Characterization and detection of and phylogenetic relationships among Xanthomonas oryzae pv. oryzae isolates from selected rice varieties in Peninsular Malaysia by Keshavarzi, Kavous

“…Comparison indicated that the 30 strains have 98% to 99% nucleotide homology to the sequences of 16S- 23S rDNA of Xoo accessions AB026287 and AY251004 from Japan and China, respectively. …”
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First report of Colletotrichum siamense causing blossom blight on Thai basil (Ocimum basilicum L.) in Malaysia by Ismail, Siti Izera, Rahim, Nur Adlina, Zulperi, Dzarifah

“…Internal transcribed spacer (ITS) region, calmodulin (CAL), actin (ACT), and chitin synthase-1 (CHS-1) were amplified using ITS5/ITS4 (White et al. 1990), CL1C/CL2C (Weir et al. 2012), ACT-512F/783R, and CHS-79F/CHS-345R primer sets (Carbone and Kohn 1999), respectively. A BLAST nucleotide search of ITS, CHS-1, CAL, and ACT sequences showed 100% similarity to Colletotrichum siamense ex-type cultures strain C1315.2 (GenBank accession nos.: ITS, JX010171; CHS-1, JX009865) and isolate BPDI2 (CAL, FJ917505; ACT, FJ907423). …”
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Systematic studies of orchid genus Coelogyne in Peninsular Malaysia by Yoh, Kok Hon

“…DNA extraction, PCR amplification and sequencing was performed on the 59 taxa using the four nucleotide sequence datasets from two distinct genomes, such as chloroplastid genes (rbcL, matK and trnL-F) and nuclear ribosomal gene (nrITS). …”
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First report of leaf blight on Parthenium hysterophorus caused by Nigrospora sphaerica in Malaysia by Zafri, Azim Syahmi, Muhamad Awang, Rita, Wahab, Aswad, Mokhtar, Anis Syahirah, Mohd Hata, Erneeza

“…MN339998) had at least 99% nucleotide identity to that of N. sphaerica (GenBank accession number. …”
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Molecular modulation of medical nutrition therapy in obese patients with type 2 diabetes mellitus by Tay, Sook Hui

“…Genotyping of single nucleotide polymorphism (SNP) of Pro12Ala and Gly482Ser from the PPAR gamma (PPARG) and PPARGC1A as well as Leu162Val polymorphism in PPAR alpha (PPARA) were conducted from PBMC of the T2DM with obesity patients. …”
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Genetic polymorphism in high hbf anemic pregnant women and the effect of stem cell factor and erythropoietin-treated K562 cells on erk signaling of mapk pathway by Za'ror, Yousef Saeed Mohammad Abu

“…Dysregulation of hemoglobin (Hb) including fetal hemoglobin (HbF) due to single-nucleotide polymorphism (SNP) have been reported to cause anemia in pregnancy. …”
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Phosphodiesterase and psychiatric disorders: a two-sample Mendelian randomization study by Miaomiao Jiang, Weiheng Yan, Yuyanan Zhang, Zhe Lu, Tianlan Lu, Dai Zhang, Jun Li, Lifang Wang

“…Methods Specifically, cyclic nucleotide PDEs were collected from genome-wide association studies (GWASs), including PDEs obtained by hydrolyzing both cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) (PDE1A, PDE2A, and PDE3A), specific to cGMP (PDE5A, PDE6D, and PDE9A) and cAMP (PDE4D and PDE7A). …”
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Molecular characterization of extended spectrum cephalosporin resistant Escherichia coli isolated from livestock and in-contact humans in Southeast Nigeria by Solomon O. Olorunleke, Solomon O. Olorunleke, Solomon O. Olorunleke, Solomon O. Olorunleke, Miranda Kirchner, Nicholas Duggett, Nicholas Duggett, Manal AbuOun, Onyinye J. Okorie-Kanu, Kim Stevens, Roderick M. Card, Kennedy Foinkfu Chah, John A. Nwanta, Lucy A. Brunton, Muna F. Anjum

“…Large numbers of single nucleotide polymorphisms (SNPs) in the core genome of isolates, even within the same clade by phylogenetic analysis, indicated high genetic diversity. …”
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Mycobacterium tuberculosis epidemiology in Oman: whole-genome sequencing uncovers transmission pathways by Hamza A Babiker, Amina Al-Jardani, Saleh Al-Azri, Robert A. Petit, Eltaib Saad, Sarah Al-Mahrouqi, Reham A.H. Mohamed, Salama Al-Hamidhi, Abdullah A. Balkhair, Najma Al Kharusi, Laila Al Balushi, Samiya Al Zadjali, Lucía Pérez-Pardal, Albano Beja-Pereira, Ahmed Babiker

