obtained after a single surgical procedure, and no patient developed capsular contracture, compartment syndrome, circulatory disorders, neurological disorders, or infections. CONCLUSIONS: Calf augmentation in patients with lower limb amyotrophy did not correct the associated functional deficit, but resulted in a high level of satisfaction with regard to the esthetic improvement of the limb, thus improving the quality of life of these patients.…”
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6609
Associations Between Repetitive Negative Thinking and Objective and Subjective Sleep Health in Cognitively Healthy Older Adults
Published 2024-03-01“…Lydia B Munns,1,2,* Harriet Demnitz-King,1,* Claire André,3 Stéphane Rehel,3 Valentin Ourry,3 Vincent de La Sayette,4 Denis Vivien,3,5 Gaël Chételat,3 Géraldine Rauchs,3,* Natalie L Marchant1,* On behalf of the Medit-Ageing Research Group1Division of Psychiatry, University College London, London, UK; 2Department of Psychology, York University, York, UK; 3Normandie Univ, UNICAEN, INSERM, U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Neuropresage Team, GIP Cyceron, Caen, France; 4Service de Neurologie, CHU de Caen-Normandie, Caen, France; 5Département de Recherche Clinique, CHU Caen-Normandie, Caen, France*These authors contributed equally to this workCorrespondence: Natalie L Marchant, Division of Psychiatry, University College London, London, UK, Email n.marchant@ucl.ac.uk Lydia B Munns, Department of Psychology, York University, York, United Kingdom, Email lydbmunns@gmail.comObjective: Poor sleep and high levels of repetitive negative thinking (RNT), including future-directed (ie, worry) and past-directed (ie, brooding) negative thoughts, have been associated with markers of dementia risk. …”
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6610
Claudicação na criança Limping in children
Published 2009-01-01“…Among infants (1 to 3 years old), diagnosis will most likely be: transitory synovitis, septic arthritis, neurological disorders (mild brain palsy (BP) and muscular dystrophy), congenital hip dislocation (CHD), varus thigh, juvenile rheumatoid arthritis (JRA) and neoplasias (osteoid osteoma, leukemia); in the scholar age group, between 4 and 10 years old, in addition to the diagnoses above, Legg-Calvé-Perthes disease, discoid meniscus, inferior limbs discrepancy and unspecific muscular pain; in adolescents (11 to 15 years old): slipped capital femoral epiphysis, congenital hip dislocation, chondrolysis, overuse syndromes, dissecans osteochondritis, and tarsal coalition. …”
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Integrating single-nucleus sequence profiling to reveal the transcriptional dynamics of Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis
Published 2023-09-01“…Additionally, the identification of arctigenin as a potential therapeutic drug for AD, PD, and MS further highlights its potential in treating these neurological disorders. These discoveries lay the groundwork for future research and interventions to enhance our understanding and treatment of AD, PD, and MS.…”
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A novel framework for in-vivo diffusion tensor distribution MRI of the human brain
Published 2023-05-01Get full text
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Statin sebagai Protektor Otak pada Cedera Otak Traumatik
Published 2017-02-01“…Statin, 3-hydroxy-3-methyglutaryl coenzym-A (HMG CoA) reductase inhibitor is hypolipidemik drug which has pleiotropic effect in cholesterol-independen manner and suggest potential effect in neurologic disorder such as decreased hemostatic and decreased thrombotic effect and cascade coagulation, increased fibrinolytic and anticoagulation cascade, improve endothelial function, increase nitric oxide bioaviability, antioxidan, immunomodulation and anti-inflammatory activity and stabilize plaque atheroslerotic. …”
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6615
Applied Machine Learning Techniques to Diagnose Voice-Affecting Conditions and Disorders: Systematic Literature Review
Published 2023-07-01“…ObjectiveThis study aims to summarize a comprehensive view of research on voice-affecting disorders that uses ML techniques for diagnosis and monitoring through voice samples where systematic conditions, nonlaryngeal aerodigestive disorders, and neurological disorders are specifically of interest. …”
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Oligoclonal IgG bands in the cerebrospinal fluid of portuguese patients with multiple sclerosis: negative results indicate benign disease Bandas oligoclonais da IgG no líquido céfa...
Published 2005-06-01“…Paired CSF/serum samples of 406 patients with neurological disorders were submitted to isoelectric focusing with immunodetection of IgG. …”
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Improving levodopa delivery: IPX203, a novel extended-release carbidopa-levodopa formulation
Published 2023-01-01Get full text
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6619
Immature functional development of lumbar locomotor networks in adult Irf8−/− mice
Published 2024-01-01Get full text
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38 Plasma proteomic signature of motoric cognitive risk syndrome
Published 2023-04-01Get full text
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