Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown by Moore-Dotson Johnnie M, Papke Jason B, Harkins Amy B

“…We measured catecholamine release from single vesicles by amperometry and neuropeptide Y release from populations of cells by an immunoassay. …”
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The predictive capacity of hypersympathicotonia in post-stroke patients with III stage hypertension by I. N. Voloshyna

“…The evaluation of neuropeptide Y plasma concentration and LF/ HF ratio in post-stroke hypertensive patients has been done. …”
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ProSAAS-derived peptides are differentially processed and sorted in mouse brain and AtT-20 cells. by Jonathan H Wardman, Lloyd D Fricker

“…In mouse hypothalamus, PEN and big LEN colocalize with neuropeptide Y. In the present study, little LEN and SAAS were detected in mouse hypothalamus but not in cell bodies of neuropeptide Y-expressing neurons. …”
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The role of ghrelin and serotonin in the control of eating behavior in patients with obesity and diabetes mellitus type 2 by A.M. Urbanovych, F.V. Laniush

“…Activation of this signa­ling system by melanocortins leads to appetite decrease and causes a feeling of satiety. Neuropeptide Y and agouti-related protein act antagonistically and enhance hunger. …”
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Effect of Crude Saponin of Korean Red Ginseng on High-Fat Diet-Induced Obesity in the Rat by Ji Hyun Kim, Dae Hyun Hahm, Deck Chun Yang, Jang Hyun Kim, Hye Jung Lee, Insop Shim

“…Keywords:: crude saponin of Korean red ginseng, neuropeptide Y, leptin, hypothalamus, antiobesity…”
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Heterogeneity And Diversity Of Striatal GABAergic Interneurons by James M Tepper, Fatuel eTecuapetla, Tibor eKoos, Osvaldo eIbanez-Sandoval

“…The second best known interneuron type expresses a number of neuropeptides and enzymes, including neuropeptide Y, somatostatin and nitric oxide synthase. …”
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Interference of angiotensin-converting enzyme inhibition with vasoactive peptides in the coronary circulation of dogs. by Bauer, B, Neubauer, S, Spindler, M, Dürr, R, Becker, H, Ertl, G

“…Because these drugs may interfere with hormone systems other than the reninangiotensin system (RAS), we studied modulation of the coronary effects of neurotensin, neuropeptide Y (NPY), and endothelin-1 (ET-1) by pretreatment with captopril in anesthetized, open-chest dogs. …”

SPANISH MULTICENTRIC STUDY ABOUT NUTRITION-INFLAMATIONhn WITH MID DILUTION (ENIMID STUDY): PRELIMINARY RESULTS by Barril G, Anaya S, Vozmediano C, Celayeta AO, Novillo R, Garcia-Bernal V, Beired I, Huarte E, JC Chacón, Martín J, Santana H, Grande J, Chacon JC, Martin Garcia, Sousa F, Martin J Gago, Sánchez R, López-Montes A, R de Gracia, Tornero F, Usón J, Pousa M, Cigarran S, Giorgi M, Rdez Cubillo B, Herrero J, Izdo MJ, Abaigar P

“…The parameters analyzed each 3 months are: urea, β2microglobuline, albumin, pre-albumin, CRP, fibrinogen, IL6, IL10, leptin, adiponectin, neuropeptide Y, body composition by BIVA parameters and apetite and quality life surveys. …”
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Prawn Shell Chitosan Exhibits Anti-Obesogenic Potential through Alterations to Appetite, Affecting Feeding Behaviour and Satiety Signals In Vivo. by Áine M Egan, John V O'Doherty, Stafford Vigors, Torres Sweeney

“…Pigs receiving dietary chitosan had an up-regulation in gene expression of growth hormone receptor (P<0.05), Peroxisome proliferator activated receptor gamma (P<0.01), neuromedin B (P<0.05), neuropeptide Y receptor 5 (P<0.05) in hypothalamic nuclei and neuropeptide Y (P<0.05) in the jejunum. …”
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Towards Probing Conformational States of Y2 Receptor Using Hyperpolarized ¹²⁹Xe NMR by Peter Schmidt, Alexander Vogel, Benedikt Schwarze, Florian Seufert, Kai Licha, Virginia Wycisk, Wolfgang Kilian, Peter W. Hildebrand, Lorenz Mitschang

“…Here, the application of NMR of hyperpolarized ¹²⁹Xe for the detection of the conformational states of human neuropeptide Y2 receptor is introduced. The xenon trapping cage molecule cryptophane-A attached to a cysteine in extracellular loop 2 of the receptor facilitates chemical exchange saturation transfer experiments without and in the presence of native ligand neuropeptide Y. …”
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Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation by Xia Zefeng, Fritze Danielle, Zhang Chao, Wu Xiaobin, Zhang Weizhen, Chai Biaoxin, Li Ji-Yao, Patterson Cam, Mulholland Michael W