“…Relatedness was assessed by generating core-genome single nucleotide polymorphism (SNP) distances. The incidence of TB was five cases per 100,000 persons in 2018 and seven cases per 100,000 persons in 2020 (R2 = 0.34, P = 0.60). …”
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Combination of Linkage Mapping, GWAS, and GP to Dissect the Genetic Basis of Common Rust Resistance in Tropical Maize Germplasm by Maguta Kibe, Christine Nyaga, Sudha K. Nair, Yoseph Beyene, Biswanath Das, Suresh L. M, Jumbo M. Bright, Dan Makumbi, Johnson Kinyua, Michael S. Olsen, Boddupalli M. Prasanna, Manje Gowda

“…To dissect the genetic architecture of CR resistance in maize, association mapping, in conjunction with linkage mapping, joint linkage association mapping (JLAM), and genomic prediction (GP) was conducted on an association-mapping panel and five F₃ biparental populations using genotyping-by-sequencing (GBS) single-nucleotide polymorphisms (SNPs). Analysis of variance for the biparental populations and the association panel showed significant genotypic and genotype x environment (GXE) interaction variances except for GXE of Pop4. …”
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A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum by Caroline Simmons, Justin Gibbons, Chengqi Wang, Camilla Valente Pires, Min Zhang, Faiza Siddiqui, Jenna Oberstaller, Debora Casandra, Andreas Seyfang, Liwang Cui, Thomas D. Otto, John H. Adams

“…Parasite population genetic studies have identified numerous genes, single-nucleotide polymorphisms (SNPs), and transcriptional signatures associated with altered artemisinin activity with SNPs in the Kelch13 (K13) gene being the most well-characterized artemisinin resistance marker. …”
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Genome-Wide Association Study Identifies <i>CDKN1A</i> as a Novel Locus Associated with Muscle Fiber Composition by Ekaterina A. Semenova, Hirofumi Zempo, Eri Miyamoto-Mikami, Hiroshi Kumagai, Andrey K. Larin, Rinat I. Sultanov, Konstantin A. Babalyan, Andrey V. Zhelankin, Takuro Tobina, Keisuke Shiose, Ryo Kakigi, Takamasa Tsuzuki, Noriko Ichinoseki-Sekine, Hiroyuki Kobayashi, Hisashi Naito, Jatin Burniston, Edward V. Generozov, Noriyuki Fuku, Ildus I. Ahmetov

“…Approximately 45% of muscle fiber composition is heritable, however, single nucleotide polymorphisms (SNP) underlying inter-individual differences in muscle fiber types remain largely unknown. …”
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A biologically informed polygenic score of neuronal plasticity moderates the association between cognitive aptitudes and cortical thickness in adolescents by Xavier Navarri, Daniel E. Vosberg, Jean Shin, Louis Richer, Gabriel Leonard, G. Bruce Pike, Tobias Banaschewski, Arun L.W. Bokde, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Zdenka Pausova, Tomáš Paus

“…Using Gene Ontology, we first identified 199 genes implicated in neuronal plasticity, which mapped to 155,600 single nucleotide polymorphisms (SNPs). Second, we estimated their effect sizes from an educational attainment meta-GWAS to build a PGS-NP. …”
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Genomic Diversity of a Globally Used, Live Attenuated Mycoplasma Vaccine by Sara M. Klose, Olusola M. Olaogun, Jillian F. Disint, Pollob Shil, Miklós Gyuranecz, Zsuzsa Kreizinger, Dorottya Földi, Salvatore Catania, Marco Bottinelli, Arianna Dall'Ora, Anneke Feberwee, Marleen van der Most, Daniel M. Andrews, Gregory J. Underwood, Chris J. Morrow, Amir H. Noormohammadi, Marc S. Marenda

