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Neuropharmacological profile and chemical analysis of fresh rhizome essential oil of Curcuma longa (turmeric) cultivated in Southwest Nigeria
Published 2017-01-01“…This study determined the chemical composition of the essential oil of C. longa and evaluated its neuropharmacological activity in mice. Methods: Essential oil of C. longa (EOCL) fresh rhizome was obtained by hydrodistillation and its chemical composition determined by GCâMS. …”
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The mechanism of antidepressant action of a new 3-substituted thiethane-1,1-dioxide derivative in tests of neuropharmacological interaction
Published 2022-12-01“…Introduction: The present study is aimed at investigation of the mechanism of action of a new 3-substituted thietane-1,1-dioxide derivative (N-199/1) exhibiting antidepressant properties, in several tests of neuropharmacological interaction. Materials and methods: To study the mechanism of action of N-199/1, its effect on 5-hydroxytryptophan (5-HTP)-induced head-twitch response (50 mg/kg and 300 mg/kg), haloperidol-induced catalepsy (1 mg/kg), arecoline-induced tremor (6 mg/kg), picrotoxin-induced seizures (6 mg/kg) and hypothermia, induced by apomorphine (10 mg/kg) or L-3,4-dihydroxyphenylalanine (L-DOPA, 140 mg/kg), was assessed when administered singly to white outbred male mice at a dose of 2 mg/kg. …”
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Investigation of Potential Antioxidant, Thrombolytic and Neuropharmacological Activities of <i>Homalomena aromatica</i> Leaves Using Experimental and In Silico Approaches
Published 2021-02-01“…The purpose of this study was to explore in vitro antioxidant, thrombolytic activities, and in vivo neuropharmacological effects of methanolic extract of <i>Homalomena aromatica</i> (MEHA) leaves. …”
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Neuropharmacological Effects in Animal Models and HPLC-Phytochemical Profiling of <i>Byrsonima crassifolia</i> (L.) Kunth Bark Extracts
Published 2023-01-01“…The present work evaluated the neuropharmacological and analgesic effects of hydroalcoholic and dichloromethane extracts of <i>B. crassifolia</i>. …”
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Neuropharmacological Modulation of N-methyl-D-aspartate, Noradrenaline and Endocannabinoid Receptors in Fear Extinction Learning: Synaptic Transmission and Plasticity
Published 2023-03-01Subjects: “…neuropharmacology…”
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