Showing 13,541 - 13,560 results of 18,176 for search '"neuroprotective"', query time: 0.28s Refine Results
  1. 13541

    Repetitive anodal transcranial direct current stimulation improves neurological recovery by preserving the neuroplasticity in an asphyxial rat model of cardiac arrest by Chenxi Dai, Jianjie Wang, Jingru Li, Juan Wang, Lei Zhang, Changlin Yin, Yongqin Li

    Published 2021-03-01
    “…Conclusion: In this rat model of asphyxial CA, repetitive anodal tDCS commenced after resuscitation improved neurological recovery, and it may exert a neuroprotective effect by preserving the neuroplasticity.…”
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  2. 13542

    From Combinations to Single-Molecule Polypharmacology—Cromolyn-Ibuprofen Conjugates for Alzheimer’s Disease by Claudia Albertini, Marina Naldi, Sabrina Petralla, Silvia Strocchi, Daniela Grifoni, Barbara Monti, Manuela Bartolini, Maria Laura Bolognesi

    Published 2021-02-01
    “…We investigated their immunomodulatory profile in immortalized microglia cells, in vitro anti-aggregating activity towards Aβ<sub>42</sub>-amyloid self-aggregation, and their cellular neuroprotective effect against Aβ<sub>42</sub>-induced neurotoxicity. …”
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  3. 13543

    GSK2606414 attenuates PERK/p-eIF2α/ATF4/CHOP axis and augments mitochondrial function to mitigate high glucose induced neurotoxicity in N2A cells by Chayanika Gundu, Vijay Kumar Arruri, Bhoomika Sherkhane, Dharmendra Kumar Khatri, Shashi Bala Singh

    Published 2022-01-01
    “…Collectively, our findings revealed the neuroprotective potential of GSK2606414 against high glucose induced neurotoxicity in N2A cells.…”
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  4. 13544

    Bioactivities and molecular mechanisms of polysaccharides from Hericium erinaceus by Jianhui Liu, Weiwei Wang, Qiuhui Hu, Xuyang Wu, Hui Xu, Anxiang Su, Minhao Xie, Wenjian Yang

    Published 2022-06-01
    “…Both in vitro and in vivo studies have shown that HEP possesses antioxidant and anti-aging, gastrointestinal protecting, anti-tumor, hypolipidemic and hypoglycemic, immune-enhancing, neuroprotective, and hepatoprotective activities, verifying its functional benefits to human health. …”
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  5. 13545

    Transplantation of Human Umbilical Cord Mesenchymal Stem Cells-Derived Neural Stem Cells Pretreated with Neuregulin1β Ameliorate Cerebral Ischemic Reperfusion Injury in Rats by Qiu-Yue Zhai, Yu-Qian Ren, Qin-Shuai Ni, Zhen-Hua Song, Ke-Li Ge, Yun-Liang Guo

    Published 2022-03-01
    “…Additionally, NSCs-10 nM NRG1β intervention may function through regulating the p53/GPX4/SLC7A11 pathway, and reducing the level of ferroptosis in cells, further enhance the neuroprotective effect on injured cells.…”
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  6. 13546

    Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba) by Nadini Oliveira Martins, Isabella Modelli de Brito, Sandra Syomara O. Araújo, Giuseppina Negri, Elisaldo de Araújo Carlini, Fúlvio Rieli Mendes

    Published 2018-06-01
    “…Pre-clinical studies with T. catigua extracts have identified many pharmacological properties, such as anti-inflammatory, antidepressant, antinociceptive, pro-memory and neuroprotective against ischemia and oxidative stress. …”
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  7. 13547

    Estrogen and progesterone attenuate glutamate neurotoxicity via regulation of EAAT3 and GLT-1 in a rat model of ischemic stroke by Sara Nemati Pour, Zeinab Vahidinia, Majid Nejati, Homayon Naderian, Cordian Beyer, Abolfazl Azami Tameh