“…Ankyrin repeat and SOCS box containing protein 4 (Asb-4) is expressed in neuropeptide Y and proopiomelanocortin (POMC) neurons in the arcuate nucleus, target neurons in the regulation of food intake and metabolism by insulin and leptin. …”
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Neurogliaform neurons form a novel inhibitory network in the hippocampal CA1 area. by Price, C, Cauli, B, Kovacs, E, Kulik, A, Lambolez, B, Shigemoto, R, Capogna, M

“…Single-cell reverse transcription-PCR showed that these neurons were GABAergic and that the majority expressed mRNA for neuropeptide Y. Most neurogliaform neurons tested were immunoreactive for alpha-actinin-2, and many stratum lacunosum moleculare interneurons coexpressed alpha-actinin-2 and neuropeptide Y. …”

Effect of Xiaoyao San on the brain-gut axis in rats after chronic immobilization stress by Qun Liu, Qingyu Ma, Yueyun Liu, Xiaojuan Li, Youming Jiang, Zhiyi Yan, Qiuxia Pan, Na Li, Xiaohui Bai, Jiaxu Chen

“…Specifically, the levels of neuropeptide Y (NPY) and neuropeptide Y receptor Y5, which are secreted by the hypothalamus and promote digestive function, were increased in the Xiaoyao San-treated group compared with the model group. …”
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Characterization of GABAergic Marker Expression in the Chronic Unpredictable Stress Model of Depression by Mounira Banasr, Ashley Lepack, Corey Fee, Vanja Duric, Jaime Maldonado-Aviles, Ralph DiLeone, Etienne Sibille, Ronald S. Duman, Gerard Sanacora

“…In addition, our results provide clear evidence of reduced markers of interneuron population(s), namely somatostatin and neuropeptide Y, in the prefrontal cortex, suggesting these cell types may be selectively vulnerable to chronic stress. …”
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The regulation of hypothalamic corticotropin-releasing factor release: in vitro studies. by Grossman, A, Costa, A, Navarra, P, Tsagarakis, S

“…Using this technique, we have found stimulation of secretion by noradrenaline, acetylcholine, serotonin, neuropeptide Y, and interleukins 1 and 6; inhibitory modulation was shown by GABA, substance P, atrial natriuretic peptide, opioid peptides and precursors of nitric oxide. …”

Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus by Yury M. Morozov, Marco Koch, Pasko Rakic, Tamas L. Horvath

“…Keywords: Hypothalamus, Arcuate nucleus, Agouti-related protein, Neuropeptide Y, Electron microscopy, 3D reconstruction…”
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Empagliflozin protects against atherosclerosis progression by modulating lipid profiles and sympathetic activity by Yihai Liu, Jiamin Xu, Mingyue Wu, Biao Xu, Lina Kang

“…In addition, empagliflozin decreased body weight (-3.27 g, P = 0.002), lipid profiles (TC: [-15.3 mmol/L, P = 0.011]; TG: [-2.4 mmol/L, P < 0.001]; LDL: [-2.9 mmol/L, P = 0.010]), RAAS (renin [-9.3 ng/L, P = 0.047]; aldosterone [-16.7 ng/L, P < 0.001]) and sympathetic activity (norepinephrine [-8.9 ng/L, P = 0.019]; neuropeptide Y [-8.8 ng/L, P = 0.002]). However, the anti-inflammatory effect of empagliflozin was not significantly evident. …”
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A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (<it>AMPA 2</it>, <it>... by Steinberg-Epstein Robin, Modahl Charlotte B, Hanouni Mona, Mays Lee Z, Flodman Pamela L, Woodroffe Abigail, Ramanathan Subhadra, Bocian Maureen E, Spence M Anne, Smith Moyra

“…Glutamate receptors maintain structural and functional plasticity of synapses. Neuropeptide Y and its receptors <it>NPY1R </it>and <it>NPY5R </it>play a role in hippocampal learning and memory. …”
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Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy by Esbjörn Melin, Avtandil Nanobashvili, Una Avdic, Casper R. Gøtzsche, My Andersson, David P.D. Woldbye, Merab Kokaia

“…We investigated the seizure-suppressant potential of combinatorial neuropeptide Y and Y2 receptor single vector gene therapy based on adeno-associated virus serotype 1 (AAV1) in rats. …”
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Neuroeffector Mechanisms Involved in the Regulation of Dog Splenic Arterial Tone by Shigetoshi Chiba, Xiao-Ping Yang

“…It has been recognized that sympathetic neurons release several transmitters but mainly adenosine 5'-triphosphate (ATP), noradrenaline, and neuropeptide Y (NPY). Recently, we reported that periarterial nerve electrical stimulation (PNS) produced biphasic vasoconstrictions consisting of an initial transient, predominantly P2X-purinoceptor-mediated constriction followed by a prolonged, α1-adrenoceptor-mediated one in canine isolated splenic arteries. …”
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