Showing 1 - 20 results of 1,501 for search '"neurotransmission"', query time: 0.52s Refine Results
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    Amyloid Precursor Protein (APP) and GABAergic Neurotransmission by Bor Luen Tang

    Published 2019-06-01
    “…The discovery of these novel roles and activities of APP in GABAergic neurotransmission underlies the physiological importance of APP in postnatal brain function.…”
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    Article
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    Dynamic control of the dopamine transporter in neurotransmission and homeostasis by Mengfei Bu, Matthew J. Farrer, Habibeh Khoshbouei

    Published 2021-03-01
    “…Abstract The dopamine transporter (DAT) transports extracellular dopamine into the intracellular space contributing to the regulation of dopamine neurotransmission. A reduction of DAT density is implicated in Parkinson’s disease (PD) by neuroimaging; dopamine turnover is dopamine turnover is elevated in early symptomatic PD and in presymptomatic individuals with monogenic mutations causal for parkinsonism. …”
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    Article
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    Autism Spectrum Disorder: Focus on Glutamatergic Neurotransmission by Martina Montanari, Giuseppina Martella, Paola Bonsi, Maria Meringolo

    Published 2022-03-01
    “…In addition, preclinical studies on animal models have demonstrated glutamatergic neurotransmission deficits and altered expression of glutamate synaptic proteins. …”
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    Article
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    GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol by Gabriele Ruffolo, Alessandro Gaeta, Beatrice Cannata, Camilla Pinzaglia, Eleonora Aronica, Alessandra Morano, Pierangelo Cifelli, Eleonora Palma

    Published 2022-12-01
    “…Here, by using the microtransplantation of human brain membranes approach in <i>Xenopus</i> oocytes and electrophysiological recordings, we confirm the ability of CBD to modulate GABAergic neurotransmission in human cerebral tissues obtained from patients afflicted by different forms of pharmaco-resistant epilepsies, such as DS, TSC, focal cortical dysplasia (FCD) type IIb and temporal lobe epilepsy (TLE). …”
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    The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy by Tomasz Guzel, Dagmara Mirowska-Guzel

    Published 2022-03-01
    “…Serotonin acts via numerous types of receptors and clinically plays a role in several neural, mental, and other chronic disorders, such as migraine, carcinoid syndrome, and some dysfunctions of the alimentary system. 5-HT acts as a paracrine hormone and growth factor. 5-HT receptors in both the brain and gut are targets for drugs modifying serotonin neurotransmission. The aim of the present article is to review the 5-HT receptors in the gastrointestinal (GI) tract to determine the role of serotonin in GI physiology and pathology, including known GI diseases and the role of serotonin in GI pharmacotherapy.…”
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    Glycine receptor autoantibodies disrupt inhibitory neurotransmission by Crisp, SJ, Dixon, CL, Jacobson, L, Chabrol, E, Irani, SR, Leite, MI, Leschziner, G, Slaght, SJ, Vincent, A, Kullmann, DM

    Published 2019
    “…We conclude that human glycine receptor autoantibodies disrupt glycinergic neurotransmission, and also suggest that the pathogenic mechanisms include direct antagonistic actions on glycine receptors.…”
    Journal article
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    Memory Enhancement with Kynurenic Acid and Its Mechanisms in Neurotransmission by Diána Martos, Bernadett Tuka, Masaru Tanaka, László Vécsei, Gyula Telegdy

    Published 2022-04-01
    “…This study confirmed that a low dose of KYNA improved a memory component of cognitive domain, which was mediated by, at least in part, four systems of neurotransmission in an animal model of learning and memory.…”
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    Modeling Neurotransmission: Computational Tools to Investigate Neurological Disorders by Daniela Gandolfi, Giulia Maria Boiani, Albertino Bigiani, Jonathan Mapelli

    Published 2021-04-01
    “…The investigation of synaptic functions remains one of the most fascinating challenges in the field of neuroscience and a large number of experimental methods have been tuned to dissect the mechanisms taking part in the neurotransmission process. Furthermore, the understanding of the insights of neurological disorders originating from alterations in neurotransmission often requires the development of (i) animal models of pathologies, (ii) invasive tools and (iii) targeted pharmacological approaches. …”
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    Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission by Maria Nicol Colombo, Maura Francolini

    Published 2019-08-01
    “…Presynaptic terminals of neuromuscular junctions contain and release glutamate that contribute to the regulation of synaptic neurotransmission through its interaction with pre- and post-synaptic receptors activating downstream signaling pathways that tune synaptic efficacy and plasticity. …”
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    Brain 5-HT neurotransmission during paroxetine treatment. by Sargent, P, Williamson, D, Cowen, P

    Published 1998
    “…The effect of these adaptive changes on different aspects of brain 5-HT neurotransmission and their clinical consequences are not well understood. …”
    Journal article
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