    Published 2020-10-01
    “…It has been shown that estrogen and progesterone act as neuroprotective agents after brain injury. This study aims to investigate the role of hormone therapy after middle cerebral artery occlusion (tMCAO) in the expression of GLT-1 and EAAT3 as glutamate transporters.…”
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  8. 13548

    Advances and perspectives in chemical and biological studies of Baphicacanthus cusia: a focus on antitumor constituents by Zhi-Hui Feng, Shuang Jing, Yu-Ping Shen, Yu-Qing Tong, Cheng-Jie Xiao, Jian-Ping Xue, Hong Zhang, Qi-Zhang Li, Lei Zhang

    Published 2024-01-01
    “…Modern pharmacological studies have revealed that B. cusia has numerous bioactive properties, such as antitumor, antiviral, anti-inflammatory, antioxidant, hepatoprotective, and neuroprotective properties. Moreover, B. cusia has been employed in clinical settings for its antitumor activity. …”
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  9. 13549

    Palmitoylethanolamide Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Rats by Masatsugu Ohara, Shunsuke Ohnishi, Hidetaka Hosono, Koji Yamamoto, Qingjie Fu, Osamu Maehara, Goki Suda, Naoya Sakamoto

    Published 2018-07-01
    “…PEA has therapeutic anti-inflammatory, analgesic, and neuroprotective effects. However, the effects and roles of PEA in liver fibrosis remain unknown. …”
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  10. 13550

    Association Between Serum Uric Acid Levels and Suicide Attempts in Adolescents and Young Adults with Major Depressive Disorder: A Retrospective Study by Kong Y, Liu C, Zhang C, Wang W, Li Y, Qiu H, Wang G, Li D, Chen X, Lv Z, Zhou D, Wan L, Ai M, Chen J, Ran L, Kuang L

    Published 2022-07-01
    “…Yiting Kong,1,&ast; Chuan Liu,2,&ast; Chenyu Zhang,1 Wo Wang,2 Yalan Li,2 Haitang Qiu,1 Gaomao Wang,2 Daqi Li,2 Xiaorong Chen,2 Zhen Lv,2 Dongdong Zhou,2 Liyang Wan,2 Ming Ai,1 Jianmei Chen,1 Liuyi Ran,2,&ast; Li Kuang1,2,&ast; 1Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Mental Health Center, University-Town Hospital of Chongqing Medical University, Chongqing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Liuyi Ran, Mental Health Center, University-Town Hospital of Chongqing Medical University, Shapingba District, Chongqing, 401331, People’s Republic of China, Tel/Fax +86-023-65714061, Email ranliuyi@163.com Li Kuang, Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, Yuzhong District, Chongqing, 400016, People’s Republic of China, Tel/Fax +86-023-89012696, Email kuangli0308@163.comPurpose: Uric acid (UA) is thought to exert neuroprotective roles. The purpose of this study was to examine the association of serum UA with suicide attempts (SA) in adolescents and young adults with major depressive disorder (MDD).Patients and Methods: We retrospectively recruited  533 participants with MDD aged 13 to 25 years, of which 168 had a history of SA in the past three months and 365 did not have a history of SA. …”
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  11. 13551

    HPLC-DAD finger printing, antioxidant, cholinesterase, and α-glucosidase inhibitory potentials of a novel plant Olax nana by Muhammad Ovais, Muhammad Ayaz, Ali Talha Khalil, Sayed Afzal Shah, Muhammad Saeed Jan, Abida Raza, Muhammad Shahid, Zabta Khan Shinwari

    Published 2018-01-01
    “…The antioxidant and cholinesterase inhibitory results were considerable and can provide scientific basis for further studies on the neuroprotective and anti-Alzheimer’s potentials of this plant. …”
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  12. 13552

    Suppression of porcine hemagglutinating encephalomyelitis virus replication by resveratrol by Yuzhu Liu, Deguang Song, Xueli Liu, Yuanqi Wang, Gaili Wang, Yungang Lan

    Published 2022-12-01
    “…Resveratrol has been shown to exert neuroprotective and antiviral effects. Here resveratrol was investigated for its ability to inhibit PHEV replication in nerve cells and central nervous system tissues. …”
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  13. 13553

