Role of cell-cell signaling, differentiation and fitness in multi-species biofilms by Lee, Kelvin Kai Wei

“…The morphotypic variants were also stable after daily passaging, while sequencing of their genomes showed that they possessed insertions/deletions and single nucleotide polymorphisms that might lead to changes in their phenotypes and morphotypes. …”
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Investigating the causal relationship of c-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium mendelian randomization study by Prins, B, Abbasi, A, Wong, A, Vaez, A, Nolte, I, Franceschini, N, Stuart, P, Guterriez Achury, J, Mistry, V, Bradfield, J, Valdes, A, Bras, J, Shatunov, A, Lu, C, Han, B, Raychaudhuri, S, Bevan, S, Mayes, M, Tsoi, L, Evangelou, E, Nair, R, Grant, S, Polychronakos, C, Radstake, T, van Heel, D, Dunstan, M, Wood, N, Al-Chalabi, A, Dehghan, A, Hakonarson, H, Markus, H, Elder, J, Knight, J, Arking, D, Spector, T, Koeleman, B, van Duijn, C, Martin, J, Morris, A, Weersma, R, Wijmenga, C, Munroe, P, Perry, J, Pouget, J, Jamshidi, Y, Snieder, H, Alizadeh, B

“…The first GRS consisted of four single nucleotide polymorphisms (SNPs) in the CRP gene (GRS_CRP), and the second consisted of 18 SNPs that were significantly associated with CRP levels in the largest genome-wide association study (GWAS) to date (GRS_GWAS). …”

Untangling the links between obesity and cancer using genomic and phenomic approaches by Harris, B

“…Through a novel approach, integrating inherited and somatic cancer genetic data, single nucleotide polymorphisms were identified which associate with different cancer types and differential gene expression in at least one tissue type (eSNPs). …”

Internal ribosome entry site for expression of infectious bursal disease viral segments A and B genes in Arabidopsis thaliana (L.) Heynh by Liew, Pit Sze

“…Prior to expression in the plant, complete nucleotide (nt) coding sequence of the UPM04/190 IBDV isolate was determined. …”
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Genome sequencing and pathogenicity of recent infectious bursal disease viruses in Malaysia by Bako, Aliyu Hayatuddeen

“…The isolates were detected using reverse transcription-polymerase chain reaction (RT-PCR) targeting the hypervariable region (HVR) of the VP2 gene. The nucleotide and amino acid (aa) sequences were compared with the previously characterised IBDV strains. …”
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Vitamin b12 and folic acid in the synthesis of methionine by micro-organisms by Guest, J

“…Cobalamin could be replaced by several of its nucleotide-substiuted analogues but not by derivatives lacking the nucleotide residue. …”

Genome-Wide Identification and Expression Pattern of ABC Transporters in Razor Clam (Sinonovacula constricta) by Fan YANG, Zhiping LI, Yinghui DONG, Jianfeng REN

“…ABC transporters can be classified as full transporters, which contain two nucleotide-binding domains (NBDs) and two transmembrane domains (TMDs), a half-transporter (composed of one NBD and one TMD), and a non-transporter (composed of either two NBDs or two TMDs incapable of transporting). …”
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First report of two consecutive respiratory syncytial virus outbreaks by the novel genotypes ON‐1 and NA‐2 in a neonatal intensive care unit by Daniella Gregoria Bomfim Prado da Silva, Flávia Jacqueline Almeida, Mariana Volpe Arnoni, Marco Aurélio Palazzi Sáfadi, Marcelo Jenne Mimica, Daniel Jarovsky, Gabriela Pereira de Almeida Rossetti, Mauricio Magalhães, Danielle Bruna Leal de Oliveira, Luciano Matsumiya Thomazelli, Thais Cristina Colmanetti, Edison Luiz Durigon, Eitan Naaman Berezin

“…Genotyping was performed using nucleotide sequencing. Results: From May to August 2013, two different outbreaks were detected in the neonatal intensive care unit. …”
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The severity of COVID-19 in hypertensive patients is associated with mirSNPs in the 3′ UTR of ACE2 that associate with miR-3658: In silico and in vitro studies by Muhammad Safdar, PhD, Mehmet Ozaslan, PhD, Rebaz M. Mustafa, MSC, Shukur W. Smail, MSC, Samiha S. Khan, MBBS, Muhammad Sajjad Khan, PhD, Muhammad Asad Akhtar, MSC, Hafiz Khawar Ali, MSC, Umair Younas, PhD, Muhammad Saeed, PhD, Faisal Siddique, PhD, Muhammad Naveed, PhD, SaifUr Rehman, PhD

