Sport, doping and female fertility by Sandro La Vignera, Rosita A. Condorelli, Rossella Cannarella, Ylenia Duca, Aldo E. Calogero

“…The first paragraph investigates the effects of physical activity on ovarian function, analyzing in particular the changes concerning the serum concentrations of follicle-stimulating hormone, luteinizing hormone, prolactin, growth hormone, thyroid hormones, leptin, ghrelin, neuropeptide Y. The second paragraph analyzes the effects of doping on the hypothalamic-pituitary-ovarian axis. …”
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Is there an association between NPY and neuroticism? by Cotton, C, Flint, J, Campbell, T

“…Here we show that the claims of Zhou et al. that neuropeptide Y (NPY) diplotype-predicted expression is correlated with trait anxiety (neuroticism) is not replicated in a data set consisting of phenotypically extreme individuals drawn from a large (n = 88,142) non-clinical population. …”

Emerging Signaling Pathway in Arcuate Feeding-Related Neurons: Role of the Acbd7 by Damien Lanfray, Denis Richard

“…In the last three decades, focus was put on the metabolic role played by the hypothalamic neurons expressing proopiomelanocortin (POMC) and cocaine and amphetamine regulated transcript (CART) and the neurons co-localizing agouti-related peptide (AgRP), neuropeptide Y (NPY), and gamma-aminobutyric acid (GABA). …”
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Neuroendocrine and Molecular Interactions in Eating Disorders by Selma Bozkurt Zincir

“…Certain hormones, neurotransmitters and other molecules which might have effect on the basis of eating disorders can be listed as estrogen, serotonin, leptin, ghreline, alpha-melanocyte stimulating hormone, cholecystokinin, dopamine, noradrenaline, brain-derived neurotropic factor, agouti-related protein, neuropeptide-Y, opioids and their receptors, thiamine, zinc, omega-3 acids. …”
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Role of Reactive Oxygen Species in Hypothalamic Regulation of Energy Metabolism by Sabrina Diano

“…These review summarizes the published recent data on the effect of ROS levels in the regulation of neuronal function, including that of hypothalamic melanocortin neurons, pro-opiomelanocortin and neuropeptide Y-/agouti related peptide-neurons, in the modulation of food intake.…”
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Integration of Nutrient Sensing in Fish Hypothalamus by José L. Soengas

“…Changes in these signaling pathways would control phosphorylation of transcription factors cAMP response-element binding protein (CREB), forkhead box01 (FoxO1), and brain homeobox transcription factor (BSX) leading to food intake inhibition through changes in the expression of neuropeptide Y (NPY), agouti-related peptide (AgRP), pro-opio melanocortin (POMC), and cocaine and amphetamine-related transcript (CART). …”
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A fat-derived metabolite regulates a peptidergic feeding circuit in Drosophila. by Do-Hyoung Kim, Minjung Shin, Sung-Hwan Jung, Young-Joon Kim, Walton D Jones

“…We found Sptr expression is required in four adult neurons that express neuropeptide F (NPF), the fly homologue of the vertebrate appetite regulator neuropeptide Y (NPY). As expected, feeding flies BH4 rescues the loss of Punch and Purple in the fat body and the loss of Sptr in NPF neurons. …”
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Neuropeptidergic Regulation of Food Intake in the Neonatal Chick: A Review by Mitsuhiro Furuse, Haruka Yamane, Shozo Tomonaga, Yousuke Tsuneyoshi, D. Michael Denbow

“…However, the orexigenic factors are limited to neuropeptide Y, opioid, prolactin releasing peptide and gonadotropin-inhibitory hormone. …”
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Two types of somatostatin-expressing GABAergic interneurons in the superficial layers of the mouse cingulate cortex. by Therese Riedemann, Tobias Straub, Bernd Sutor

“…In particular, all SOM+ interneurons expressing calbindin but no calretinin could be classified as group I GIN, whereas all but one neuropeptide Y- and calretinin-positive interneurons were found in group II.…”
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DNA Methylation in the Hypothalamic Feeding Center and Obesity

“…The DNA methylation levels of proopiomelanocortin (Pomc) and neuropeptide Y (Npy) in the hypothalamic feeding center, a key region controlling systemic energy balance, are affected by diet. …”
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Computational prediction of alanine scanning and ligand binding energetics in G-protein coupled receptors. by Lars Boukharta, Hugo Gutiérrez-de-Terán, Johan Aqvist

“…A smooth stepwise scheme for free energy perturbation calculations is derived and applied to a series of thirteen alanine mutations of the human neuropeptide Y1 receptor and series of eight analogous antagonists. …”
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Determinants of body weight regulation in humans by Milene Moehlecke, Luis Henrique Canani, Lucas Oliveira Junqueira e Silva, Manoel Roberto Maciel Trindade, Rogerio Friedman, Cristiane Bauermann Leitão

