Behavioral effects of a low molecular weight peptide fraction from Phaseolus vulgaris in rats by D. Graziani, J.V.V. Ribeiro, L.C. Turones, E.A. Costa, L.L. Reis-Silva, E.G. Araújo, L.G.F. de Paula, M.D. Ferreira-Junior, R.M. Gomes, H.M. Campos, P.C. Ghedini, K.A. Batista, K.F. Fernandes, C.H. Xavier

“…Brain areas of chronically treated groups were dissected to assess: i) lipid peroxidation (LPO); ii) carbonylated proteins (CP); iii) superoxide dismutase (SOD) and catalase (CAT) enzymatic activities. Neuronal nitric oxide synthases (nNOS) and argininosuccinate synthase (ASS) protein expression was evaluated by western blotting. …”
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MAP kinases differentially bind and phosphorylate NOS3 via two unique NOS3 sites by Xzaviar K. V. Solone, Amber L. Caldara, Brady Wells, Hao Qiao, Lydia R. Wade, John C. Salerno, Katy A. Helms, Katherine E. R. Smith, Jonathan L. McMurry, Carol A. Chrestensen

“…Nitric oxide synthase 3 (NOS3) is a major vasoprotective enzyme that catalyzes the conversion of l‐arginine to nitric oxide (NO) in response to a significant number of signaling pathways. …”
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S-Nitrosylation in endothelial cells contributes to tumor cell adhesion and extravasation during breast cancer metastasis by T. Koning, F. Cordova, G. Aguilar, J. Sarmiento, G. A. Mardones, M. Boric, M. Varas-Godoy, A. Lladser, W. N. Duran, P. Ehrenfeld, F. A. Sanchez

“…Abstract Background Nitric oxide is produced by different nitric oxide synthases isoforms. NO activates two signaling pathways, one dependent on soluble guanylate cyclase and protein kinase G, and other where NO post-translationally modifies proteins through S-nitrosylation, which is the modification induced by NO in free-thiol cysteines in proteins to form S-nitrosothiols. …”
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Nitric Oxide-Dependent Mechanisms Underlying MK-801- or Scopolamine-Induced Memory Dysfunction in Animals: Mechanistic Studies by Paulina Cieślik, Anna Siekierzycka, Adrianna Radulska, Agata Płoska, Grzegorz Burnat, Piotr Brański, Leszek Kalinowski, Joanna M. Wierońska

“…The expression of constitutive nitric oxide synthases (cNOS), dimethylaminohydrolase (DDAH1) and protein arginine N-methyltransferases (PMRTs) 1 and 5 was evaluated, and the impact of the studied tool compounds on cGMP production and NMDA receptors was measured. …”
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Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota by Xiaoyu Gao, Yifan Hu, Yifan Hu, Yafei Tao, Shuangfeng Liu, Haowen Chen, Jiayi Li, Yan Zhao, Jun Sheng, Yang Tian, Yuanhong Fan

“…The results showed that CCAE not only decreased the serum vasoactive intestinal polypeptide (VIP), induced nitric oxide synthases (iNOS), and acetylcholinesterase (AchE) in STC mice but also increased the expression of gastrointestinal motility factors in colonic interstitial cells of Cajal (ICCs) and smooth muscle cells (SMCs), thereby significantly shortening the defecation time and improving the gastrointestinal transit rate. …”
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Thapsigargin-resistant thiacalix[4]arene C-1087-sensitive component of the contractile activity in rat myometrium reflects the functioning of plasma membrane calcium pump by Olga Tsymbalyuk, Tetyana Veklich, Roman Rodik, Sergiy Karakhim, Sergiy Vyshnevskyi, Vitaly Kalchenko, Sergiy Kosterin

“…The effects of С-1087 under the action of thapsigargin regarding the relaxation phase in the spontaneous myometrium contractions were removed after the preliminary blocking of nitric oxide synthases L-NAME (100 µM). Under the action of L-NAME, thiacalix[4]arene С-1087 (10 µM) caused complete inhibition of the relaxation process in the contraction of myometrium preparations, induced by high-potassium solution (80 mM). …”
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Energy and Arginine Density in the Diets of Arbor Acre Hens from 40 to 50 Weeks of Age: Effects on Development and Lipid Metabolism of Embryos by Zhongyu Wang, Jiawei Feng, Chunxu Yang, Shaoyang Mou, Yingjie Xie, Xiaoxue Duan, Zhongyu Li, Zhongpeng Bi, Tianshu Liu, Feng Li, Liangmei Xu

“…With the increase in maternal dietary energy and arginine levels, embryonic serum nitric oxide synthases levels (E11, E15, E19) increased significantly (<i>p</i> < 0.01). …”
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Combined Treatment with KV Channel Inhibitor 4-Aminopyridine and either γ-Cystathionine Lyase Inhibitor β-Cyanoalanine or Epinephrine Restores Blood Pressure, and Improves Survival... by Abdelouahab Bellou, Nacira Sennoun, Elhadi H. Aburawi, Richard L. Jayaraj, Seth L. Alper, Ibrahim Abdallah Alfaki, Javed Yasin, Subramanian Sekar, Mohamed Shafiuallah, Suhail Al-Salam, Abderrahim Nemmar, Elsadig Kazzam, Paul Michel Mertes, Suleiman Al-Hammadi

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Reactions of S-nitrosothiols with biomimetic iron complexes and other transition metals by Victor, Eric, Ph. D. Massachusetts Institute of Technology

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