“…MS-H is a temperature-sensitive strain that is generated via the chemical mutagenesis of a virulent M. synoviae isolate, 86079/7NS. 32 single nucleotide polymorphisms have been found in the genome of MS-H compared to that of 86079/7NS, including 25 in predicted coding sequences (CDSs). …”
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Population Study of Ovarian Cancer Risk Prediction for Targeted Screening and Prevention by Faiza Gaba, Oleg Blyuss, Xinting Liu, Shivam Goyal, Nishant Lahoti, Dhivya Chandrasekaran, Margarida Kurzer, Jatinderpal Kalsi, Saskia Sanderson, Anne Lanceley, Munaza Ahmed, Lucy Side, Aleksandra Gentry-Maharaj, Yvonne Wallis, Andrew Wallace, Jo Waller, Craig Luccarini, Xin Yang, Joe Dennis, Alison Dunning, Andrew Lee, Antonis C. Antoniou, Rosa Legood, Usha Menon, Ian Jacobs, Ranjit Manchanda

“…Consenting individuals completed risk assessment and underwent genetic testing (<i>BRCA1/BRCA2/RAD51C/RAD51D/BRIP1</i>, OC susceptibility single-nucleotide polymorphisms). A validated OC risk prediction algorithm provided a personalised OC risk estimate using genetic/lifestyle/hormonal OC risk factors. …”
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Transcriptomic Analysis of Heat Stress Response in <i>Brassica rapa</i> L. ssp. <i>pekinensis</i> with Improved Thermotolerance through Exogenous Glycine Betaine by Jin Quan, Xinyuan Li, Zewei Li, Meifang Wu, Biao Zhu, Seung-Beom Hong, Jiang Shi, Zhujun Zhu, Liai Xu, Yunxiang Zang

“…The analysis of the KEGG enrichment pathways revealed that the most abundantly up-regulated pathways were protein processing in endoplasmic reticulum (14 genes), followed by plant hormone signal transduction (12 genes), ribosome (8 genes), MAPK signaling pathway (8 genes), homologous recombination (7 genes), nucleotide excision repair metabolism (5 genes), glutathione metabolism (4 genes), and ascorbate and aldarate metabolism (4 genes). …”
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Exploring the mechanism of curcumin in the treatment of colon cancer based on network pharmacology and molecular docking by Qingmin He, Qingmin He, Chuan Liu, Xiaohan Wang, Xiaohan Wang, Kang Rong, Kang Rong, Mingyang Zhu, Mingyang Zhu, Liying Duan, Liying Duan, Pengyuan Zheng, Pengyuan Zheng, Pengyuan Zheng, Yang Mi, Yang Mi, Yang Mi

“…The KEGG pathway enrichment analysis yielded 34 signaling pathways, mainly involved in Metabolic pathways, Nucleotide metabolism, Nitrogen metabolism, Drug metabolism - other enzymes, Pathways in cancer,PI3K-Akt signaling pathway, etc. …”
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Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunityResearch in context by James I. Robinson, Md Yuzaiful Md Yusof, Vinny Davies, Dawn Wild, Michael Morgan, John C. Taylor, Yasser El-Sherbiny, David L. Morris, Lu Liu, Andy C. Rawstron, Maya H. Buch, Darren Plant, Heather J. Cordell, John D. Isaacs, Ian N. Bruce, Paul Emery, Anne Barton, Timothy J. Vyse, Jennifer H. Barrett, Edward M. Vital, Ann W. Morgan

“…B-cells were evaluated by highly-sensitive flow cytometry. Single nucleotide polymorphism and copy number variation for genes encoding five FcγRs were measured using multiplex ligation-dependent probe amplification. …”
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Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice by Ya-Jing Zhu, Jing Huang, Ru Chen, Yu Zhang, Xin He, Wen-Xin Duan, Yuan-Lei Zou, Meng-Mei Sun, Hui-Li Sun, Si-Min Cheng, Hao-Chuan Wang, Hao Zhang, Wen-Ning Wu

“…Abstract Background Major depressive disorder (MDD) is a common but severe psychiatric illness characterized by depressive mood and diminished interest. Both nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing 1 (NLRP1) inflammasome and autophagy have been reported to implicate in the pathological processes of depression. …”
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Association between GLO1 variants and gestational diabetes mellitus susceptibility in a Chinese population: a preliminary study by Qiaoli Zeng, Qiaoli Zeng, Qiaoli Zeng, Taili Yang, Taili Yang, Wenfeng Wei, Dehua Zou, Dehua Zou, Yue Wei, Yue Wei, Fengqiong Han, Jieyun He, Jinzhi Huang, Jinzhi Huang, Runmin Guo, Runmin Guo, Runmin Guo, Runmin Guo

“…BackgroundGlyoxalase 1 (GLO1) plays a crucial role in defending against glycation. Single nucleotide polymorphism (SNP) variants in the GLO1 gene may affect gene expression and alter enzyme activity. …”
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