    Serum BDNF and GDNF in Chinese male patients with deficit schizophrenia and their relationships with neurocognitive dysfunction by Xiaowei Tang, Chao Zhou, Ju Gao, Weiwei Duan, Miao Yu, Wenhuan Xiao, Xiaobin Zhang, Hui Dong, Xiang Wang, Xiangrong Zhang

    Published 2019-08-01
    “…Finally, higher serum GDNF levels are associated with better cognitive performance in DS patients, indicating a possible neuroprotective function in DS.…”
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  14. 13554

    Olfactory and cognitive decrements in 1991 Gulf War veterans with gulf war illness/chronic multisymptom illness by Linda L. Chao

    Published 2024-01-01
    “…Because impaired olfactory function has been associated with increased risk for MCI and dementia, it may be prudent to screen aging, deployed GW veterans with smell identification tests so that hypo- and anosmic veterans can be followed longitudinally and offered targeted neuroprotective therapies as they become available.…”
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  15. 13555

    A Rho-kinase inhibitor reverses learning and memory deficits in a Rat model of chronic cerebral ischemia by altering Bcl-2/Bax-NMDAR signaling in the cerebral cortex by Ming Ni, Jigang Zhang, Lin Huang, Gaolin Liu, Qin Li

    Published 2018-10-01
    “…In summary, our data provide evidence supporting the hypothesis that Rho-kinase inhibitors exert neuroprotective effects on cerebral ischemia. The Bcl-2/Bax-NMDAR signaling pathway in the cerebral cortex may be responsible for the protective effects of the Rho-kinase inhibitor, and this pathway may represent a pharmacological target for curative clinical strategies. …”
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  16. 13556

    Exogenous interleukin 33 enhances the brain’s lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice by Mingqi Liu, Jinhao Huang, Tao Liu, Jiangyuan Yuan, Chuanxiang Lv, Zhuang Sha, Chenrui Wu, Weiwei Jiang, Xuanhui Liu, Meng Nie, Yupeng Chen, Shiying Dong, Yu Qian, Chuang Gao, Yibing Fan, Di Wu, Rongcai Jiang

    Published 2023-04-01
    “…The lymphatic drainage system of the brain, composed of the glymphatic system and meningeal lymphatic vessels (MLVs), plays an essential role in the clearance of toxic waste after brain injury. The neuroprotective effect of interleukin 33 (IL-33) in TBI mice has been demonstrated; however, its impact on brain lymphatic drainage is unclear. …”
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  17. 13557

    RNA-seq based transcriptome analysis of ethanol extract of saffron protective effect against corticosterone-induced PC12 cell injury by Xi Chen, Ting Yang, Congen Zhang, Zhijie Ma

    Published 2022-01-01
    “…The study aimed to explore the neuroprotective effect of ethanol extract of saffron (EES) on corticosterone (CORT)- induced injury in PC12 cells and further explored its potential mechanism. …”
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  18. 13558
  19. 13559

    Platelet glycogen synthase kinase 3β regulates plasma β amyloid and phosphorylated tau levels in chronic kidney disease patients with cognitive dysfunction; therapeutic role of ery... by Vinothkumar Ganesan, Krishnakumar Sethuraman, Sureshkumar Sureshkumar, Venkataraman Prabhu

    Published 2023-09-01
    “…Recombinant human erythropoietin (rHuEPO) is a common medicine for treating anemia in patients with CKD, as well as a neuroprotective agent. Objectives: The goal of this research is to find out how platelet GSK3β regulates plasma Aβ, total Tau and tau phosphorylated at threonine 181 (p-tau181) levels in CKD patients with cognitive dysfunction and also the efficacy of rHuEPO treatment. …”
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  20. 13560

    <i>Ducrosia</i> spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review by Javad Mottaghipisheh, Anahita Boveiri Dehsheikh, Mohammad Mahmoodi Sourestani, Tivadar Kiss, Judit Hohmann, Dezső Csupor

    Published 2020-07-01
    “…Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. …”
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