Central Pathways Integrating Metabolism and Reproduction in Teleosts by Md eShahjahan, Takashi eKitahashi, Ishwar S Parhar

“…The hypothalamus plays a crucial role in the regulation of both energy balance and reproduction, and contains a number of neuropeptides, including gonadotropin-releasing hormone (GnRH), orexin, neuropeptide-Y (NPY), ghrelin, pituitary adenylate cyclase-activating polypeptide (PACAP), α-melanocyte stimulating hormone (α-MSH), melanin-concentrating hormone (MCH), cholecystokinin (CCK), 26RFa, nesfatin, kisspeptin, and gonadotropin-inhibitory hormone (GnIH). …”
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Similar Neural Pathways Control Foraging in Mosquitoes and Worms by Jogender Singh, Alejandro Aballay

“…New research shows that pharmacological activation of neuropeptide Y-like receptor (NPYLR) signaling elicits host aversion in female mosquitoes. …”
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Novel insights into the metabolic action of Kiss1 neurons by Rajae Talbi, Victor M Navarro

“…Compelling evidence suggests that Kiss1 neurons of the arcuate nucleus (Kiss1ARC), recently identified as the hypothalamic GnRH pulse generator driving fertility, also participate in the regulation of metabolism through kisspeptinergic and glutamatergic interactions with, at least, proopiomelanocortin (POMC) and agouti-related peptide (AgRP)/neuropeptide Y (NPY) neurons, located in close apposition with Kiss1ARC. …”
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Peptide-Drug Conjugates and Their Targets in Advanced Cancer Therapies by Paul Hoppenz, Sylvia Els-Heindl, Annette G. Beck-Sickinger

“…A special focus was set on the bombesin receptor family and the neuropeptide Y receptor family. In the second part, the specific requirements of peptide-drug conjugates (PDC) and intelligent linker structures as an essential component of PDC are outlined. …”
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Expression of NPY-immunoreactive neurons in the hypothalamus of the cycling ewe. by Anna Wójcik-Gładysz, Marta Wańkowska, Jolanta Polkowska

“…The purpose of the study was to localise neuropeptide Y (NPY) immunoreactive (ir) neurons in the hypothalamus during two phases of the oestrous cycle in the ewe. …”
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The Role of Peptides in Asthma–Obesity Phenotype by Ewelina Russjan

“…Adipokines such as leptin, adiponectin, resistin, and the less studied omentin, chemerin, and visfatin, as well as the gastrointestinal hormones ghrelin, cholecystokinin, glucagon-like peptide-1, and neuropeptides, including substance P or neuropeptide Y, can play a significant role in asthma with obesity. …”
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Peptide tyrosine tyrosine (PYY) as a new strategy for treating obesity by Ahmed Mostafa Mahmoud

“…Objective The objective of this research was to study the role of pancreatic polypeptide family including neuropeptide Y and peptide tyrosine tyrosine (PYY) in obesity development and its metabolic changes. …”
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Is there a correlation between GAD2 gene-243 A>G polymorphism and obesity? by Alkhzouz Camelia, Miclea Diana, Farcas Marius, Bucerzan Simona, Cabau Georgiana, Popp Radu Anghel

“…It is suggested that some polymorphic alleles of GAD2 gene, such as -243A>G, have an increased transcriptional effect compared with the wild type, which results in an increase of GABA in the hypothalamus with the subsequent increase of the neuropeptide Y, thus exacerbating the hunger centre and the appetite. …”
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Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin. by Luís Martins, Diana Fernández-Mallo, Marta G Novelle, María J Vázquez, Manuel Tena-Sempere, Rubén Nogueiras, Miguel López, Carlos Diéguez

“…Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase the expression of agouti-related protein (AgRP) and neuropeptide Y (NPY) in the arcuate nucleus of the hypothalamus (ARC). …”
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Behavior-dependent specialization of identified hippocampal interneurons. by Lapray, D, Lasztoczi, B, Lagler, M, Viney, T, Katona, L, Valenti, O, Hartwich, K, Borhegyi, Z, Somogyi, P, Klausberger, T

“…Recorded parvalbumin-expressing basket interneurons innervated somata and proximal pyramidal cell dendrites, whereas nitric oxide synthase- and neuropeptide Y-expressing ivy cells provided synaptic and extrasynaptic dendritic modulation. …”

Functional Access to Neuron Subclasses in Rodent and Primate Forebrain by Preeti Mehta, Lauren Kreeger, Dennis C. Wylie, Jagruti J. Pattadkal, Tara Lusignan, Matthew J. Davis, Gergely F. Turi, Wen-Ke Li, Matthew P. Whitmire, Yuzhi Chen, Bridget L. Kajs, Eyal Seidemann, Nicholas J. Priebe, Attila Losonczy, Boris V. Zemelman