“…Results: Interestingly, the binding site of miR-3658 corresponding to the 3′ UTR of ACE2 featured three SNPs (rs1457913029, C>T; rs960535757, A>C, G; rs1423809569, C>T), and its genomic sequence featured a single SNP (rs1024225815, C>T) with the same nucleotide variation (rs1457913029, C>T) which potentially increases the severity of COVID-19. …”
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Phylogeny and ecology of the Himalayan wolf by Werhahn, G

“…The phylogenetic distinction of the Himalayan wolf from the Holarctic grey wolf is supported by mitochondrial DNA (D-loop and cytochrome b), the ZF protein gene sequences on the Y and Z sex chromosomes, a microsatellite panel of 17 loci, and four Single Nucleotide Polymorphisms (SNPs) covering three hypoxia-pathway related functional nuclear genes.…”

Development of Real-Time Polymerase Chain Reaction Assays for the Detection and Differentiation of Infectious Bursal Disease Virus Subtypes by Kong, Lih Ling

“…Both approaches were able to detect and differentiate IBDV subtypes based on the use of subtype-specific primers or subtype-specific probes where the primers were designed based on single nucleotide polymorphism (SNP) concept. After optimization of the primer combinations and PCR parameters, very virulent-specific primer, IF & IVIR, and classical-specific primer, IF & RCLA were used in the SYBR Green I real-time RT-PCR assay. …”
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An Exploration of the Effects of Gene-Editing Technology on Human Identity by Ava Allwardt

“…Researchers can use CRISPR to cure a sickle cell disease patient by changing just one nucleotide in a human’s genome.[14] The editing of the patient’s genome changes their physical identity because genes are a physical component of humans, but mental changes can also result. …”
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Utilization of Molecular Systems for the Identification and Typing of Clinically Relevant Multiple Drug Resistant Staphylococcus Aureus by Neela, Vasantha Kumari

“…Sequencing of the Sa442 fragment from isolates obtained from the different geographical locations identified this fragment as an epidemiological marker as it showed a wide variation of 1-10 % in the nucleotide sequences among the S. aureus isolates studied. …”
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Impact of Marker Pruning Strategies Based on Different Measurements of Marker Distance on Genomic Prediction in Dairy Cattle by Duanyang Ren, Jinyan Teng, Shuqi Diao, Qing Lin, Jiaqi Li, Zhe Zhang

“…With the availability of high-density single-nucleotide polymorphism (SNP) data and the development of genotype imputation methods, high-density panel-based genomic prediction (GP) has become possible in livestock breeding. …”
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Studies on the metabolic changes accompanying bacteriophage infection by Haslam, E

“…The presence of the unusual base provides a means of identifying phase DNA in the infected cell, and of studying the phage-induced alterations of metabolism necessary for the biosynthesis of the unusual nucleotide. The virulent phages of <em>B</em>. <em>subtilis</em> have therefore been further investigated.…”

Growth performance morphomeristic and genetic characterization of crossbreeding between gift and UPM red tilapia by Francis, Nwachi Oster

“…Pure 2 has the highest nucleotide diversity (0.0302) with a total of 4 control regions while the other stains have one single region. …”
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Association of the TPO gene in Colombian families with type 1 diabetes Asociación del gen TPO en familias colombianas con la diabetes tipo 1 by Federico Uribe Londoño, Andrés Ruiz Linares, Gabriel Bedoya Berrío, Vital Balthazar González, Javier Gutiérrez Achurry, Nicolas Pineda Trujillo, Juan Manuel Alfaro

“…&lt;/span&gt;&lt;/p&gt;&lt;p class="MsoNormal" style="text-align: justify; line-height: 200%; margin: 0cm 0cm 0pt; mso-layout-grid-align: none;"&gt;&lt;span style="line-height: 200%; font-family: 'Times New Roman','serif'; font-size: 12pt; mso-ansi-language: EN-US;"&gt;For further characterization, the probands were tested for autoantibodies against insulin, TPO and thyrosine phosphatase 2 (IA-2). Two single nucleotide polymorphisms (SNPs) (rs4927611 and rs732609) were tested in TPO. …”
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Engineering functional nanomaterials for photonic applications by Chan, Kok Ken

“…K-ras regulates many downstream single molecules such as Raf kinase, Raf guanine, and nucleotide exchange factors that regulate cell growth, differentiation, and survival. …”
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Microbiological studies of some peptide antibiotics by Duncan, M, Duncan, Margaret J.

“…The percentage yield of protoplasts was measured by comparing their content of ethanol-extractable nucleotide with that obtained from a known weight of intact mycelium. …”