“…In this review, we examine the role of systemic mediators such as leptin, ghrelin and insulin, which act in the central nervous system by activating or inhibiting neuropeptide Y, Agouti-related peptide protein, melanocortin, transcript related to cocaine and amphetamine, and others. …”
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Regulatory Peptides in Asthma by Katarzyna Kaczyńska, Dominika Zając, Piotr Wojciechowski, Monika Jampolska

“…Some of them exacerbate asthma symptoms, such as neuropeptide Y and tachykinins, while others have ameliorating properties, such as nociception, neurotensin or β-defensin 2. …”
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Leptin Increases: Physiological Roles in the Control of Sympathetic Nerve Activity, Energy Balance, and the Hypothalamic–Pituitary–Thyroid Axis by Davide Martelli, Virginia L. Brooks

“…These responses are mediated largely by suppression of the actions of leptin in the hypothalamus, most notably on arcuate nucleus (ArcN) orexigenic neuropeptide Y neurons and anorexic pro-opiomelanocortin neurons. …”
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Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats by Boldizsár Czéh, Boldizsár Czéh, Boldizsár Czéh, Irina Vardya, Zsófia Varga, Fabia Febbraro, Dávid Csabai, Lena-Sophie Martis, Kristoffer Højgaard, Kim Henningsen, Elena V. Bouzinova, Attila Miseta, Kimmo Jensen, Kimmo Jensen, Ove Wiborg, Ove Wiborg

“…Post mortem quantitative histopathology was used to examine the effect of stress on parvalbumin (PV)-, calretinin- (CR), calbindin- (CB), cholecystokinin- (CCK), somatostatin-(SST) and neuropeptide Y-positive (NPY+) GABAergic neuron numbers in all cortical subareas of the mPFC (anterior cingulate (Cg1), prelimbic (PrL) and infralimbic (IL) cortexes). …”
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Peripheral Insulin Doesn’t Alter Appetite of Broiler Chicks by Lei Liu, Shaohua Xu, Xiaojuan Wang, Hongchao Jiao, Hai Lin

“…Peripheral insulin treatment of 10 IU for 2 or 4 h did not significantly affect the hypothalamic genes expression of neuropeptide Y, proopiomelanocortin, corticotropin-releasing factor and insulin receptors (p>0.05). …”
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A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening. by Yasuhito Shimada, Minoru Hirano, Yuhei Nishimura, Toshio Tanaka

“…Gene expression analysis of brain-derived neurotrophic factor (bdnf), knockdown of appetite-regulating genes (neuropeptide Y, preproinsulin, melanocortin 4 receptor, agouti related protein, and cannabinoid receptor 1), and the administration of clinical appetite suppressants (fluoxetine, sibutramine, mazindol, phentermine, and rimonabant) revealed the similarity among mechanisms regulating appetite in zebrafish and mammals. …”
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Modulation of Microbiota-Gut-Brain Axis by Berberine Resulting in Improved Metabolic Status in High-Fat Diet-Fed Rats by Honglin Sun, Ningjian Wang, Zhen Cang, Chaoxia Zhu, Li Zhao, Xiaomin Nie, Jing Cheng, Fangzhen Xia, Hualing Zhai, Yingli Lu

“…In addition, the microbiota-gut-brain axis was found to be modulated, including structural and diversity changes of microbiota, elevated serum glucagon-like peptide-1 and neuropeptide Y level, decreased orexin A level, up-regulated glucagon-like peptide-1 receptor mRNA level as well as ultra-structural improvement of the hypothalamus. …”
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Discovery of Small-Molecule Modulators of the Human Y4 Receptor. by Gregory Sliwoski, Mario Schubert, Jan Stichel, David Weaver, Annette G Beck-Sickinger, Jens Meiler

“…The human neuropeptide Y4 receptor (Y4R) and its native ligand, pancreatic polypeptide, are critically involved in the regulation of human metabolism by signaling satiety and regulating food intake, as well as increasing energy expenditure. …”
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Molecular and electrophysiological characterization of GFP-expressing CA1 interneurons in GAD65-GFP mice. by Corette J Wierenga, Fiona E Müllner, Ilka Rinke, Tara Keck, Valentin Stein, Tobias Bonhoeffer

“…GFP-labeled interneurons can be subdivided according to the (partially overlapping) expression of neuropeptide Y (42±3%), cholecystokinin (25±3%), calbindin (20±2%) or calretinin (20±2%). …”
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