The Spinal α7-Nicotinic Acetylcholine Receptor Contributes to the Maintenance of Cancer-Induced Bone Pain by Yang T, Zhou Y, Zhang W, Zhang L, Chen S, Chen C, Gao F, Yang H, Manyande A, Wang J, Tian Y, Tian X

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Neuroimmune nexus in the pathophysiology and therapy of inflammatory disorders: Role of α7 nicotinic acetylcholine receptors by Kasey R. Keever, Valentin P. Yakubenko, Donald B. Hoover

Subjects: “…α7 nicotinic acetylcholine receptor…”
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Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids by Marco Aurelio Sartim, Camila O. S. Souza, Cassiano Ricardo A. F. Diniz, Vanessa M. B. da Fonseca, Lucas O. Sousa, Ana Paula F. Peti, Tassia Rafaella Costa, Alan G. Lourenço, Marcos C. Borges, Carlos A. Sorgi, Lucia Helena Faccioli, Suely Vilela Sampaio

“…Hexamethonium, a nicotinic acetylcholine receptor antagonist, hampered late phase damages indicating that CTX-induced lung impairment could be associated with cholinergic transmission. …”
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Monkey adrenal chromaffin cells express α6β4* nicotinic acetylcholine receptors. by Alicia Hernández-Vivanco, Arik J Hone, Mick L Scadden, Beatriz Carmona-Hidalgo, J Michael McIntosh, Almudena Albillos

“…Nicotinic acetylcholine receptors (nAChRs) that contain α6 and β4 subunits have been demonstrated functionally in human adrenal chromaffin cells, rat dorsal root ganglion neurons, and on noradrenergic terminals in the hippocampus of adolescent mice. …”
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Single-cell quantitative expression of nicotinic acetylcholine receptor mRNA in rat hippocampal interneurons. by Doris C Jackson, Richard M Burgon, Spencer Thompson, Sterling N Sudweeks

“…Using single-cell quantitative PCR to analyze rat CA1 hippocampal interneurons, we quantified neuronal nicotinic acetylcholine receptor (nAChR) mRNA subunit expression and detailed possible nAChR subtype combinations for the α2, α3, α4, α5, α7, β2, β3, and β4 subunits. …”
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Expression and function of nicotinic acetylcholine receptors in specific neuronal populations: Focus on striatal and prefrontal circuits by Alice Abbondanza, Anna Urushadze, Amanda Rosanna Alves-Barboza, Helena Janickova

Subjects: “…Nicotinic acetylcholine receptors…”
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Expression and Possible Role of Nicotinic Acetylcholine Receptor ε Subunit (AChRe) in Mouse Sperm by Yusei Makino, Yuuki Hiradate, Kohei Umezu, Kenshiro Hara, Kentaro Tanemura

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Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors by Romain Durand-de Cuttoli, Sarah Mondoloni, Fabio Marti, Damien Lemoine, Claire Nguyen, Jérémie Naudé, Thibaut d'Izarny-Gargas, Stéphanie Pons, Uwe Maskos, Dirk Trauner, Richard H Kramer, Philippe Faure, Alexandre Mourot

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Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning. by Patricia G Izquierdo, Claude L Charvet, Cedric Neveu, A Christopher Green, John E H Tattersall, Lindy Holden-Dye, Vincent O'Connor

“…This reinforces the under investigated potential of using therapeutic approaches which target a modulation of nicotinic acetylcholine receptor function to treat the poisoning effects of this important class of neurotoxins.…”
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α7 Nicotinic Acetylcholine Receptor May Be a Pharmacological Target for Perioperative Neurocognitive Disorders by Penghui Wei, Wenyuan Lyu, Lin Xu, Lin Xu, Hao Feng, Haipeng Zhou, Jianjun Li

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Membrane-mediated interaction of non-conventional snake three-finger toxins with nicotinic acetylcholine receptors by Zakhar O. Shenkarev, Yuri M. Chesnokov, Maxim M. Zaigraev, Anton O. Chugunov, Dmitrii S. Kulbatskii, Milita V. Kocharovskaya, Alexander S. Paramonov, Maxim L. Bychkov, Mikhail A. Shulepko, Dmitry E. Nolde, Roman A. Kamyshinsky, Evgeniy O. Yablokov, Alexey S. Ivanov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova

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The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke by Katherine Hernandez, Nathan Jones, Sterling B. Ortega

“…Using a murine transient middle cerebral artery occlusion (tMCAO) model, we sought to evaluate the neurotherapeutic efficacy of a positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor (α7-nAChR), PNU-120596 (PNU), specifically examining whether PNU would modulate stroke-induced neurological dysfunction and neuropathology, with modulation of neuroinflammation as a possible mechanism.MethodsYoung male C57BL/6J mice received a subcutaneous injection of 20mg/kg of vehicle (DMSO) or PNU-120596 immediately after reperfusion, and infarct area and Bederson score were analyzed 24 hours post-stroke. …”
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Pursuing High-Resolution Structures of Nicotinic Acetylcholine Receptors: Lessons Learned from Five Decades by Manuel Delgado-Vélez, Orestes Quesada, Juan C. Villalobos-Santos, Rafael Maldonado-Hernández, Guillermo Asmar-Rovira, Raymond C. Stevens, José Antonio Lasalde-Dominicci

Subjects: “…nicotinic acetylcholine receptors…”
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Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium. by Souhei Sakata, Fumihito Ono

“…Early studies suggested that a classical non-depolarizing muscle relaxant pancuronium competitively binds to the ligand binding site to block nicotinic acetylcholine receptors (nAChR). Our group recently showed that nAChR which has two distinct subunit combinations are expressed in zebrafish muscles, αβδε and αβδ, for which potencies of pancuronium are different. …”
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Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins by William R. Kem, Kristin Andrud, Galen Bruno, Hong Xing, Ferenc Soti, Todd T. Talley, Palmer Taylor

“…In spite of its size, it acts as an antagonist at insect and mammalian nicotinic acetylcholine receptors (nAChRs). The functional importance of the disulfide bond was assessed by determining the effects of inserting a methylene group between the two sulfur atoms, creating dimethylaminodithiane (DMA-DT). …”
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Neuroinflammation Modulation via α7 Nicotinic Acetylcholine Receptor and Its Chaperone, RIC-3 by Tehila Mizrachi, Adi Vaknin-Dembinsky, Talma Brenner, Millet Treinin

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Effect of stimulated platelets in COVID-19 thrombosis: Role of alpha7 nicotinic acetylcholine receptor by Lina Jankauskaite, Lina Jankauskaite, Mantas Malinauskas, Ausra Snipaitiene

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Downregulation of alpha7 nicotinic acetylcholine receptor in two-kidney one-clip hypertensive rats by Chen Ji-Kuai, Zhao Ting, Ni Min, Li Dong-Jie, Tao Xia, Shen Fu-Ming

“…The role of the alpha7 nicotinic acetylcholine receptor (α7nAChR) in inflammation has recently been identified. …”
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αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish by Matthew J. Rybin, Henrik O’Brien, Iris Bea L. Ramiro, Layla Azam, J. Michael McIntosh, Baldomero M. Olivera, Helena Safavi-Hemami, Doju Yoshikami

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Alpha5 Nicotinic Acetylcholine Receptor Contributes to Nicotine-Induced Lung Cancer Development and Progression by Hai-Ji Sun, Yan-Fei Jia, Xiao-Li Ma

Subjects: “…alpha5 nicotinic acetylcholine receptor…”
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