“…Keywords: inhibitory neurons, somatostatin, parvalbumin, neuropeptide-Y, cell type-specific promoter, adeno-associated virus, rodent, marmoset, macaque, functional in vivo imaging…”
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Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine by Jessica A. Hiemstra, Dong I. Lee, Khalid Chakir, Manuel Gutiérrez‐Aguilar, Kurt D. Marshall, Pamela J. Zgoda, Noelany Cruz Rivera, Daniel G. Dozier, Brian S. Ferguson, Denise M. Heublein, John C. Burnett, Carolin Scherf, Jan R. Ivey, Gianmaria Minervini, Kerry S. McDonald, Christopher P. Baines, Maike Krenz, Timothy L. Domeier, Craig A. Emter

“…ConclusionsBoth saxagliptin and tadalafil prevented increased LV collagen deposition in a manner related to the attenuation of increased plasma neuropeptide Y levels. Saxagliptin appears superior for treating heart failure with preserved ejection fraction, considering its comprehensive effects on integrated LV systolic and diastolic function.…”
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Immune Dysfunction in Uremia 2020 by Gerald Cohen

“…Besides small water-soluble and protein-bound compounds originating from the intestinal microbiome, several molecules in the middle molecular range, e.g., immunoglobulin light chains, retinol-binding protein, the neuropeptides Met-enkephalin and neuropeptide Y, endothelin-1, and the adipokines leptin and resistin, adversely affect immune cells. …”
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Caloric restriction in female reproduction: is it beneficial or detrimental? by Jiayi Sun, Xin Shen, Hui Liu, Siying Lu, Jing Peng, Haibin Kuang

“…Recently it is found that CR significantly affects female reproduction via hypothalamic (corticotropin releasing hormone, neuropeptide Y, agouti-related peptide) and peripheral (leptin, ghrelin, insulin, insulin-like growth factor) mediators, which can regulate the energy homeostasis. …”
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Bone Injury and Repair Trigger Central and Peripheral NPY Neuronal Pathways. by Cecília J Alves, Inês S Alencastre, Estrela Neto, João Ribas, Sofia Ferreira, Daniel M Vasconcelos, Daniela M Sousa, Teresa Summavielle, Meriem Lamghari

“…Here, we addressed the neuropeptide Y (NPY) neuronal arm during the initial stages of bone repair encompassing the inflammatory response and ossification phases in femoral-defect mouse model. …”
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Gut-brain peptides in corticostriatal-limbic circuitry and alcohol use disorders by Chelsea A Vadnie, Jun Hyun ePark, Noha eAbdel Gawad, Ada Man Choi eHo, David J Hinton, Doo-Sup eChoi

“…This review provides a summary of current knowledge on gut-brain peptides focusing on five peptides: neurotensin, glucagon-like peptide 1, ghrelin, substance P, and neuropeptide Y. Our review will be helpful to develop novel therapeutic targets for AUD.…”
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Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle by L Ragionieri, M Botti, F Gazza, L Bo Minelli, F Acone, R Panu, G Palmieri

“…The co-existence of tyrosine hydroxylase with choline acetyltransferase, neuronal nitric oxide synthase, calcitonin gene-related peptide, leuenkephalin, neuropeptide Y, substance P and vasoactive intestinal polypeptide was studied under a fluorescent microscope on cryostat sections. …”
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Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease. by Alice Krezymon, Kevin Richetin, Hélène Halley, Laurent Roybon, Jean-Michel Lassalle, Bernard Francès, Laure Verret, Claire Rampon

“…Those include aberrant expression of neuropeptide Y and reduced levels of calbindin, reflecting a profound remodeling of inhibitory and excitatory circuits in the dentate gyrus. …”
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A systematic review of resilient performance in defence and security settings by Marc Vincent Jones, Nathan Smith, Danielle Burns, Elizabeth Braithwaite, Martin Turner, Andy McCann, Lucy Walker, Paul Emmerson, Leonie Webster, Martin Jones

“…There was mixed evidence for the predictive value of biomarkers, although there was some support for cortisol, dehydroepiandrosterone sulfate (DHEA-S) and neuropeptide-y (NPY), and vagal reactivity. Interventions to improve resilient performance were focused on mindfulness or general psychological skills, with effects generally clearer on cognitive tasks rather than direct performance outcomes in the field. …”
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GIRK2 potassium channels expressed by the AgRP neurons decrease adiposity and body weight in mice. by Youjin Oh, Eun-Seon Yoo, Sang Hyeon Ju, Eunha Kim, Seulgi Lee, Seyun Kim, Kevin Wickman, Jong-Woo Sohn

“…It is well known that the neuropeptide Y (NPY)/agouti-related peptide (AgRP) neurons increase appetite and decrease thermogenesis. …”
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